Chinese medicine compound percutaneous absorption patch for treating menorrhalgia and preparation method thereof
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A transdermal and compound technology is applied in the field of traditional Chinese medicine for the treatment of dysmenorrhea, and achieves the effects of long medicinal effect, high content of active ingredients and clear medicinal effect.
Inactive Publication Date: 2008-09-24
TIANJIN ZHONGBAO PHARMACY
View PDF0 Cites 6 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
It has no direct inhibitory effect on the cerebral cortex, but it can block the ascending
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
preparation example Construction
[0038] The preparation method of the traditional Chinese medicine compound transdermal absorption patch for treating dysmenorrhea of the present invention comprises the following steps:
[0039] (1) CO was used for the powder or coarse powder of Chinese herbal medicines Angelica and Turmeric respectively. 2 Supercritical extraction device, under the conditions of pressure 30MPa and temperature 50-55°C, extract for 3-4 hours to obtain angelica extract and turmeric extract respectively;
[0040] (2) The traditional ethanol extraction method is used for the material powder or coarse powder of the Chinese medicinal material Corydalis Corydalis to obtain Corydalis Corydalis extractum extract;
[0041] (3) Take angelica extract, turmeric extract, and β-cyclodextrin inclusion compound in proportion, and disperse them strongly through a nano-microemulsion disperser to control the microemulsion particles at the nanoscale to prepare a microemulsion dispersion;
[0042] (4) Add transd...
Embodiment 1
[0049] formula:
[0050] Angelica CO 2 Supercritical Extraction Oil 6g
[0051] Turmeric CO 2 Supercritical Extraction Oil 3g
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention discloses a Chinese traditional medicine compound trans-dermal absorption plaster for treating dysmenorrhea and a preparation method thereof. The plaster is prepared with the following materials by weight ratios: 0.5-3 shares of angelica extract, which is extracted from angelica by carbon dioxide supercritical extraction; 4-6 shares of fumitory extract, which is extracted from fumitory by traditional extraction method; 1-3 shares of turmeric extract, which is extracted from Chinese traditional medicinal materials by carbon dioxide supercritical extraction; 0.5-2 shares of trans-dermal accelerant; and 100-150 shares of pressure-sensitive adhesive. The materials are dispersed by nano-microemulsion dispersing machine intensively, and the particle diameter of the microemulsion is limited in nano-grade. The trans-dermal absorption preparation of the invention enters into the Subcutaneous capillary through skin cell gaps, and gets to the focus along with the blood circulation; the biological availability is improved by more than 10 times higher than the equivalent products, the curative effect is improved notably, the usage is convenient, and the adaptability of the sufferer is improved.
Description
technical field [0001] The invention relates to a traditional Chinese medicine for treating dysmenorrhea, in particular to a traditional Chinese medicine compound transdermal absorption patch for treating dysmenorrhea and a preparation method thereof. Background technique [0002] Transdermal drug delivery system or percutaneous absorption patch refers to a type of preparation that is applied through the skin, and the drug is absorbed through the skin into the blood circulation of the whole body and reaches an effective blood concentration to achieve disease treatment or prevention. The characteristic of the transdermal absorption patch is that the transdermal drug delivery system can avoid the first-pass effect of the liver and the inactivation of the drug in the gastrointestinal tract. Effective blood concentration or physiological effects, avoiding the peak and valley phenomenon of blood concentration caused by oral administration. Reduce toxic and side effects, reduce a...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more 
Login to view more