Unlock instant, AI-driven research and patent intelligence for your innovation.

Veterinary compound florfenicol injection

A technology of compound florfenib and injection, which is applied in the direction of medical formula, medical preparations containing active ingredients, digestive system, etc., can solve the problems of economic loss in pig production, restricting the development of pig industry, and ineffective effects, etc. To achieve the effect of uncontrollable dosage, long duration of drug effect and definite curative effect

Inactive Publication Date: 2012-11-21
SICHUAN DERUNTONG BIOTECH
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disease is widely prevalent in the pig industry. Clinically, these diseases sometimes appear alone, sometimes two or more mixed infections appear, which aggravates the disease. If appropriate measures are not taken in time, the development of the pig industry will be seriously restricted. , bringing huge economic losses to pig production
[0006] At present, veterinary clinical treatment of porcine digestive tract infectious diseases generally uses drugs such as gentamicin sulfate and enrofloxacin injection, but Escherichia coli and others are prone to drug resistance, and the effect is not obvious

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Veterinary compound florfenicol injection
  • Veterinary compound florfenicol injection
  • Veterinary compound florfenicol injection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Florfenicol 10g, andrographolide 2.5g, TMP1.5g, disodium oxalate tetraacetate 0.01g, sodium metabisulfite 0.1g, ethanol 28g, propylene glycol 50g, dimethylformamide 20g, monoethanolamine or Lactic acid or buffer is available as a pH adjuster.

[0032] The preparation method of preparation: take by weighing prescription amount florfenicol, andrographolide, TMP respectively, add in the injection solvent of 2 / 3 amount, stir and dissolve; Add antioxidant, disodium oxalate tetraacetate again, stir Dissolve; add solvent for injection to full amount, adjust pH value to 7.5, semi-finished product inspection, filter, potting, sterilize at 100°C for 30 minutes, cooling, light inspection, printing, packaging, finished product inspection, storage, ready to be obtained.

Embodiment 2

[0034] Florfenicol 15g, Andrographolide 3.5g, TMP2.5g, Disodium Oxalate Tetraacetate 0.01g, Sodium Bisulfite 0.1g, Sodium metabisulfite 0.1g, Ethanol 28g, Propylene Glycol 50g, 2-Pyrrolidone 10g , dimethylformamide 10g, monoethanolamine or lactic acid or buffer as a pH regulator for subsequent use.

[0035] Preparation method of the present invention: take by weighing prescription amount florfenicol, andrographolide, TMP respectively, add in the injection solvent of 2 / 3 amount, stir and dissolve; Add antioxidant, disodium oxalate tetraacetate again, Stir to dissolve; add solvent for injection to full amount, adjust pH value to 7, semi-finished product inspection, filter, potting, sterilize at 100°C for 30 minutes, cooling, light inspection, printing, packaging, finished product inspection, storage, ready to use .

Embodiment 3

[0037] Florfenicol 10g, andrographolide 5g, TMP3g, disodium oxalate tetraacetate 0.01g, sodium thiosulfate 0.1g, ethanol 28g, propylene glycol 40g, 2-pyrrolidone 10g, dimethylformamide 20g, monoethanolamine Or lactic acid or buffer as a pH regulator for later use.

[0038] Preparation method of the present invention: take by weighing prescription amount florfenicol, andrographolide, TMP respectively, add in the injection solvent of 2 / 3 amount, stir and dissolve; Add antioxidant, disodium oxalate tetraacetate again, Stir to dissolve; add solvent for injection to full amount, adjust pH value to 8, semi-finished product inspection, filter, potting, sterilize at 100°C for 30 minutes, cooling, light inspection, printing, packaging, finished product inspection, storage, ready to go .

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention aims to provide a veterinary compound florfenicol injection, which is used for efficiently treating porcine respiratory disease complex and porcine digestive tract disease. Each 100ml of veterinary compound florfenicol injection contains 10-30g of florfenicol, 1-5g of andrographolide, 1-3g of TMP (Trimethoprim), 0.1-0.2g of antioxygen, 0.01-0.02g of ethylenediaminetetraacetic acid disodium, and the balance of solvent for injection. The veterinary compound florfenicol injection is a composition of the florfenicol, the andrographolide and the TMP which have significant effects on the porcine respiratory disease complex, and is administrated through an injection way, the dosage is accurate, the absorption is quick, the blood concentration is high, the distribution is wide, the half-life period is long, the effective concentration maintenance time is long, and compared with the pesticide effect of the existing florfenicol injection and the herba andrographitis injection, the pesticide effect of the veterinary compound florfenicol injection is obviously enhanced.

Description

technical field [0001] The invention relates to a compound florfenicol injection for treating porcine respiratory syndrome and porcine digestive tract diseases. Background technique [0002] Porcine Respiratory Disease Syndrome (PRDC) is a disease characterized by reduced growth rate, reduced feed utilization, decreased appetite, coughing, and dyspnea. Although the overall mortality rate is not high, it can seriously affect the economic benefits of pig farming. [0003] At present, porcine respiratory disease syndrome has some new features. First, the pathogens manifested as mixed infection have changed compared with previous years. The pathogens are Mycoplasma pneumoniae, Reproductive and Respiratory Syndrome Virus (PRRSV), Circovirus Type 2 (PCV-2) and other infections, combined with secondary or mixed infections from other bacteria. The second is the change of the time of onset, which shows that pigs at all stages after weaning can suffer from the disease, that is, from...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/505A61K9/08A61P11/00A61P1/00A61P31/04A61P31/12A61K31/365A61K31/165
Inventor 陈益德胡学全周可刚刘亚何丽花
Owner SICHUAN DERUNTONG BIOTECH