Capsule for treating ulcerative colitis

A technology for ulcerative colitis and capsules, which is applied in the field of traditional Chinese medicine preparations of Coptis chinensis and Muxiang, which can solve the problems of non-targeted release, low content of active ingredients, and large dosage
CN102228530AActive Publication Date: 2011-11-02SOUTHERN MEDICAL UNIVERSITY

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SOUTHERN MEDICAL UNIVERSITY
Publication Date
2011-11-02

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Abstract

The invention relates to a traditional Chinese medicine composition, and particularly relates to a capsule for treating ulcerative colitis. The content of the capsule is composed of the following ingredients in parts by weight: 24-56 parts of Radix Aucklandiae instant micropills and 49-105 parts of Rhizoma Coptidis colon-targeted micropills, wherein the Radix Aucklandiae instant micropills are composed of the following ingredients in parts by weight: 1 part of a Radix Aucklandiae volatile oil, 8-15 parts of beta-CD (cyclodextrin) and 16-40 parts of a shaping agent; and the Rhizoma Coptidis colon-targeted micropills are composed of the following ingredients in parts by weight: 24 parts of a Rhizoma Coptidis extract, 24-72 parts of a pill core excipient, 0.36-1.2 parts of acrylic resin L100-55, 1.08-3.6 parts of acrylic resin S100, 0.043-0.144 parts of diethyl phthalate and 0.28-0.96 parts of talcum powder. The capsule provided by the invention can separately release two different functional ingredients in the stomach and colon, and has the advantage of high drug availability.
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Description

technical field

[0001] The invention relates to the field of traditional Chinese medicines, in particular to traditional Chinese medicine compositions, in particular to traditional Chinese medicine preparations of Coptidis rhizome and woody incense. Background technique

[0002] Ulcerative colitis (Ulcerative Colitis, UC) is a multifactorial intestinal disease, with non-specific inflammatory lesions in the submucosa of the rectum and colon as the main symptom, mainly involving the rectum and sigmoid colon, and may also invade other parts or all colon and terminal ileum. The clinical manifestations are mainly abdominal pain, diarrhea, pus and blood in the stool or tenesmus and indigestion. Western medicine for the treatment of ulcerative colitis drugs are mainly aminosalicylic acid, adrenal cortex hormones, antibacterial drugs, immunosuppressive drugs and so on. These drugs can control the ulcer inflammation in patients, but the adverse reactions are many and serious, and t...

Claims

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