A pharmaceutical formulation for treating skin sensibility
A technology for pharmaceutical preparations and allergic diseases, applied in the field of pharmaceutical preparations for the treatment of skin allergies and its preparation, can solve the problems of large side effects and poor curative effect, and achieve safe use, strong anti-allergic and antipruritic effects, and good therapeutic effects Effect
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Embodiment 1
[0083] Raw materials: cetirizine hydrochloride 5g, vitamin B 6 5g, vitamin B 2 5g, niacinamide 10g, calcium pantothenate 20g, biotin 0.25g, glycyrrhizin 12.5g, starch 395g, magnesium stearate 4.5g, 75% ethanol 150g, made into 1000 capsules.
[0084] Preparation:
[0085] 1. Ingredients: cetirizine hydrochloride, vitamin B 6 , Vitamin B 2 , niacinamide, calcium pantothenate, biotin, glycyrrhizin and starch are pulverized successively with a pulverizer and passed through a 60-mesh sieve, and mixed in a cone mixer for 2 hours to obtain a medicinal powder;
[0086] 2. Granulation: Move the mixed medicinal powder into a tank mixer, add ethanol, and stir for 30 minutes to make a suitable soft material. It is required to hold tightly with hands to form agglomerates, and lightly press with fingers, and the agglomerates will disintegrate into Appropriate; use a granulator to make wet granules through a 20-mesh stainless steel screen, not into strips, and store the wet granules in...
Embodiment 2
[0093] Raw materials: cetirizine hydrochloride 3g, vitamin B 6 6g, vitamin B 2 7g, niacinamide 12g, calcium pantothenate 18g, biotin 0.2g, glycyrrhizin 10g, starch 400g, magnesium stearate 4.8g, 75% ethanol 145g, made into 1000 capsules.
[0094] Preparation:
[0095] 1. Ingredients: cetirizine hydrochloride, vitamin B 6 , Vitamin B 2 , niacinamide, calcium pantothenate, biotin, glycyrrhizin and starch are pulverized successively with a pulverizer and passed through a 60-mesh sieve, and mixed in a cone mixer for 2 hours to obtain a medicinal powder;
[0096] 2. Granulation: Move the mixed medicinal powder into a tank mixer, add ethanol, and stir for 30 minutes to make a suitable soft material. It is required to hold tightly with hands to form agglomerates, and lightly press with fingers, and the agglomerates will disintegrate into Appropriate; use a granulator to make wet granules through a 15-mesh stainless steel screen, not into strips, and store the wet granules in a ...
Embodiment 3
[0100] Raw materials: cetirizine hydrochloride 4g, vitamin B 6 3g, vitamin B 2 6g, niacinamide 11g, calcium pantothenate 22g, biotin 0.3g, glycyrrhizin 14g, starch 395g, magnesium stearate 4.5g, 75% ethanol 155g, made into 1000 tablets.
[0101] Preparation method: mix cetirizine hydrochloride, vitamin B 6 , Vitamin B 2 , nicotinamide, calcium pantothenate, biotin, glycyrrhizin and starch are crushed in turn and passed through a 60-mesh sieve, mixed evenly, and 75% ethanol is added to make the soft material, and the soft material is made into wet granules through a 25-mesh sieve with a granulator, at 75°C Dried until the water content does not exceed 4%, cooled to room temperature, crushed into fine powder with a 60-mesh sieve, added with magnesium stearate, mixed evenly, and pressed into tablets to obtain the product.
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