Multi-directional valve peripherally inserted central catheter with anticoagulant and antibacterial functions and preparation method thereof

Abstract

The invention discloses a multi-directional valve peripherally inserted central catheter with anticoagulant and antibacterial functions and a preparation method thereof, belonging to the field of medical devices. A tip of the catheter on the external structure of the catheter is closed, and a plurality of long slits are radially cut at the upper part of the tip of the catheter for forming valve channels; at least one antibacterial drug is permeated and distributed in the organizational structure of silicon rubber which is used as a material for manufacturing the catheter on the microscopic structure, an anticoagulant drug is grafted on the surface of the silicon rubber, the antibacterial drug is one or the combination of two of rifampicin and nitrofuran, the anticoagulant drug is heparin sodium, the number of long slits is 2-4, and the positions of the long slits are staggered in the transverse direction and the radial direction. The catheter can conveniently prevent infection and theoccurrence of phlebitis during the long-term indwelling process of the catheter, prevent thrombosis and blockage of the catheter during the using process and have the function of preventing blood backflow, thereby being the multifunctional PICC catheter with the latest design.

Description

Technical field: [0001] The invention relates to the field of medical instruments. Specifically relates to a peripheral central venous catheter (PICC) with antibacterial and anticoagulant functions and a multi-directional valve structure and a preparation method thereof. Background technique: [0002] At present, medical catheters are commonly made of silicone rubber. Although silicone rubber itself has a wide range of medical applications due to its excellent biocompatibility and beneficial properties such as not being bonded to body tissues, its function is relatively single; Patent 99113477.X has developed a medical catheter with an antibacterial coating on the basis of a silicone rubber catheter. Soak in coagulation solution and then dry, so that the treated medical silicone catheter has antibacterial and anticoagulant effects at the same time. However, its disadvantage is that too many auxiliary materials are used in the process of processing, such as polyurethane res...

AI Technical Summary

Problems solved by technology

It is of great significance to popularize high-tech intravenous infusion therapy, improve the success rate of rescuing patients, and improve the quality of life. However, the existing PICC tube has a single function, and there are problems such as thrombosis, catheter blockage, phlebitis, and catheter infection during use.

[0004] The use of peripheral central catheters (PICCs) directly contacts the blood environment of the human body. Therefore, the expansion of its anticoagulant and antibacterial functions requires a simpler coating to reduce unsafe factors for the human body. There is no literature yet A PICC tube with diverse functions and simple composition is disclosed

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