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Chinese medicine combination with health protection function

A technology of composition and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine composition with health-care effects, can solve the problems of inability to fully exert the compatibility of medicines, difficulty in drying thick ointment, and affecting product efficacy, and achieve long-term storage with stable quality, remarkable curative effect, The effect of convenience

Active Publication Date: 2010-06-09
LUNAN HOPE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, in the above preparation method, after utilizing ethanol to extract honeysuckle, due to the nature of its active ingredient chlorogenic acid itself, it is very tightly combined with ethanol, so it is difficult to dry the thick paste, which affects the production efficiency; and Scutellaria baicalensis contains baicalin and Containing wogonin, baicalein, wogonin and other baicalin flavonoids, baicalin flavonoids can inhibit the passive skin allergic reaction of guinea pigs and the allergic contraction reaction caused by the isolated small intestine and trachea to antigens, and can inhibit the release of tissue by mast cells. Amines can also inhibit the activity of cyclooxygenase and lipoxygenase, block the synthesis of prostaglandins and leukotrienes, thereby exerting anti-inflammatory and anti-allergic effects; baicalein and other components can exert the efficacy of total flavonoids of Scutellaria baicalensis It plays a role that cannot be ignored. For example, baicalein is widely used in the clinical treatment of infectious hepatitis, nephritis, pyelonephritis and other diseases. However, since baicalein and the like are almost insoluble in water, after water extraction of Scutellaria baicalensis, the original preparation can only be used as impurities. However, the utilization rate is reduced, the curative effect of the product is affected, and the concentration process after water extraction requires a large amount of energy; in addition, in the existing silver yellow preparation, the ratio of honeysuckle and scutellaria baicalensis cannot fully exert the compatibility of drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] The preparation method of Yinhuang buccal tablet of the present invention is as follows:

[0044] 1) Preparation of honeysuckle extract: decoct 10kg of dried honeysuckle water for 3 times, the weight ratio of honeysuckle to water is 1:12, 1:8, 1:4 respectively, and the decoction time is controlled to be 2, 1 and 0.5 hours respectively , the medicinal liquids are combined, filtered to remove drug residues, concentrated to a thick paste, and dried to obtain 2.87kg of honeysuckle extract;

[0045]2) Preparation of Scutellaria baicalensis extract: decoct 10 kg of Scutellaria baicalensis water twice, add 8 times the weight of Scutellaria baicalensis water for the first time, decoct for 2.5 hours, add 3 times the water for the second time, decoct for 1 hour, and combine the decoction liquid , filter to remove the drug residue, add hydrochloric acid to the filtrate to adjust the pH to 2-4, let it stand, filter the precipitate, wash with 40%-70% ethanol and concentrate to a thi...

Embodiment 2

[0053] Take 9g of the honeysuckle extract (calculated as chlorogenic acid), and 72g of the extract of Scutellaria baicalensis (calculated as baicalin), granulate, pack, and obtain.

Embodiment 3

[0055] The honeysuckle extract is calculated as chlorogenic acid 72g, the Scutellaria baicalensis extract is calculated as baicalin 9g, pulverized, compressed into tablets, and packaged.

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PUM

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Abstract

The invention relates to a Chinese medicine combination with a health protection function, comprising the following steps of firstly, decocting honeysuckles with water for 1-3 times to prepare a honeysuckle extractive; secondly, decocting scutellaria 1-3 times with water, combining decocted fluids and filtering, regulating pH of filtrate to 2-4, standing, leaching precipitations, washing with 40-70 percent ethanol and concentrating to prepare a scutellaria extractive; thirdly, respectively detecting contents of effective compositions in the honeysuckle extractive and the scutellaria extractive by using a liquid chromatography; and fourthly, preparing a yinhuang combination in a proportion, drying the yinhuang combination according to the needs of preparation forms, adding proper amount of auxiliary materials, and preparing into various preparation forms which can be clinically accepted through a conventional preparation method. The method solves the problem of difficult drying of a honeysuckle extractive thick paste, enhances the production efficiency and the utilization ratio of scutellaria so as to enable the concentration process to be easy to carry out, saves the energy and has remarkable curative effect by applying a yinhuang preparation including a yinhuang buccal tablet prepared by the method.

Description

technical field [0001] The invention relates to a pharmaceutical composition with health care function. In particular, a pharmaceutical composition for treating upper respiratory tract infection and a preparation method thereof. Background technique [0002] In my country, upper respiratory tract infections such as pharyngitis and tracheitis, pneumonia and respiratory virus infection are common and frequently-occurring diseases. Not only itself often protracted, but also can cause a variety of complications, endangering human health. With the development of industrial society, the air is polluted to varying degrees, which increases the incidence of upper respiratory tract infections and pneumonia-like diseases such as rhinitis and pharyngitis. Modern medicine believes that although the main pathogenic bacteria of this disease are streptococci, mixed infections of bacteria and viruses are not uncommon, and the resulting acute lymphadenitis, rheumatic fever, nephritis and ot...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61K9/20A61P11/00A61P11/04A61P11/14G01N30/02
Inventor 赵志全
Owner LUNAN HOPE PHARM CO LTD
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