Traditional Chinese medicinal composition for treating acute stage of gout and preparation method thereof

A composition and technology in the acute stage, applied in the field of medicine and health, can solve the problems of many side effects, intolerance of patients, large dosage, etc., and achieve the effects of low production cost, alleviation of joint swelling and pain, and no toxic and side effects.

Inactive Publication Date: 2014-04-23
LIUZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The current drug treatment for the acute phase of the disease is mainly colchicine, non-steroidal anti-inflammatory drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Embodiment 1 syrup

[0062] Atractylodes 0.7kg, Phellodendron 0.5kg, Coix seed 1.5kg, Achyranthes bidentata 0.7kg, Moutan bark 0.7kg, Salvia miltiorrhiza 0.7kg, Atractylodes macrocephala 1kg, Plantago 0.5kg, Lily 0.7kg, Gentiana 0.5kg.

[0063] Take all 10 medicinal materials, add water to extract twice, the amount of water added twice is 10 times and 8 times of the total weight of the medicinal materials respectively, and the extraction time of the two times is 2 hours and 1 hour respectively, the extracts are combined, filtered, and the filtrate is concentrated to 80 An extract with a relative density of 1.10 at °C. Adding syrup auxiliary materials sucrose, sorbic acid and water into the extract and stirring evenly to prepare the syrup.

Embodiment 2

[0064] Example 2 tablet

[0065] Atractylodes 2.5kg, Phellodendron 1.5kg, Coix seed 4.5kg, Achyranthes bidentata 2.5kg, Moutan cortex 2.5kg, Salvia miltiorrhiza 2.5kg, Atractylodes macrocephala 3kg, Plantago 1.5kg, Lily 2.5kg, Gentiana 1.5kg.

[0066] Take all 10 medicinal materials and extract them 3 times with 40% ethanol under reflux. The amount of ethanol each time is 10 times, 8 times and 4 times of the total amount of medicinal materials respectively. The extraction time is 3 hours, 2 hours and 1 hour respectively, and the extracts are combined. After filtering, the filtrate is concentrated to an extract with a relative density of 1.25 at 60°C, and supplementary materials such as starch, ethanol and talc are added to prepare tablets.

Embodiment 3

[0067] Embodiment 3 mixture

[0068] Atractylodes 1kg, Phellodendron 0.8kg, Coix seed 2kg, Achyranthes bidentata 1kg, Moutan bark 1kg, Salvia miltiorrhiza 1kg, Atractylodes macrocephala 1.5kg, Plantago 0.8kg, Lily 1kg, Gentiana 0.8kg.

[0069] Take all 10 medicinal materials, add water and extract 3 times, the amount of water added three times is equivalent to 12 times, 8 times, and 6 times the total weight of the medicinal materials, and the extraction time is 3 hours, 2 hours, and 1 hour respectively, and the extracts are combined and filtered. When the filtrate is concentrated to 70°C, the relative density is 1.20, add ethanol to make the alcohol content 40%, let it stand for 24 hours, filter, and the filtrate is concentrated to the extract with a relative density of 1.10 when the filtrate is concentrated to 70°C , add mixture auxiliary materials sucrose, ethyl ester, water, sorbic acid and stir evenly, add purified water until the total weight is 3 times of the total weigh...

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PUM

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating acute stage of gout and a preparation method thereof. The composition is prepared from rhizoma atractylodis, cortex phellodendri, coix seed, achyranthes bidentata, moutan bark, salviae miltiorrhizae, bighead atractylodes rhizome, plantain seed, lily and large-leaved gentian. The traditional Chinese medicinal composition is reasonable and creative in prescription, safe and effective, can be used for treating both symptoms and root causes, has the functions of clearing heat and cooling blood besides clearing heat and promoting diuresis, strengthening spleen to eliminate dampness, is more accordance to the pathogenesis in acute attack of gout, and can be used for more quickly relieving joint gall compared with existing traditional Chinese medicinal prescriptions with single effect of clearing heat and promoting diuresis.

Description

technical field [0001] The invention relates to the field of medicine and health, in particular to a traditional Chinese medicine composition for treating acute gout and a preparation method thereof. Background technique [0002] Gout is a crystal joint disease caused by the disorder of purine metabolism in the body or the decrease of uric acid excretion, which leads to the deposition of uric acid in the joints and other places in the body. In the acute phase, most patients develop symptoms in the middle of the night or early in the morning. At the beginning, most of them are single joints with inflammation, about half of which are the first metatarsophalangeal joint and the dorsum of the foot, followed by the heel, toe joints and other small and medium joints. The affected joints are red, swollen, hot and painful. , and accompanied by fever, increased white blood cells, accelerated erythrocyte sedimentation rate, severe pain at night, and people cannot sleep. [0003] The ...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P19/06
Inventor 郭玉荣李拥军张国峰
Owner LIUZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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