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Traditional Chinese medicine for preventing and curing recurrent aphthae and preparing method thereof

A technology of traditional Chinese medicine and Nansha ginseng, which is applied in the field of medical engineering, can solve the problems of inability to cure recurrent aphthous ulcers, strong irritation of the digestive tract, easy to cause diarrhea, etc., and achieves the effects of high prevention and treatment, no drug resistance and low price.

Inactive Publication Date: 2012-07-18
CHANGSHU HUAGANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above-mentioned existing Chinese patent medicines for the treatment of recurrent aphtha can temporarily relieve symptoms, they also cause discomfort in the mouth and cannot radically cure recurrent aphtha.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0059] The present invention also provides a preparation method of a traditional Chinese medicine for preventing and treating recurrent aphthous ulcers. When the dosage form of the traditional Chinese medicine is a capsule, it includes:

[0060] In the first step, the components are mixed in proportion, and ethanol with an alcohol concentration of 80% to 90% is heated and refluxed for 2 to 4 times, and the obtained extracts are combined, filtered, and concentrated under reduced pressure to remove 80% by mass. ~90% ethanol to obtain a concentrated solution, the quality of the added ethanol is 2 to 4 times the mass of the mixture;

[0061] In the second step, the above-mentioned concentrated solution is eluted through a macroporous adsorption resin column with deionized water or distilled water 3 to 5 times the volume of the resin column, and then 2 to 4 times the volume of the resin column with an alcohol concentration of 90% to 95%. Ethanol elution, collect the ethanol eluate,...

Embodiment 1

[0075] Embodiment 1 The toxicity test of Chinese medicine of the present invention

[0076] experimental drug

[0077] 23g Nansha ginseng, 15g Evodia rutaecarpa, 9g cinnamon, 14g notopterygium, 32g aloe vera, 38g Qingdai, 15g gallnut, 22g dogwood, 18g cistanche, 25g diffusa hedyotis, 25g flavescens, 12g polygala, 22g black plum, 68g coptis, plantain 20g of fruit, 16g of senna leaves, 15g of kudzu root, 25g of medlar, 35g of rehmannia root, 32g of Moutan cortex, 28g of licorice and 25g of Atractylodes macrocephala, mixed with 1600g of ethanol with an alcohol concentration of 90% and heated and refluxed for 3 times, and the obtained extract Merge, filter, concentrate under reduced pressure, remove 80% ethanol by mass percentage to obtain a concentrated solution, pass the concentrated solution through a 6LAB-8 macroporous adsorption resin column, and first elute with deionized water 4 times the volume of the resin column, and then use The alcohol concentration of 4 times of resi...

Embodiment 2

[0080] The preparation of embodiment 2 capsules

[0081] 23g Nansha ginseng, 15g Evodia rutaecarpa, 9g cinnamon, 14g notopterygium, 32g aloe vera, 38g Qingdai, 15g gallnut, 22g dogwood, 18g cistanche, 25g diffusa hedyotis, 25g flavescens, 12g polygala, 22g black plum, 68g coptis, plantain 20g of fruit, 16g of senna leaves, 15g of kudzu root, 25g of medlar, 35g of rehmannia root, 32g of Moutan cortex, 28g of licorice and 25g of Atractylodes macrocephala, mixed with 1600g of ethanol with an alcohol concentration of 90% and heated and refluxed for 3 times, and the obtained extract Merge, filter, concentrate under reduced pressure, remove 80% ethanol by mass percentage to obtain a concentrated solution, pass the concentrated solution through a 6LAB-8 macroporous adsorption resin column, and first elute with deionized water 4 times the volume of the resin column, and then use The alcohol concentration of 4 times of resin column volume is 95% ethanol elution, collects ethanol eluate...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for preventing and curing recurrent aphthae and a preparing method thereof, which comprises ingredients of upright ladybell root, evodia rutaecarpa, cinnamonum cassia, notopterygium root, aloe, indigo naturalis, Chinese gall, cornus officinalis, cistanche deserticola, oldenlandia diffusa, sophora flavescens, polygala tenuifolia, dark plum fruit, coptis chinensis, plantain seed, senna leaf, kudzuvine root, fructus lycii, dried rehmannia root, tree peony bark, licorice and bighead atractylodes rhizome. The traditional Chinese medicine for preventing and curing recurrent aphthae has the advantages of high efficiency and little toxic and side effect, being free of residue, drug resistance and environment pollution, quick effect, low cost and being worthy of popularization on prevention and treatment of recurrent aphthae.

Description

technical field [0001] The invention belongs to the technical field of medical engineering, in particular to a traditional Chinese medicine for preventing and treating recurrent aphthous ulcers. Background technique [0002] Recurrent aphthous ulcer is the recurrent oral ulcer (recurrent ulcer ROU) in Western medicine, also known as recurrent aphthous ulcer (RAU), which is isolated or multiple oral mucosal ulcers in any part of the oral mucosa irregularly or periodically. It is the most common oral mucosal disease in clinical practice. It is characterized by scattered superficial ulcers in the oral mucosa and local burning pain. It has the characteristics of localization, recurrence and self-healing. [0003] Although recurrent aphthous ulcers are not a serious or serious illness, and have no obvious systemic symptoms, they still affect daily life and work, especially when speaking or eating is very inconvenient, leading to eating disorders. Ambiguous, difficult to speak, e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/48A61K9/12A61K9/70A61P1/02
Inventor 戴忠明
Owner CHANGSHU HUAGANG PHARMA
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