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Medical hydrophilic lubrication coating of water system and preparation method thereof

A technology for lubricating coatings and water systems, applied to coatings, conduits, etc., can solve problems such as harming workers' health, polluting the environment, and complicated processes, and achieve the effects of reducing safety hazards, protecting the environment, and simplifying the preparation steps

Active Publication Date: 2013-03-20
宁波保税区安杰脉德医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] All of the above methods can obtain hydrophilic lubricating coatings, but some methods have the disadvantages of tedious steps and complicated processes.
In addition, it cannot be ignored that these methods all use organic solvent systems. The volatilization of these organic solvents not only brings hidden dangers in production, but also pollutes the environment and harms the health of workers.

Method used

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  • Medical hydrophilic lubrication coating of water system and preparation method thereof
  • Medical hydrophilic lubrication coating of water system and preparation method thereof
  • Medical hydrophilic lubrication coating of water system and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0028] Primer coating preparation: Weigh 20 g of water-based polyurethane resin (produced by DSM, with a solid content of 40%), 0.1 g of sodium lauryl sulfate, 1 g of carboxymethyl cellulose, and 20 g of deionized water, mix well, and statically Set aside for 24 hours after defoaming; obtain the bottom layer coating mixture.

[0029] Preparation of lubricating coating: Weigh 5g of polyvinylpyrrolidone, 5g of water-based polyurethane resin (solid content 40%), 0.1g of sodium lauryl sulfate, 40g of deionized water, mix well, let it stand for 24 hours for defoaming, and obtain a surface layer mixture liquid for use.

[0030] Immerse the PVC catheter in ethanol, ultrasonically clean it at 40KHz for 10 minutes, remove the dirt on the surface, and dry it; then soak it in the bottom coating mixture for 10 seconds, take it out and bake it at 70°C for 8 minutes until it is completely dry; use a scanning electron microscope The thickness of the underlying coating was detected to be 3 m...

Embodiment 2

[0033] Primer coating preparation: Weigh 20g of water-based polyacrylic resin (produced by DSM, solid content 40%), 0.15 of trisodium phosphate, 1.5g of carboxymethyl cellulose, 30g of deionized water, mix well, and let stand for 24 hours Stand-by after defoaming;

[0034] Lubricating coating preparation: weigh 6g of polyvinylpyrrolidone, polyacrylic acid resin (produced by DSM, solid content 40%) 6g, trisodium phosphate 0.15, deionized water 50g, mix well, let stand for 24 hours to defoam, wait use.

[0035] Immerse the latex catheter in ethanol, ultrasonically clean it at 45KHz for 7 minutes, remove the dirt on the surface, and dry it; then soak it in the bottom coating mixture for 10 seconds, take it out and bake it at 75°C for 20 minutes until it is completely dry; use a scanning electron microscope The thickness of the underlying coating was detected to be 1 micron. Then put it into the surface layer mixture and soak for 10 seconds, take it out and bake it at 80° C. for...

Embodiment 3

[0037] Primer coating preparation: Weigh 20 g of water-based bisphenol A epoxy resin (produced by DSM, solid content 40%), 0.15 g of polyoxyethylene alkyl ester, 1.5 g of carboxymethyl cellulose, and 30 g of deionized water , mix well, let it stand for 24 hours to defoam and set aside;

[0038] Lubricating coating preparation: Weigh 6g of polyvinylpyrrolidone, 2.5g of water-based polyurethane resin (produced by DSM, solid content 40%), 1g of water-based polyacrylic resin (produced by DSM, solid content of 40%), polyoxygen Vinyl alkyl ester 0.15g, deionized water 50g, mix well, let stand for 24 hours to defoam, set aside.

[0039] Immerse the silicone catheter in ethanol, ultrasonically clean it at 50KHz for 5 minutes, remove the dirt on the surface, and dry it; then soak it in the bottom coating mixture for 10 seconds, take it out and bake it at 90°C for 3 minutes until it is completely dry. The thickness of the undercoat layer was obtained to be 5 microns. Then put it into ...

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Abstract

The invention relates to a medical hydrophilic lubrication coating of a water system. The coating is characterized by comprising a bottom coating adhered to the surface of an instrument, and a lubricating coating adhered to the bottom coating, wherein the bottom coating comprises the components as shown in the specification in parts by weight: 20-50 parts of aqueous binder, 0.05-0.3 part of aqueous surfactant, 1-5 parts of aqueous thickener; and 10-50 parts of deion water; and the lubricating coating comprises the components as shown in the specification in parts by weight: 5-10 parts of aqueous macromolecule; 0.05-0.3 part of the aqueous surfactant; 1-5 parts of the aqueous binder and 40-80 parts of the deion water. Compared with the prior art, the medical hydrophilic lubrication coating does not need volatile solvents, and can be used for effectively reducing the surface friction resistance.

Description

technical field [0001] The invention relates to the field of medical equipment, in particular to a medical hydrophilic lubricating coating used in a water system of a polymer substrate and a preparation method thereof. Background technique [0002] With the development of medical technology, interventional therapy catheters are widely used in clinical treatment. Many devices that need short-term or long-term contact with human tissues, such as catheters and guide wires, will rub against the tissues in contact with them when they are inserted or pulled out, which may cause damage to the tissues and cause adverse reactions such as inflammation. Therefore, in order to reduce the risk of surgery and alleviate the pain of patients, lubricants such as silicone oil, paraffin oil, vaseline, etc. are often used to coat the catheter surface in clinical practice. These lubricant-treated instruments are not durable, do not lubricate well, and are not conducive to surgical procedures. ...

Claims

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Application Information

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IPC IPC(8): A61L29/08A61L29/14C08J7/04
Inventor 钟祥孙永富盛颖钟宁张明飞
Owner 宁波保税区安杰脉德医疗器械有限公司
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