Self-degradation bioactive metal anchoring nail and preparation method thereof

A bioactive, self-degradable technology, applied in the field of self-degradable bioactive metal anchors and their preparation, to achieve the effect of bone repair

Inactive Publication Date: 2010-06-30
CHANGSHU MICROTUBE TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Regarding the use of degradable magnesium alloy anchors for repair and fixation, there have been no reports at home and abroad. Me

Method used

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  • Self-degradation bioactive metal anchoring nail and preparation method thereof
  • Self-degradation bioactive metal anchoring nail and preparation method thereof
  • Self-degradation bioactive metal anchoring nail and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Melting 94wt% Mg-6wt% Zn alloy, lathe, grinding machine processing molding, nail head 1 longitudinal section is triangular, nail head 1 cross section is circular, nail body 2 is cylindrical with threads, nail tail 3 has a single hole and transverse The cross-section is circular, which is called a locking strip wire type. Finally, a fluorine-containing apatite coating is prepared on the surface of the anchor by electrodeposition to obtain a self-degrading bioactive fast-fixing metal anchor;

[0024] The locking strip line type prepared in this embodiment has a nail body 2 with a diameter of 6mm and a total length of 50mm, as shown in the example diagram figure 1 As shown, it is applied to the repair of rotator cuff tear. After the pre-drilled hole, the nail is driven into the bone, and the damaged tendon tissue is fixed with the thread in the hole. After implantation, no anchor prolapse, loosening, liquefaction, and rejection were found. Postoperative X-rays showed that ...

Embodiment 2

[0026] Melting 99.3wt% Mg-0.7wt% Ca alloy, lathe, grinding machine processing molding, nail head 1 longitudinal section is trapezoidal, nail head 1 cross section is circular, nail body 2 is semi-winged without thread, nail tail 3 An anchor with a circular cross-section and a fixing slot 4 is called a winged non-threaded fixing type, a self-degrading bioactive fast-fixing metal anchor;

[0027] The winged non-threaded fixed type prepared in this embodiment has no coating, the diameter of the nail body 2 is 1.8mm, and the total length is 5.4mm. The example is shown in the figure figure 2 As shown, it is applied to the repair of the flexion deformity of the distal interphalangeal joint caused by the extensor tendon rupture or avulsion in the I area of ​​the finger. The extensor tendon was sutured with mattress (double-needle cross) suture to reconstruct the insertion point of the extensor tendon. After the implantation, no complications such as anchor prolapse, loosening, lique...

Embodiment 3

[0029] Melting 99wt% Mg-1wt% Mn alloy, lathe, grinding machine processing molding, the longitudinal section of nail head 1 is trapezoidal, the cross section of nail head 1 is circular, the nail body 2 is semi-winged without thread, and the cross section of nail tail 3 It is a circular anchor with a fixing slot 4, called a winged non-threaded fixing type, a self-degrading bioactive fast-fixing metal anchor;

[0030] The winged non-threaded fixed type prepared in this embodiment has no coating, the diameter of the nail body 2 is 1.8mm, and the total length is 5.4mm. The example is shown in the figure figure 2 As shown, it is applied to the repair of flexion deformity of the distal interphalangeal joint caused by extensor tendon rupture or avulsion in zone I of the finger. The sutures of the 3 card slots 4 reconstruct the insertion point of the extensor tendon with a mattress-style (double-needle cross) suture. After the implantation, no complications such as anchor prolapse, l...

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Abstract

The invention relates to a self-degradation bioactive metal anchoring nail which belongs to the technical field of biomedicine. The self-degradation bioactive metal anchoring nail is made of magnesium or magnesium alloy, and the outer surface of the self-degradation bioactive metal anchoring nail can be optionally provided with a bone-like apatite coating. The magnesium alloy comprises the following components in percentage by mass: one or a plurality of 0.01-10% of Zn, 0.01-5% of Ca, 0.001-5% of Fe and 0.01-5% of Mn, and the balance of Mg. The invention basically ensures the biosafety. The magnesium or magnesium alloy matrix can be simultaneously provided with the bone-like apatite coating, thereby promoting the bone repair, enhancing the fixing strength, and overcoming the defects in the permanent implant metal anchoring nail and the degradable polymer anchoring nail. The self-degradation bioactive metal anchoring nail can better achieve the goals of healing and repairing of tendons and bone, achieve favorable tracing performance, and meet the requirements for comprehensive mechanical properties and biosafety of anchoring nail materials.

Description

technical field [0001] The invention relates to a device in the technical field of biomedicine and a preparation method thereof, in particular to a self-degrading bioactive metal anchor and a preparation method thereof. Background technique [0002] Rapid fixation anchors are widely used clinically for tendon displacement and fixation, ligament repair and reconstruction, tendon insertion reconstruction, acromioclavicular joint dislocation repair, Achilles tendon rupture, posterior cruciate ligament (PCL) tibial attachment avulsion Fractures, repair and reconstruction of the medial collateral ligament of the knee joint and soft tissue, etc., the anchors currently in clinical use are mostly metal anchors and biodegradable polymer absorbable anchors. The former includes metal titanium and stainless steel anchors, but because metal implants can cause damage and inflammation to the tissues around the anchor, and even lead to the migration of the anchor, it not only affects the fi...

Claims

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Application Information

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IPC IPC(8): A61L31/10A61L31/08A61L31/02A61L31/14
Inventor 李佳楠宋阳张绍翔赵常利张小农
Owner CHANGSHU MICROTUBE TECH
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