Wireless remote control photostimulation system for animals

Abstract

A wireless remote control photostimulation system for animals comprises an upper computer and a wearable photic stimulator which is wirelessly connected with the upper computer, wherein the photic stimulator comprises a control unit, a drive unit for driving a light emitting unit to emit light, the light emitting unit for emitting light to photically stimulate light sensation genetic cells and a power supply unit. An optical module is also arranged and connected with the light emitting unit through an optical coupling interface, and the light emitting unit, the optical coupling interface and the optical module are installed in an animal body. The photic stimulator of the wireless remote control photostimulation system for animals is in a wireless connection wear type, so that an experimental object is prevented from fracture due to winding which is easily caused by free moving in an experimental process, the experiment failure risk is reduced, and the system is reliable; and moreover, the light emitting unit is connected with the optical module and the optical coupling interface and then implanted into the animal body, accordingly, the deep nuclei of the animal can be deeply stimulated, and the photostimulation effectiveness is ensured.

Description

technical field [0001] The invention relates to medical equipment, in particular to a wireless remote control light stimulation system for animals. Background technique [0002] A major technical challenge in live animal experiments using optogenetics is the complexity of delivering external light sources into the animal's brain. The currently commonly used light source is a laser or LED light stimulator with a specific wavelength, which is implanted into the brain of an animal through an optical fiber connection. [0003] The laser itself is expensive and bulky, and the optical fiber is easy to twist and break when the animal moves freely, increasing the risk of experimental failure. The power supply of the LED light stimulator is also one of the difficulties. Generally, the coupling coil is used for wireless power supply through electromagnetic induction. After the alternating current is converted into direct current, it is stored in a supercapacitor to supply power for a...

AI Technical Summary

Problems solved by technology

[0003] The laser itself is expensive and bulky, and the optical fiber is easily entangled and broken during the free movement of the animal, which increases the risk of experimental failure

The power supply of the LED light stimulator is also one of the difficulties. Generally, the coupling coil is used for wireless power supply through electromagnetic induction. After the alternating current is converted into direct current, it is stored in a supercapacitor to supply power for a 1W LED, but still The problem is that the energy transmission efficiency is too low and unstable; in addition, although the LED is a cold light source, the heat generation of the driving circuit itself is an unavoidable problem, which can easily lead to heat accumulation and damage brain tissue

Another problem with using LEDs as stimulation light sources is that LEDs can be used to irradiate the cortex, but it is difficult to stimulate deep nuclei.

Images