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Traditional Chinese medicine rectal administration suppository for curing chronic prostatitis and preparing method thereof

A rectal drug delivery technology for chronic prostatitis, which can be used in pharmaceutical formulations, suppository delivery, and medical preparations containing active ingredients. It can solve the problems of poor treatment, slow effect, and low drug absorption rate, and improve connective tissue metabolism. , promote the disappearance and absorption, promote the effect of transformation and absorption

Inactive Publication Date: 2013-04-17
CHONGQING XUANNU BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The technical problem to be solved by the present invention is that the existing treatment methods, the treatment methods commonly used in Western medicine clinics include: antibiotics, intracapsular injection of the prostate, physical therapy, massage of the prostate, hot water sitz bath, etc., but a large amount of clinical practice shows that the above-mentioned The overall effect of the treatment method is not good, and other traditional Chinese medicine treatments, such as enemas and ointments for anorectal administration, have the disadvantages of unreasonable dosage forms, unscientific compatibility, inconvenient use, and poor treatment; Chinese medicine decoctions are taken orally, although there are some curative effects , but the curative effect is not good, the effect is slow, and the drug production cost is high, and the preparation cycle is long, and the drug absorption rate is low

Method used

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  • Traditional Chinese medicine rectal administration suppository for curing chronic prostatitis and preparing method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Embodiment 1: The production process of rectal administration suppository of the present invention is: Cynomorium 1000g, Poria cocos 1000g, Shichangpu 1000g, Toosendan 1000g, Safflower 1000g, Astragalus 1000g, Lietang 1000g, Yizhiren 1000g, Cornus officinalis 1000g , Hedyotis diffusa 1000g, Dandelion 1000g, Kochia scoparia 1000g, Plantago 1000g, Salvia miltiorrhiza 1000g, Phellodendron 1000g, Sophora flavescens 1000g, Prunella vulgaris 1000g, Myrrh 1000g, Patrinia 1000g, Scutellaria baicalensis 1000g, Radix paeoniae Rubra 1000g, Smilax tuckahoe 1000g, white fresh skin 1000g. Firstly, the crude drug is pulverized into a coarse powder, further pulverized, and passed through a 120-mesh sieve, so that the amount of fine powder passing through the 120-mesh sieve reaches 30%, and the fine powder a is collected through the 120-mesh sieve to obtain fine powder a; Coarse powder that cannot pass through a 120 mesh sieve is put into a multi-functional extraction tank for extractio...

Embodiment 2

[0057] Embodiment 2: the making process of the suppository of the present invention can also be: Cynomorium 1500g, Poria cocos 1500g, Shichangpu 1500g, Toosendan 1500g, Safflower 1500g, Astragalus 1500g, Lietang 1500g, Yizhiren 1500g, Cornus officinalis 1500g, Hedyotis diffusa 1500g, Dandelion 1500g, Kochia scoparia 1500g, Plantago 1000g, Salvia miltiorrhiza 1000g, Phellodendron 1000g, Sophora flavescens 1000g, Prunella vulgaris 1000g, Myrrh 1000g, Patrinia 1000g, Scutellaria baicalensis 1000g, Radix paeoniae Rubra 1000g, soil Poria cocos 1000g, white fresh skin 1000g. Blend, chop, soak. The soaked crude drug is heated and refluxed twice for 1 to 2 hours each time, and the two extracts are combined and left to stand. Then add 5-8 times the amount of 60-70% ethanol to the above-mentioned medicinal dregs extracted by water, heat and reflux to extract twice, each time for 1-2 hours, and combine the two extracts to stand still. Combine the above two extracts, concentrate the fil...

Embodiment 3

[0058] Embodiment 3: the preparation method of suppository of the present invention can also be: Cynomorium 1000g, Poria cocos 1000g, Shichangpu 1000g, Toosendan 1000g, Safflower 1000g, Astragalus 1000g, Lietang 1000g, Yizhiren 1000g, Cornus officinalis 1000g, Hedyotis diffusa 1000g, Dandelion 1000g, Kochia scoparia 1000g, Plantago 1500g, Salvia miltiorrhiza 1500g, Phellodendron 1500g, Sophora flavescens 1500g, Prunella vulgaris 1500g, Myrrh 1500g, Patrinia 1500g, Scutellaria baicalensis 1500g, Radix paeoniae Rubra 1500g, soil Mix 1500g of Poria cocos and 1500g of white fresh skin, add 5-10 times the amount of water to soak for 1-2 hours, extract twice; heat and extract for 1-2 hours, concentrate to extract, and become component 1; the remaining medicinal residues add 60 - Soak in 90% ethanol for 0.5-1.5 hours, extract twice, 1-2 hours each time, combine the extracts, filter, concentrate, filter with 80-160 mesh, and centrifuge the supernatant at 6000-10000 rpm, After ultrafil...

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Abstract

The invention provides a traditional Chinese medicine rectal administration suppository for curing chronic prostatitis, which is prepared from the following bulk drugs in part by weight: 10-20 parts of cynomorium songaricum, 10-20 parts of poria cocos, 10-20 parts of rhizoma acori graminei, 10-20 parts of szechwan Chinaberry fruit, 10-20 parts of safflower carthamus, 10-20 parts of astragalus mongholicus, 10-20 parts of orobanche coerulescens, 10-20 parts of fructus alpiniae oxyphyllae, 10-20 parts of dogwood, 10-20 parts of oldenlandia diffusa, 10-20 parts of dandelion, 10-20 parts of fructus kochiae, 10-20 parts of semen plantaginis, 10-20 parts of roots of red-rooted salvia, 10-20 parts of golden cypress, 10-20 parts of radix sophorae flavescentis, 10-20 parts of selfheal, 10-20 parts of myrrh, 10-20 parts of patrinia, 10-20 parts of scutellaria baicalensis, 10-20 parts of roots of common peony, 10-20 parts of rhizoma smilacis glabrae and 10-20 parts of cortex dictamni. The suppository enables drugs to be absorbed by rectal mucosal membrane and delivered to the affected site, has higher concentration inside the prostate in lesion, achieves ideal therapeutic effect, meanwhile avoids untoward effects of oral drug use and vein drug use, and further avoids the deficiencies that enemas are inconvenient to use and less prone to control the dosage, easily contaminate dresses and trousers as well as bed sheets and the like.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine rectal administration suppository for treating chronic prostatitis and a preparation method thereof. Background technique [0002] Chronic prostatitis is a common disease in adult males. According to statistics, patients with this disease account for 8% to 25% of urology outpatients. The prevalence of prostatitis in Asian men aged 20 to 79 is 2.7% to 8.7%. The unique anatomical structure of the prostate and the pathological characteristics of chronic prostatitis make it extremely difficult to treat. [0003] Chronic prostatitis is called "white turbidity" and "essence turbidity" in traditional Chinese medicine. "Suwen Tiaojing Lun": Shaoyang is in the spring, the guest wins, and even white urine. "Yuji Zhenzang Lun": The lower abdomen is injustice and hot, and the disease is white. "Origin of M...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61K9/02A61P13/08
Inventor 不公告发明人
Owner CHONGQING XUANNU BIOTECH
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