The preparation method of benazepril hydrochloride tablet

A benazepril hydrochloride tablet and a technology for benazepril hydrochloride are applied in the field of preparation of benazepril hydrochloride tablets, and can solve the problems of inferior anti-sticking effect as magnesium stearate, burden on enterprises, and easy occurrence of sticking and flushing. , to achieve the effect of good physical isolation and ensure product quality
CN102697749BActive Publication Date: 2018-01-16SHANGHAI NEW ASIATIC PHARMA MINHANG
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHANGHAI NEW ASIATIC PHARMA MINHANG
Publication Date
2018-01-16

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Abstract

The present invention provides a kind of preparation method of benazepril hydrochloride tablet, by benazepril hydrochloride as the active ingredient of medicine, and pharmaceutical adjuvant filler, binding agent, disintegrant, lubricant magnesium stearate, The coating materials are combined into granules and made into tablets, which are characterized in that the lubricant magnesium stearate is added after the other components are granulated and coated, mixed and pressed into tablets. The invention can effectively physically separate the benazepril hydrochloride from the magnesium stearate, solves the problem that the related impurities of the variety rise too fast during storage, effectively controls the quality of the medicine, and has high use value.
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Description

Technical field

[0001] The invention relates to the field of pharmaceutical preparations, in particular to a preparation method of benazepril hydrochloride tablets for treating hypertension. Background technique

[0002] Hypertension is the most common disease affecting human health today and an important risk factor for cardiovascular and cerebrovascular diseases. Direct complications include cerebrovascular accidents, heart failure, renal failure, and coronary heart disease. Lowering blood pressure can significantly reduce the incidence of coronary heart disease and stroke. The prevention and treatment of hypertension has always been a very important research topic, and it is also a global concern for the development of antihypertensive drugs with better curative effects and less side effects. New drugs aiming at new and more effective targets and mechanisms of action have been developed and successively approved for marketing. Each type of antihypertensive drug has its own ch...

Claims

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