Compound glutaraldehyde disinfectant for body of dead person

A compound glutaraldehyde and disinfectant technology, applied in the direction of disinfectant, disinfection, biocide, etc., can solve the problem of low stability, achieve strong stability, high sterilization efficiency, and reduce surface tension

Active Publication Date: 2012-08-29
民政部一零一研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the 2% alkaline glutaraldehyde disinfectant product in binary packaging is the most common, and its stability is low; later, enh

Method used

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  • Compound glutaraldehyde disinfectant for body of dead person
  • Compound glutaraldehyde disinfectant for body of dead person
  • Compound glutaraldehyde disinfectant for body of dead person

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1: neutralizer identification test

[0020] The test strains were Staphylococcus aureus (ATCC 6538), Escherichia coli (ATCC 25922) and Candida albicans (ATCC 10231), and 6 parallel groups were set up, and the neutralizer identification test was carried out according to the suspension quantitative test procedure. Judgment of the results: Group 1 has aseptic growth or the number of bacteria is far less than that of Group 2; the number of bacteria in group 2 is significantly less than that of groups 3, 4, and 5; the number of bacteria in groups 3, 4, and 5 is similar, and the error rate is ≤ 10% ; Group 6 grew aseptically. It shows that the selected neutralizer and its concentration are appropriate, and the test is repeated 3 times.

[0021] The test shows that the PBS solution containing 1% glycine, 1% Tween 80, and 0.15% lecithin can effectively neutralize the residual effect of the disinfectant on the test bacteria. No adverse effects, in line with the requ...

Embodiment 2

[0025] Embodiment 2: Bacteria (fungus) quantitative killing test

[0026] In order to evaluate the killing effect of the disinfectant of the present invention on microorganisms, according to the disinfection technical specification (2002 edition), the quantitative killing test of bacteria and the killing test of fungi were carried out respectively. Strain selection: Staphylococcus aureus ATCC 6538 was used as the representative of pyogenic coccus in the bacterial propagule, Escherichia coli ATCC 25922 was used as the representative of intestinal bacteria in the bacterial propagule, and Candida albicans ATCC 10231 was used as the representative of pathogenic fungi. According to the specified use concentration and action time, repeat the test 3 times.

[0027] Result shows (table 2), when using disinfectant of the present invention to dilute 300 times, when action time is 3min, the killing rate to Staphylococcus aureus and Escherichia coli reaches 100%, kills logarithmic value ≥...

Embodiment 3

[0031] Embodiment 3: stability test

[0032] Accelerated test: Place the original sample in a constant temperature box at 54°C to 56°C for 14 days, keep the relative humidity ≥ 75%, and test the antibacterial or bactericidal performance of samples.

[0033]Experimental result shows (table 3), uses disinfectant of the present invention to dilute 100 times, and action time is 3min, and Staphylococcus aureus and Escherichia coli average killing rate can reach 100%, to the suspension quantitative killing rate of Candida albicans Up to 99.98%. This shows that after the accelerated test at 54°C, the disinfectant of the present invention can still meet the requirements of disinfection for its killing effect on microorganisms, which can be judged as passing. Therefore, the disinfectant of the present invention has strong stability, and the bactericidal or bacteriostatic effect of the product is valid for at least 1 year when stored at room temperature.

[0034] Table 3 Disinfectant ...

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Abstract

The invention provides a compound glutaraldehyde disinfectant for a body of a dead person, which mainly consists of the following ingredients by mass percent: 0.5 to 1.5 percent of glutaraldehyde, 0.2 to 0.5 percent of didodecyl dimethyl ammonium bromide, 0.2 to 0.5 percent of polyethylene glycol monooleyl ether, 0.5 to 1.5 percent of organic acid, 0 to 0.5 percent of essence and 95.5 to 98.6 percent of distilled water. The disinfectant is proved to have advantages of good stability, high sterilizing efficiency, no irritation and the like through a stability test, a microorganism killing test (including the neutralizer discrimination test) and on-site sterilization test in funeral parlour, is a high-efficient environment-friendly disinfectant, can be used for sterilizing the body of the dead person and associated environments as well as for sterilizing air and the surface of an ordinary object.

Description

technical field [0001] The invention relates to a chemical disinfectant, in particular to an efficient and environment-friendly compound glutaraldehyde disinfectant which can be applied to remains and related environments. Background technique [0002] As an important source of pollution in funeral places, the remains carry various pathogenic microorganisms, such as saprophytic bacteria and (conditional) pathogenic bacteria, etc., which will spread in the various processes of funeral services, resulting in air, object surfaces, remains surfaces, and workers in the environment. Microbial contamination, such as on the surface of hands, poses potential hazards to the health of funeral workers and bereaved households. The standard GB 19053-2003 stipulates the safety limit of pathogenic bacteria in various funeral places, and requires that the remains should be disinfected in time, and the funeral car, morgue, plastic surgery room, farewell hall, cremation room, etc. must be disi...

Claims

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Application Information

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IPC IPC(8): A01N35/02A01N33/12A01N25/22A01N25/30A01P1/00A01P3/00A61L9/012
Inventor 李玉光杨德慧王永阔刘国军姜思朋周雪媚李伯森钟照华林乐勋
Owner 民政部一零一研究所
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