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Constant-temperature preparation method for submicron powder Wupi powder and special bidirectional airflow screening machine thereof

A technology of Wupi powder and ultrafine powder, which is applied in powder transportation, pharmaceutical formulations, medical preparations containing active ingredients, etc., and can solve the constraints of large-scale production of veterinary traditional Chinese medicine ultrafine powder, low bioavailability, and reduced crushing efficiency, etc. problems, to achieve the effect of being suitable for large-scale industrial production, increasing cell wall breaking rate, improving smell and taste

Active Publication Date: 2013-08-28
HENAN KANGXING PHARMA
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  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, Wupi powder used in livestock and poultry is mostly coarsely crushed powder, which has the disadvantages of large dose, coarse dosage form, poor appearance, etc., the active ingredients cannot be fully released, and the bioavailability is low, which seriously affects the quality of traditional Chinese medicine and clinical treatment effect. Moreover, it cannot be evenly mixed with pellet feed, and cannot be directly added to drinking water for use.
[0004] Traditional Chinese medicine ultrafine pulverization technology is an update and development of traditional pulverization technology. It not only retains the advantages of traditional Chinese medicine preparation technology, but also injects new vitality into the modern production of Chinese medicine. It has broad application prospects, but there are still some problems in actual production. Problems and problems: (1) Low production efficiency and high energy consumption are the main factors restricting the large-scale production of veterinary traditional Chinese medicine ultrafine powder
In the traditional closed-circuit crushing process of the rod mill, when most of the materials have reached the fineness requirement, there is always a small part of coarse powder mixed in it, and the crushing time needs to be greatly extended to further crush this part of the coarse powder to the required particle size , so that the crushing efficiency is reduced, and the energy consumption is greatly increased; (2) There is a difference in particle size uniformity of the material after classification in winnowing classification and classifying wheel classification, which greatly affects the production quality of Chinese veterinary drug compound superfine powder, especially in the application of animal When using drinking water, it is difficult to meet the usage requirements due to the existence of a small amount of unbroken cells
(3) In the traditional unidirectional airflow screening, when Chinese medicine is ultrafinely pulverized, as the particle size decreases, the surface area and surface energy of the material particles increase, the adsorption increases, the fluidity becomes poor, and it is easy to aggregate into large particles It is difficult to sieve and classify powders with a fineness of more than 200 mesh

Method used

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  • Constant-temperature preparation method for submicron powder Wupi powder and special bidirectional airflow screening machine thereof
  • Constant-temperature preparation method for submicron powder Wupi powder and special bidirectional airflow screening machine thereof
  • Constant-temperature preparation method for submicron powder Wupi powder and special bidirectional airflow screening machine thereof

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Embodiment Construction

[0059] like figure 1 , 2 Shown, the normal temperature preparation method of superfine powder Wupisan of the present invention comprises the following steps:

[0060] The first step is to select decoction pieces of mulberry white peel, dried tangerine peel, Dabupi peel, ginger peel, and Poria peel, and dry them naturally or dry to a moisture content of ≤10%;

[0061] The second step is to pulverize the above-mentioned raw materials at a temperature of 20°C to 25°C, respectively, to obtain a coarse powder of traditional Chinese medicine with a particle size of 60 to 80 meshes;

[0062] The 3rd step, the above-mentioned crude drug crude powder is mixed according to the weight ratio of mulberry white peel: dried tangerine peel: big belly peel: ginger peel: Poria peel=2:2:2:1:2;

[0063] The fourth step is to first turn on the powder conveying fan 15, the induced draft fan 5, the blower 11, and the drive motor 8. The blowing pressure of the powder conveying fan 15 is 24kpa, an...

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Abstract

The invention discloses a constant-temperature preparation method for submicron powder Wupi powder, comprising the following steps of: drying and smashing white mulberry root bark, pericarpium citri reticulatae, pericarpium arecae, ginger peel and poria peel cortex poriae crude drugs slice processed for decoction to obtain coarse powder; putting the coarse powder into a rod mill to be smashed at the following ratio: 2 parts of white mulberry root bark, 2 parts of pericarpium citri reticulatae, 2 parts of pericarpium arecae, 1 part of ginger peel and 2 parts of poria peel cortex poriae; sending into a special bidirectional airflow screening machine by wind to be screened by using a screen of 50 meshes; conveying a powder material of which the particle diameter is less than or equal to 25 micrometers into a cyclone material collector by airflow generated by an induced draft fan to be collected to obtain the finished product of the submicron powder Wupi powder; collecting the powder material which is not screened by using the screen of 500 meshes; and conveying into the rod mill via a pipeline to be cyclically smashed again. The constant-temperature preparation method for the submicron powder Wupi powder has the advantage that the whole preparation process is carried out at constant temperature, no low temperature or special additional conditions are required, the particle diameter of the finished product medicine is less than or equal to 25 micrometers, and the cell-wall breaking ratio and the bioavailability are greatly improved. According to the special bidirectional airflow screening machine used in the room-temperature preparation method, the preparation technology of the submicron powder Wupi powder is simplified.

Description

technical field [0001] The invention relates to the field of veterinary drug preparations, in particular to a method for preparing superfine powder Wupi powder at normal temperature; the invention also relates to a special two-way airflow sieving machine used in the method. Background technique [0002] Chinese herbal medicine has incomparable advantages over other chemically synthesized drugs in the prevention and treatment of diseases: high safety, less toxic and side effects, more active ingredients, less harmful residues, more targets of action, can play a combined effect, and is not easy to produce drug resistance It can regulate the body's immunity and enhance the body's disease resistance while antibacterial and antiviral. Under the background that countries around the world are increasingly emphasizing food safety and calling for green and ecological conditions, it is of great practical significance to promote the application of traditional Chinese veterinary drugs f...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K9/14B02C23/20A61P31/04
Inventor 刘永录曹凌杰于瑞王巧红马长宇
Owner HENAN KANGXING PHARMA