Preparation method of swertia pseudochinensis extractive in swertia pseudochinensis-silybum marianum liver benefiting product

Abstract

The invention discloses a preparation method of a swertia pseudochinensis extractive in a swertia pseudochinensis-silybum marianum liver benefiting product. The method comprises the following steps of: carrying out gradient refluxes to extract swertia pseudochinensis (the prescription quantity is 95 percent) for three times respectively by using 95 percent ethanol, 75 percent ethanol and 50 percent ethanol, filtering, combining filter liquors and concentrating an obtained filter liquor to a thick paste with a specific gravity of 1.20-1.30g / ml (80 DEG C); adding remainder fine swertia pseudochinensis powder (the prescription quantity is 5 percent) and mixing; spreading an obtained mixture into a roasting disk according to a proportion of 3-5Kg / disk; drying the mixture under the condition of setting the material temperature of a microwave vacuum drying and sterilizing machine to be 70-90 DEG C and the operation time to be 80-120min and controlling the vacuum degree to be -0.08 to -0.09MPa, pulverizing the dry paste and then sieving by a sieve of 80 meshes; and mixing to obtain dry swertia pseudochinensis paste powder. A drug product prepared by the drying method has stable quality and high active ingredient content.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a new method for preparing a Chinese medicine extract of Dangfei Liganning, a medicine for clearing away dampness and heat, benefiting the liver and reducing jaundice. Background technique [0002] Among the medicines for clearing dampness and heat, benefiting the liver and reducing jaundice, Dangfei Liganning is a standard traditional Chinese medicine preparation issued by the Ministry of the People's Republic of China. It is a pure natural medicine prepared from Dang medicine and milk thistle, which can protect liver cells Normal structure and function, reduce the damage of various poisons to liver cells, inhibit the formation of inflammatory mediator tumor necrosis factor, reduce alanine aminotransferase, promote bile excretion, have the effects of clearing away dampness and heat, benefiting the liver and reducing jaundice. It is used for jaun...

AI Technical Summary

Problems solved by technology

It was found that the temperature difference between the upper part and the lower part of the oven was above 10°C, which caused the material to be heated unevenly; and the bottom of the baking pan was directly in contact with the heating pipe, so the actual temperature of the material at the bottom of the baking pan was much higher than the temperature gauge of the oven. In the drying process, the control temperature of the oven is generally around 90°C, and the drying time is as long as more than 20 hours. Such a high temperature and uneven heating can easily carbonize the extract, and the dry paste has a burnt smell, which even causes Active ingredients are degraded or destroyed, reducing the quality of medicines; materials are prone to foaming and overflowing, and the extract sticks to the baking tray after drying, which is difficult to clean and heavy loss; water and electricity consumption is large, and the effective utilization rate of heat energy is low (less than 40%) ;Drying and paste collection operations require multiple people to work together, which is labor-intensive and consumes a lot of manpower; in addition, materials tend to form hard lumps during the drying process, which are difficult to crush, causing safety hazards to equipment and personnel