Wireless Remote Control Light Stimulation System for Animals
A wireless remote control and light stimulation technology, applied in the field of medical devices, can solve problems such as damage to brain tissue, heat accumulation, and increase the risk of experimental failure, and achieve the effect of ensuring effectiveness, system reliability, and reducing the risk of experimental failure.
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[0026] "Optogenetic Technology" technology (Optogenetic Technology), using a viral vector (usually lentivirus or adenovirus) to introduce a gene (ChR2) that can encode a light-sensitive cation channel protein cloned from the green alga Chlamydomonas reinhardtii Expressed in a specific cell subpopulation, when this channel protein is stimulated by blue light with a wavelength of 472nm, Na + The entry of ions into the cell causes the depolarization of the cell membrane and excites the cell. In addition, there is another light-regulated chloride ion pump protein gene NpHR extracted from Natruonobacterium pharaonis, which is sensitive to yellow light with a wavelength of 593nm. Under the stimulation of yellow light, the chloride channel protein will make Cl - Entering the cell repolarizes the cell membrane, thereby returning the cell to rest, so that the use of alternating blue or yellow light can control cell activity at the level of specific cell subpopulations. This technolog...
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