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Method for preparing pyruvic aldehyde dimethyl acetal

A technology of acetaldehyde dimethyl acetal and propylene glycol is applied in the field of compound preparation, which can solve the problems of excessive waste liquid, environmental pollution, and low product purity, and achieve the effects of reducing pollution, improving product quality, and improving yield.

Inactive Publication Date: 2012-07-04
WENZHOU OPAL CHEM IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] The waste liquid that is formed in the above-mentioned preparation method is more, has caused certain pollution to the environment, because non-resin catalyst can not be reused and synthetic cost is high, and reactant utilization rate is low, and the purity of product is not high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Methylglyoxal monohydrate embodiment: select a reactor with an inner diameter of 10mm and a length of 350mm, in which the constant temperature section is 55mm. Catalyst can choose Zn 2+ 、Ce 4+ , Pb 4+ 、Pr 3+ , La 3+ 、K + , ZrO 2 , α-Al 2 o 3 、Cu + , SiO 2 、H 3 PO 4 , (NH 4 )H 2 PO 4 , AgNO 3 It is obtained by modifying electrolytic silver, the dose is 3mL, and it is placed in a constant temperature section; the upper and lower parts are filled with quartz sand, and the reaction product is condensed in one stage to obtain aceglyoxal monohydrate, and the tail gas is then absorbed in multiple stages. The experimental device is entirely made of stainless steel. 1,2-propanediol is injected by a double plunger pump, water vapor is provided by a boiler and measured by a flow meter, and air and nitrogen are compressed air that is supplied by a steel cylinder after being measured by a flow meter. The optimum conditions for synthesis are: reaction temperature 350...

Embodiment 2

[0031] Add 100 grams of methylglyoxal monohydrate in a 1000ml three-necked flask equipped with a mechanical stirring device, a reflux condenser, and a thermometer. 3 COCHO.H 2 O meter 90%, 320.4 grams of industrial grade methanol, 40 grams of modified resin catalyst, vigorously stirred, heated and refluxed for 16 hours; cooled to room temperature, filtered, and filtered out the modified resin catalyst; the filtrate was injected into 1000ml equipped with a mechanical stirring device and a thermometer Distill in a three-necked flask with a distillation head with a controllable reflux ratio to distill off low boiling substances such as methylal and methyl acetate until the top temperature reaches 64°C; then recover methanol under the condition of variable reflux ratio to maintain the top Warm at 64~66°C until the temperature in the flask reaches 90°C; add water vapor to the lower part of the flask to continue distillation, and collect the crude acetoaldehyde dimethyl acetal solut...

Embodiment 3

[0033] Add 100 grams of methylglyoxal monohydrate (in CH 3 COCHO.H 2 (90% in O)), the front cut when refining in embodiment one, the raffinate after steam distillation, the front cut and raffinate when refining, the methyl alcohol that reclaims and fresh technical grade methanol total 320.4 grams, modified resin catalyst ( Recycling) 40 grams, stirred vigorously, heated to reflux for 16 hours; cooled to room temperature, filtered, and filtered out the modified resin catalyst; the filtrate was injected into a three-necked flask equipped with a mechanical stirring device, a thermometer and a distillation head with a controllable reflux ratio. Carry out distillation, distill out methylal, methyl acetate and other low boilers, until the top temperature reaches 64°C; then recover methanol under the condition of variable reflux ratio, maintain the top temperature at 64~66°C, until the temperature in the flask reaches 90 ℃; in the lower part of the flask, water vapor was introduced ...

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Abstract

The invention aims to solve the technical problem of providing a method for preparing pyruvic aldehyde dimethyl acetal, which has the advantages of reducing environment pollution and improving the utilization rate of reactants and the purity of a product. The method comprises the following steps of: synthesizing pyruvic aldehyde monohydrate by taking 1,2-propylene glycol as a raw material; reacting with methanol in the presence of a modified catalyst; separating the catalyst from the formed reaction solution; recovering the methanol; performing steam distillation to obtain a pyruvic aldehyde dimethyl acetal rough product; performing extraction and separation in water; and distilling to obtain the pyruvic aldehyde dimethyl acetal.

Description

technical field [0001] The invention relates to a preparation method of a compound, in particular to a preparation method of aceguvaldehyde dimethyl acetal. Background technique [0002] Related to the preparation method of aceguvaldehyde dimethyl acetal in the prior art mainly contains following documents: [0003] Document 1: BRAUDE AND EVANS, J.CHEM.SOC.3328(1955): Using 30% aceguvaldehyde and methanol, using sulfuric acid as catalyst, and benzene as entrainer for acetalization reaction, but pointed out that the product yield is low , and contains unreacted aldehyde. [0004] Document 2: DE2947383, Hoechst AG, 1979.11.24: 40% methylglyoxal was dehydrated with petroleum ether as an entrainer, and then acetalized with methanol using an ion exchange resin as a catalyst. [0005] Document 3: JP591999651A, Sumitomo Chemical Industry Co., Ltd., 1984.11.12: It is obtained by using 40% methylglyoxal aqueous solution and methanol in suspension, acetalization with ion exchanger, ...

Claims

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Application Information

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IPC IPC(8): C07C49/175C07C45/61
CPCY02P20/582Y02P20/584
Inventor 叶逊项一非项晓燕杜永安王鸿文
Owner WENZHOU OPAL CHEM IND