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Medicament composition and application thereof

A composition and drug technology, applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of not eliminating the treatment factors and the great difference in the treatment effect, so as to stabilize the internal environment of the human body, prevent and treat progressive brain damage, and significantly The effect of curative effect

Active Publication Date: 2012-07-18
曹君
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In conclusion, rehabilitation does not eliminate the key case-treatment factor of progressive brain damage or developmental delay due to nutritional and metabolic imbalances
[0011] Most of the existing drugs are drugs for the treatment of children with cerebral palsy or central regulatory dysfunction, and the therapeutic effects vary greatly; there is no drug with obvious curative effect on children's brain development disorders caused by nutritional metabolism imbalance and other reasons

Method used

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  • Medicament composition and application thereof
  • Medicament composition and application thereof
  • Medicament composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] The preparation of Chinese and Western medicine composition of the present invention, process flow chart sees figure 1 :

[0085] 1. Extraction: Yizhi kernel 20kg, wolfberry 80kg, amomum 20kg, nutmeg 15kg, radish seed 40kg, boil in 800kg of water (100°C) and boil for 2 hours on low heat, extract the supernatant to the blending tank , and then put into 600kg of water to boil (100°C) and boil for 2 hours on low heat, and extract the supernatant to the blending tank; the supernatant is the raw material extract.

[0086] 2. Enzymatic hydrolysis: pump all the raw material extracts from the blending tank back to the extraction tank and boil (100°C) for 10 minutes, then add 800 grams of trypsin when it cools to 55-57°C, digest and decompose for 12 hours, and let it stand for stratification .

[0087] 3. Ingredients: Then, extract the raw material extract to the blending tank, heat to 100°C, add L-carnitine 36kg, taurine 2kg, zinc gluconate 50g, folic acid 10g, vitamin B1200g...

Embodiment 2

[0094] The product prepared by embodiment 1 is applied clinically, specifically as follows

[0095] One of the clinical observations:

[0096] Purpose of clinical observation: The conditioning effect of Yizhiren Drinking Liquid on the typical symptoms of brain development disorders in children under 0-3 years old.

[0097] Clinical contents and methods: 780 cases of observation objects were selected, and the treatment observation period was 12 weeks, and the Chinese and Western medicine composition (Yizhiren Decoction) of the present invention was orally administered. The ratio of nine typical symptoms in the case of 780 routine cases is shown in Table 1. After taking the medicine of the present invention, the nine typical symptoms before and after the comparison chart are shown in figure 2 .

[0098] Table 1 Proportion of nine typical symptoms in cases

[0099]

[0100] Observation conclusion: pharmaceutical composition of the present invention (Yizhiren drinking liqui...

Embodiment 3

[0114] One, the preparation of pharmaceutical composition of the present invention, process flow chart sees figure 1 , the preparation process is the same as in Example 1, except that the following reinforcing agent is added in the process of batching:

[0115] Pantothenic acid 10g, Nicotinamide 1g, Acetylcarnitine 300g, Propionylcarnitine 300g,

[0116] Lysine 1000g, Arginine 1000g, Histidine 1000g, Vitamin B12: 1g,

[0117] Coenzyme Q10: 300g, Ginkgo biloba extract 400g, resveratrol 200g, galantamine 80g, ferrous citrate 100g, calcium citrate 600g. (the Ginkgo biloba extract, resveratrol and galantamine are all purchased from Changsha Kanglong Biological Products Co., Ltd.)

[0118] Finally, 1000kg of the pharmaceutical composition was obtained, which was in the form of a light yellow liquid, a pure natural biological preparation. Dispense into 10mL soda-lime glass bottles.

[0119] 2. Toxicological experimental research:

[0120] 1. Experimental method:

[0121] 1.1 R...

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Abstract

The invention belongs to the field of medicaments for curing infantile brain development obstacle diseases and particularly relates to a medicament composition and application thereof. The medicament composition utilizes sharpleaf galangal fruit, lycium barbarum, fructus amomi, myristica fragrans and Chinese radish seed as raw materials, auxiliary materials including L-carnitine, taurine, zinc gluconate, folinic acid, vitamin B1, vitamin B2, vitamin B6, vitamin C, sodium ascorbate, potassium citrate and the like are added into supernate after water extraction of the raw materials to mix with the supernate, the mixture is evenly stirred, and then the mixture is filtered and filled to obtain the medicament composition. The medicament composition mostly adopts medicine edible ingredients andvitamin nutrition tonic ingredients and is free of toxic and side effect and clinically-proven effective in cure of the infantile brain development obstacle diseases through clinical prove.

Description

technical field [0001] The invention belongs to the field of drugs for treating children's brain development disorders, and in particular relates to a pharmaceutical composition and its application. Background technique [0002] Pediatric brain development disorders refer to non-progressive brain damage caused by various reasons and (or) progressive brain damage caused by nutritional metabolism imbalance and other reasons from before birth to before the child's brain is fully developed. General term for disease. [0003] The former is collectively referred to as cerebral palsy or central regulatory dysfunction in children, mainly manifested as central motor dysfunction and abnormal posture, and may be accompanied by mental retardation, epilepsy, hearing impairment, visual impairment, speech impairment, and behavioral and psychological abnormalities. The etiology of the latter is more complex and involves a wide range of pathophysiology. It is mostly caused by nutritional me...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P3/02A61P25/00
Inventor 王敏王益超曹君刘守
Owner 曹君
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