Preparation method for trimethylamine oxide

Abstract

The invention discloses a preparation method for trimethylamine oxide. The technical scheme that hydrogen peroxide which is more than trimethylamine or stabilizing agent and / or initiating agent is added is adopted to enable the trimethylamine and the hydrogen peroxide to be reacted totally so as to avoid the raw material loss and to reduce the cost; the stabilizing agent is adopted in the reaction, so that the reaction system can be effectively stabilized, the excessive loss of reaction raw materials is controlled, and the yield is improved; the initiating agent is adopted in the reaction, so that the reaction activation energy can be reduced, and the reaction can be initiated at a lower temperature and can be implemented smoothly. The method reduces the raw material cost, reduces the equipment investment, largely decreases the acute reaction degree, stabilizes the reaction progress, and enables the reaction process to be easily controlled; and mother liquor can be recycled, so that the product yield and quality can be improved.

Description

technical field [0001] The invention relates to a method for preparing trimethylamine oxide. Background technique [0002] Trimethylamine oxide, also known as trimethylamine oxide, trimethyl-N-oxide, is the N-oxide formed by trimethylamine, chemical formula: (CH 3 ) 3 NO, the English name is Tri metlyl amine oxide, TMAO for short. Trimethylamine oxide is a colorless needle-like crystal, usually in the form of dihydrate. Easy to absorb moisture, soluble in water, insoluble in ether. Trimethylamine oxide exists widely in nature and is an endogenous substance naturally present in aquatic products, and it is also a characteristic substance that distinguishes aquatic products from other animals. [0003] As a new type, natural and safe animal feed additive, trimethylamine oxide dihydrate has obvious functions of attracting food and promoting growth, and has broad application prospects in aquaculture and animal husbandry. [0004] Its main purpose: [0005] 1) Feed additive;...

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Problems solved by technology

[0016] The disadvantages of this method are: the volume of the reactor required for the reaction is large, the energy consumption of the subsequent process of concentration and crystallization is high, and the separation and purification processes need to consume silver oxide; the auxiliary material hydrochloric acid is highly corrosive, and corrosion-resistant equipment is required; the separation and purification process is complicated. , it needs to consume organic solvents such as ethanol and methanol, causing serious pollution to the environment and high cost

Its disadvantages are: ①The melting point of hydrate (trimethylamine oxide dihydrate) is about 96°C, and the drying temperature of this method is 60°C-105°C exceeding the melting point of hydrate, which will melt the product, destroy the crystal structure, and change the properties of the product; 2. The 30% hydrogen peroxide aqueous solution used in this method, although the concentration is not high, hydrogen peroxide itself is a very volatile raw material, and it is easy to decompose into oxygen and water with the progress of reaction temperature increase. Reaction with equimolar hydrogen peroxide is likely to cause incomplete reaction of trimethylamine

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