Method for preparing natural bone repairing material

A technology for repairing materials and natural bone, applied in medical science, prosthesis, etc., can solve the problems of allograft bone graft rejection, few sources of autologous bone graft, poor osteogenesis ability, etc., and achieve good histocompatibility, good mechanical The effect of improving the scientific characteristics and promoting the speed of repair
CN102274546BInactive Publication Date: 2013-07-10JIAMUSI UNIVERSITY
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
JIAMUSI UNIVERSITY
Publication Date
2013-07-10
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention discloses a method for preparing a natural bone repairing material, and relates to a method for preparing a bone repairing material, which is used for solving the problems of small quantity of autogenous bone transplant sources, rejection reaction existing in allogeneic bone transplant as well as low artificial bone induction osteogenic potential and small osteogenesis amount of an artificial bone repairing material existing in the conventional bone defects reconstruction. The method comprises the following steps of: clearing soft tissues and bone marrows on a cancellous bone, cutting into blocks, fixing, flushing, soaking, washing and sterilizing to obtain an antigen-removed cancellous bone; putting the antigen-removed cancellous bone into a thermal treatment furnace for calcining; extracting a fortune's drynaria rhizome extract; extracting an epimedium extract; extracting a Chinese teasel root extract; and putting the calcined cancellous bone into the fortune's drynaria rhizome extract, the epimedium extract or the Chinese teasel root extract for soaking, and drying to obtain the natural bone repairing material. Due to the adoption of the method, the size of the bone repairing material can be controlled, and the prepared bone repairing material has a natural porous structure and a smooth inner wall, is hydroxylapatite with a pure phase and completely-developed crystal gains, and is applied to bone defects reconstruction.
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Description

technical field

[0001] The invention relates to a preparation method of a bone repair material. Background technique

[0002] The pace of life is accelerating, and the frequent occurrence of diseases, traffic accidents, sports trauma, etc. has caused a sharp increase in people's accidental injuries. The development of biomedical materials for the regeneration and repair of human tissues and organs has significant social benefits.

[0003] Currently, bone defect repair methods mainly include autologous bone grafting, allogeneic bone grafting, and synthetic bone. Autologous bone graft has the characteristics of non-antigen, good osteoinductivity and osteoconductivity, but its source is limited. Bone allografts carry risks of transmission of other diseases, and there are legal and ethical issues that need to be addressed. Synthetic bone has better osteoconductivity and certain mechanical strength. It mainly acts as a scaffold to guide bone regeneration after being implanted ...

Claims

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