Preparation method of masking agent for bitter animal medicines with irritant odor

Abstract

The invention discloses a preparation method of a masking agent for bitter animal medicines with irritant odor, which relates to raw materials and a preparation technique of a medicine assistant. Themethod mainly comprises the following steps: mixing main materials comprising polyvinyl alcohol, hydroxypropyl methylcellulose and the like, and assistants comprising ethyl cellulose and the like in certain proportions to prepare a water solution or ethanol solution with a certain concentration; evenly spraying the water solution or ethanol solution on the surface of the animal medicine granules;and drying for use. The masking agent can effectively mask the bitterness and the irritant odor of animal medicines and improve the conditions of the animals to accept the medicines. The masking agenthas the advantages of stable properties and long storage period and enhances the therapeutic effect of the medicines by controlling the dissolving positions of the medicines.

Description

1. Technical field: [0001] The invention relates to a pharmaceutical auxiliary material, in particular to a masking agent for bitter taste and pungent smell of veterinary medicine. 2. Technical background: [0002] Veterinary drug preparations often have a strong bitter taste for some reason during the application process, which affects the feed intake of livestock and poultry. The pigs that are more sensitive to smell have a greater impact on the feed intake. At the same time, the drug is unstable and irritating. It is easy to cause gastric ulcer or vomiting after eating, and it is easy to be inactivated in the stomach, which will affect the effect. Veterinary drugs such as polymyxin, florfenicol, tiamulin, tylosin, entafloxacin, and enrofloxacin have extremely strong bitter taste, which will affect the palatability of pigs, and the granulation of drugs is affected by temperature For example, ivermectin and tilmicosin are affected by light, oxygen, feed enzymes, minerals, ...

AI Technical Summary

Problems solved by technology

[0002] Veterinary drug preparations often have a strong bitter taste for some reason during the application process, which affects the feed intake of livestock and poultry, and the pigs that are more sensitive to smell have a greater impact on the feed intake. At the same time, the drug is unstable and irritating. It is easy to cause gastric ulcer or vomiting after eating, and it is easy to be inactivated in the stomach, which will affect the effect

Veterinary drugs such as colistin, florfenicol, tiamulin, tylosin, entafloxacin, and enrofloxacin have extremely strong bitter taste, which will affect the palatability of pigs, and the granulation of drugs is affected by temperature For example, ivermectin and tilmicosin are affected by light, oxygen, feed enzymes, minerals, etc. when adding medicine to feed or drinking water, so that the efficacy of the medicine is reduced