Degarelix acetate lyophilized powder injection and preparation method thereof
A technology of degarelix acetate and freeze-dried powder for injection is applied in the field of degarelix acetate freeze-dried powder for injection and its preparation, which can solve problems such as instability, achieve convenient clinical use, low production cost, and repeatability. good effect
Active Publication Date: 2011-10-05
蚌埠丰原涂山制药有限公司
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The invention provides a degarelix acetate lyophilized powder injection, which consists of degarelix acetate, mannitol and sodium acetate in the mass ratio of 1:(1.2-2):(0.02-0.1). The lyophilized powder injection is obtained by performing freeze drying on the degarelix acetate, the mannitol and the sodium acetate serving as main medicaments. In the preparation process, the stability and safety of a preparation are ensured strictly. The prepared degarelix acetate lyophilized powder injection has the advantages of low content of relevant substances, uniform and stable mass, complete moisture drying, stability in transportation, storage and using processes, convenience for clinical application, high stability and high biological activity, and the like. The preparation method adopted by the invention is simple and effective, has high repeatability and low production cost, and is easy for industrial production.
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