Injection for treating paratyphoid of dogs and preparation method thereof

A technology for injection and paratyphoid fever, applied in the field of compound sulfamethoxazole sodium injection and preparation thereof, can solve the problems of inability to kill bacteria quickly, decrease drug sensitivity, death of sick dogs, etc. The effect of preventing secondary infection and high cure rate

Inactive Publication Date: 2009-12-02
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the drugs used to treat canine paratyphoid fever, such as sulfamethoxine sodium, lincomycin hydrochloride and other drugs, due to the long-term exposure of bacteria in nature to antibiotics or antibacterial drugs, the sensitivi

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] (1) Weigh 2 kg of sulfamethoxine sodium into 10 L of water for injection, and stir until completely dissolved.

[0021] (2) Weigh 10kg of lincomycin hydrochloride and put it into 40L water for injection, stir until completely dissolved, then add 0.3kg of atropine sulfate, 0.06kg of dexamethasone sodium phosphate, 0.2kg of sodium bisulfite, 0.01kg of EDTA-2Na kg, stirred until completely dissolved.

[0022] (3) Combine the solution prepared in step 1 and step 2, then add water for injection to 100L, stir evenly, keep it for 15-20min, after the liquid medicine is clear, adjust the pH value to 10.0-11.0, which is the preparation of the present invention. Injection for the treatment of canine paratyphoid.

Embodiment 2

[0024] (1) Weigh 15kg of sulfamethoxine sodium into 30L of water for injection, and stir until completely dissolved.

[0025] (2) Weigh 1kg of lincomycin hydrochloride and put it into 20L water for injection, stir until completely dissolved, then add atropine sulfate 0.05kg, dexamethasone sodium phosphate 0.06kg, sodium bisulfite 0.2kg, EDTA-2Na 0.01 kg, stirred until completely dissolved.

[0026] (3) Combine the solution prepared in step 1 and step 2, then add water for injection to 100L, stir evenly, keep it for 15-20min, after the liquid medicine is clear, adjust the pH value to 10.0-11.0, which is the preparation of the present invention. Injection for the treatment of canine paratyphoid.

Embodiment 3

[0028] (1) Weigh 5 kg of sulfamethoxine sodium into 10 L of water for injection, and stir until completely dissolved.

[0029] (2) Weigh 7kg of lincomycin hydrochloride and put it into 40L water for injection, stir until completely dissolved, then add 0.2kg of atropine sulfate, 0.06kg of dexamethasone sodium phosphate, 0.2kg of sodium bisulfite, 0.01kg of EDTA-2Na kg, stirred until completely dissolved.

[0030] (3) Combine the solution prepared in step 1 and step 2, then add water for injection to 100L, stir evenly, keep it for 15-20min, after the liquid medicine is clear, adjust the pH value to 10.0-11.0, which is the preparation of the present invention. Injection for the treatment of canine paratyphoid.

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PUM

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Abstract

The invention discloses an injection for treating the paratyphoid of dogs and a preparation method thereof, which aim to provide an injection which has quick effect and can reduce the drug resistant probability of pathogenic bacteria, treat both symptoms and root causes and quicken the recovery, and a preparation method which has simple process and is easy to realize. Per 100L of the injection comprises 2-15kg of sulfamonomethoxine sodium, 1-10kg of lincomycin hydrochloride, 0.05-0.3kg of atropine sulfate, 0.06kg of dexamethasone sodium phosphate, 0.2kg of sodium bisulfite, 0.01kg of EDTA-2Na and the balance of water. The injection adopts antibacterial drugs, antibiotics, glucocorticoids for diminishing inflammation and detoxifying and atropine sulfate for controlling the diarrhea of the dogs and reducing dehydration, and a compound preparation prepared by reasonably proportioning the dosages of the components has the function of double anti-bacteria, can reduce the drug resistant probability of salmonella typhimuria, control the infection of other gram negative bacteria and positive bacteria and accelerate the recovery and has high cure rate.

Description

technical field [0001] The invention relates to a compound sulfamethoxine sodium injection for treating canine paratyphoid and a preparation method thereof. Background technique [0002] Canine paratyphoid is a disease caused by Salmonella typhimurium. This bacterium is widely distributed in nature. Under normal circumstances, healthy dogs are carriers. It often hides in the digestive tract and lymphatic tissue. When the resistance drops, the bacteria can proliferate and cause endogenous infection to cause illness. At the same time, incompletely cooked and spoiled food can cause infection. The main manifestations are diarrhea, lethargy, anorexia, vomiting, abdominal pain, rapid system failure, pale mucous membranes, and finally dehydration, shock and death. [0003] At present, the drugs used to treat canine paratyphoid fever, such as sulfamethoxine sodium, lincomycin hydrochloride and other drugs, due to the long-term exposure of bacteria in nature to antibiotics or antiba...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/505A61K31/7056A61K31/46A61K31/573A61P31/04A61P1/12
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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