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Traditional Chinese medicine extract and preparation method thereof

A technology of extracts and natural medicines, applied in drug combinations, pharmaceutical formulas, anti-tumor drugs, etc., can solve problems such as malnutrition, dehydration of patients, acid-base balance disorders, etc., and achieve obvious synergies, enhanced inhibition, and increased inhibition The effect of action

Inactive Publication Date: 2013-08-07
张宗升
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Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, etc., the incidence of chemotherapy-related diarrhea has increased year by year, and if active treatment is not carried out, it is easy to cause Dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc. in patients not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Therefore, effective treatment of chemotherapy-related diarrhea has become a An important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Traditional Chinese medicine extract and preparation method thereof
  • Traditional Chinese medicine extract and preparation method thereof

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Embodiment approach

[0030] The first step: preparation of various extracts

[0031] (1) Preparation of the concentrated extract of Astragalus Schisandra decocted in water

[0032] Take astragalus and schisandra according to the compatibility ratio of 1-5:1, add 10 times the amount of distilled water, soak for 1 hour, heat and decoct for 1 hour, filter with silk cloth, add 6 times the amount of distilled water to the dregs, soak, decoct, and filter in the same way. The two filtrates were mixed, heated and concentrated to a small volume, filtered with an ultrafiltration membrane, and dried under reduced pressure at 70°C to obtain the obtained product.

[0033] (2) Preparation of astragalus polysaccharide

[0034] Astragalus is crushed, saponin is extracted with 95% ethanol and dried, then distilled water is added, saturated lime water is added drop by drop, the pH value is adjusted, the material is left to stand for 10 minutes to moisten the material, microwave radiation is 1 minute, the interval ...

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Abstract

The present invention relates to a nature drug composition, a preparation method and uses of the nature drug composition in preparation of attenuation synergism drugs in cancer chemotherapy. The nature drug composition comprises an extract, milkvetch root polysaccharide and schisandra chinensis polysaccharide according to a ratio of 3-5:5-8:3-7, wherein milkvetch root and schisandra chinensis are subjected to water decoction concentration to obtain the extract. The composition provides good treatment effects for diarrhea related to cancer chemotherapy, and provides synergism effects for cancer chemotherapy.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of astragalus schisandra decocted concentrated extract, astragalus polysaccharide and schisandra polysaccharide, a preparation method of the natural medicine composition and the natural medicine composition Use of the drug in the preparation of a drug for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated diarrhea. In r...

Claims

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Application Information

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IPC IPC(8): A61K36/79A61K36/57A61P1/12A61P35/00A61K31/715
Inventor 张宗升
Owner 张宗升
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