Medical scaffold with inner coating film, and preparation method for medical scaffold

Abstract

The invention relates to medical equipment, particularly a medical scaffold with an inner coating film, and a preparation method for the medical scaffold, and belongs to the field of medical equipment. In the medical scaffold with the inner coating film, a non-woven inner coating film of which fibers are distributed on the axial direction of the medical scaffold is prepared on the inner surface of an inner film by an electrospinning method by taking a coating film scaffold as a basis, wherein the coating film scaffold consists of a netlike scaffold which is formed by weaving medical alloy wires, an electrospinning non-woven inner film and an electrospinning non-woven outer film; and the thickness of the inner coating film is 2 to 6 mu m. During preparation of the medical scaffold with the inner coating film, the inner coating film, the inner film and the outer film are prepared sequentially, and the inner coating film in the medical scaffold improves the biocompatibility with tract tissues of a human body, facilitates adhesion, migration and reproduction of endothelial cells at two ends of the medical scaffold, promotes quick endothelialization of the medical scaffold, and prevents the medical scaffold from becoming narrow again. The preparation method for the medical scaffold is simple, convenient to operate, and low in cost, and suitable for preparation of medical scaffolds with different diameters and lengths.

Description

Technical field [0001] The invention relates to a medical device, more specifically to a medical stent covered with a film and a preparation method thereof, belonging to the scope of medical devices. Background technique [0002] The mesh stent woven with medical alloy wires can be applied to the esophagus, trachea, blood vessel, biliary tract, urethra and other parts of the intermediary therapy. It plays an important role in the reconstruction of the human body’s access, but the effective time is short and the restenosis rate is high. In order to reduce the stimulation of the inner wall of human tissues by the medical alloy wire mesh medical stent, reduce tissue regeneration, and reduce the re-embolization rate, people use manual sewing methods to cover a layer of film on the outer surface of the stent. This film can It is a drug-loaded membrane, which effectively prolongs the effective use time of the stent. However, due to the lack of adhesion between the stent and the membran...

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Problems solved by technology

[0004] In view of the above-mentioned problems, the purpose of the present invention is to solve the defects of the existing film-covered medical stent, and to add a layer of inner film that can promote rapid endothelialization on the inner surface of the electrospun non-woven film-covered medical stent, Provided is a medical stent with an inner membrane capable of promoting rapid endothelialization and a preparation method thereof

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