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Shijunzi extract and its extraction method

An extraction method and extraction technology, applied in the field of Gentleman Extract and its extraction, can solve the problems of ineffective extraction and achieve the effect of life extension

Inactive Publication Date: 2011-12-07
HAINAN STAND BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In clinical practice, it is often taken after decocting or stir-frying, and it is impossible to effectively extract and utilize the polysaccharide components in Shijunzi. Therefore, an extract of Shijunzi and a method for extracting polysaccharides from Shijunzi are provided, and the extract of Shijunzi It is used to prepare medicines and / or health products for treating tumors, which has practical significance

Method used

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  • Shijunzi extract and its extraction method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 The Herba Cinnamon Extract provided by the present invention

[0027] After cleaning the sun-dried Shijunzi fruit with clear water, remove the shell, take 2.0kg and grind it with a pulverizer, pass through a 20-mesh sieve to obtain Shijunzi powder, weigh 1.0kg Shijunzi powder and pack it into a round-bottomed flask, Add 3.0L of 95% ethanol, place it in a water bath at 80°C, install a cooling device, turn on the cooling switch, heat and reflux for extraction for 2 hours, collect the residue, add 3.0L of 95% ethanol, and extract under reflux to obtain the coarse powder of Junzi , repeat ethanol reflux 1 time, collect the precipitate and dry it to obtain the fine powder of the gentium.

[0028] Take 0.5kg of dried Shijunzi fine powder, add 6.00L of water, heat up to 50°C, soak and extract for 3 hours, cool to room temperature, adjust the pH value to 3.5 with 1mol / L citric acid, add 80,000 yuan per kg of Shijunzi powder IU of cellulase and 80,000 IU of pectinase ...

Embodiment 2

[0035] Example 2 The extract of Caesarium chinensis provided by the present invention

[0036] After cleaning the sun-dried Shijunzi fruit with clear water, remove the shell, take 2.0kg and grind it with a pulverizer, pass through a 40-mesh sieve to obtain Shijunzi powder, weigh 1.0kg Shijunzi powder and pack it into a round-bottomed flask, Add 2.0L of 95% ethanol, put it in a water bath at 60°C, install a cooling device, turn on the cooling switch, heat and reflux for extraction for 3 hours, collect the residue, add 2.0L of 95% ethanol, and extract under reflux to obtain the coarse powder of Junzi , repeated ethanol reflux 3 times, collected the precipitate and dried it to obtain the fine powder of the gentium.

[0037] Take 0.5kg of dried Shijunzi fine powder, add 4.00L of water, heat up to 60°C, soak and extract for 2 hours, cool to room temperature, adjust the pH value to 3.8 with 1mol / L hydrochloric acid, add 400,000 IU to each kg of Shijunzi powder Cellulase and 300,000...

Embodiment 3

[0044] Example 3 The extract of Caesarium chinensis provided by the present invention

[0045] After cleaning the dried Shijunzi fruit with clear water, remove the shell, take 2.0kg and grind it with a pulverizer, pass through an 80-mesh sieve to obtain Shijunzi powder, weigh 1.0kg Shijunzi powder and pack it into a round-bottomed flask, Add 5.0L of 95% ethanol, place it in a water bath at 70°C, install a cooling device, turn on the cooling switch, heat and reflux for extraction for 4 hours, collect the residue, add 5.0L of 95% ethanol, and extract under reflux to obtain the coarse powder of Junzi , repeat ethanol reflux 2 times, collect the precipitate and dry it to obtain the fine powder of Gentleman.

[0046] Take 0.5kg of dried Shijunzi fine powder, add 7.5L of water, heat up to 55°C, soak and extract for 3 hours, cool to room temperature, adjust the pH value to 4.0 with 1mol / L phosphoric acid, add 1.6 million IU per kg of Shijunzi powder Cellulase and 800,000 IU pectinas...

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Abstract

The invention relates to the technical field of biomedicine, in particular to a Rangoon creeper fruit extract and an extraction method thereof. According to the extraction method, polysaccharide is extracted from Rangoon creeper fruit by a biological enzymolysis technology, and the Rangoon creeper fruit extract with a higher polysaccharide purity is obtained by ethanol reflux extraction, water extraction, suction filtration, centrifugation, DEAE (diethylaminoethyl) column separation and purification, vacuum concentration and spray drying. The purity of the Rangoon creeper fruit polysaccharideis 72.7-78.2%, and the molecular weight of the polysaccharide is 21800-38900D. Shown by drug effect tests, the Rangoon creeper fruit extract provided by the invention has an inhibiting effect on S180sarcoma, has an effect on prolonging the life of a mouse with transplanted liver cancer H22, and can be used for preparing a medicament and / or health product for inhibiting tumor; and simultaneously,the Rangoon creeper fruit extract improves the effect on treating roundworm abdominal pain, infantile malnutrition, stagnation of milk and food, abdominal distention and diarrhea, and can be used forpreparing a medicament and / or health product for treating roundworm abdominal pain, infantile malnutrition, stagnation of milk and food, abdominal distention and diarrhea.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to an extract of the junzi and an extracting method thereof. Background technique [0002] Quisqualic indica L is a plant of the genus Quisqualis in the family Combretaceae, a deciduous climbing shrub that grows in sunny bushes such as plains, hillsides, and roadsides, and is mainly distributed in Southeast Asia, Fujian, and Taiwan in my country , Sichuan, Guangdong, Guangxi and other places. "Compendium of Materia Medica" records that the fruit, root, and leaves of this plant can be used as medicine, which has the functions of killing insects, eliminating stagnation, and invigorating the spleen. Wait. [0003] Modern studies have shown that making a gentleman mainly contains amino acids, tannins, polysaccharides and their glycosides, alkaloids, volatile oils, anthraquinones, steroids, coumarins and terpenoids. Among them, the junzi seed kernel contains about 0.5% quiscinic acid, whic...

Claims

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Application Information

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IPC IPC(8): C08B37/00C12S3/02A61K31/715A61P35/00A61P33/10A61P1/14A61P1/12A23L1/30
CPCY02A50/30
Inventor 韩金光王唐洪伍曾利
Owner HAINAN STAND BIO TECH
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