37 results about "Increased white blood cells" patented technology

Improved methods and pharmaceutical compositions are provided herein for mobilizing hematopoietic progenitor cells from bone marrow into peripheral blood, comprising the administration of an effective amount of an inhibitor of GTPases, such as Rac1 and Rac2 alone or in combination. Specifically, methods are disclosed for mobilizing hematopoietic stem cells into a subject's peripheral blood. In particular, embodiments of the method involve inhibition of both Rac1 and Rac2 GTPases to increase the numbers of hematopoietic stem cells into a subject's peripheral blood of a subject. The subject's blood can be processed and used to repopulate the destroyed lymphohematopoietic system of a recipient and may in the future be utilized to repair a variety of non-hematopoietic tissues. Therefore, hematopoietic stem cells mobilized into a subject's peripheral blood by the method of the invention is useful as a source of donor cells in bone marrow transplantation for the treatment of a variety of disorders, including cancer, anemia, autoimmunity and immunodeficiency. They can also be used for increasing white blood cell survival and for chemotherapy.

The invention discloses a novel extracting method of deer spleen extract and an application of deer spleen extract in immunity enhancement drugs. A traditional deer spleen extracting technology is improved, and centrifugation sediments are further extracted by a complex enzyme. Both polypeptide content and nucleotide content are improved by 30%. Moreover, the inosine ingredient occupies 8% of total nucleotide content in the extract, and the inosine content in the extract is improved. Meanwhile, the activity of the extract obtained by the method is improved by 20% than that of transfer factors extracted by the original technology for increasing the white blood cells.

Methods to improve hematopoiesis and increase white blood cell counts in subjects and patients using pyrimidine-based inhibitors of Bruton's tyrosine kinase (Btk) are disclosed.

The present invention relates to methods and compounds useful for increasing white blood cell levels in blood and bone marrow. Methods and compounds for increasing hematopoietic progenitor cells are also provided.

The present invention provides dithiolopyrrolone compounds of the general formula I, and their salts, wherein A is sulfur or carbon, and R1, R2, and R3 are selected from groups defined herein, and wherein when A is sulfur, then B is oxygen, and n=1 or 2, and when A is carbon, then B is oxygen or sulfur, and n=1. The compounds are useful for the prevention and treatment of microbial infections such as HIV infection, and for the treatment of blood disorders, such as neutropenia. In particular, the compounds are useful for the manufacture of medicaments for increasing white blood cells.

The invention relates to the field of organic synthesis and medicinal chemistry, in particular to a composition, a preparation method of the composition and an application of the composition to preparation of medicine for increasing white blood cells. According to the composition and the preparation method of the composition, pharmacology experiments show that the composition achieves the effect of increasing white blood cells, and has the value for developing the medicine for increasing white blood cells.

The invention discloses a qi-boosting, blood-boosting, whitening-boosting cream, which is prepared from the following raw materials in parts by weight: 3-10 parts of red ginseng, 3-10 parts of American ginseng, 15-60 parts of astragalus, and 10-20 parts of Ligustrum lucidum , Codonopsis 10-30 parts, Acanthopanax 10-30 parts, Atractylodes 10-30 parts, Taizishen 10-30 parts, Poria 10-30 parts, Rehmannia glutinosa 15-40 parts, Ganoderma lucidum 3-10 parts, Lycium barbarum 10 parts ~20 parts, 10-20 parts of angelica, 10-20 parts of raw hawthorn, 3-10 parts of donkey-hide gelatin, 10-20 parts of Eclipta, 10-20 parts of Rhodiola, and 100-400 parts of honey; the invention also discloses The preparation method of the above-mentioned nourishing qi and blood, strengthening the body and improving the whiteness and beauty cream; the patent of the present invention is mainly composed of commonly used drugs such as nourishing qi and blood, supporting righteousness, enhancing immunity, increasing white blood cells, etc.; High white blood cells, physical fitness, beauty and beauty.

The invention provides a method for extracting glycoprotein by utilizing a sea cucumber treatment blanching liquid and application thereof. The method for extracting the glycoprotein by utilizing the sea cucumber treatment blanching liquid comprises the following steps: (1) concentrating the sea cucumber treatment blanching liquid to obtain a concentrated liquid with the solid content of 15-45%; (2) drying the concentrated liquid to obtain a first solid powder; (3) adding the solid powder to 70-85% ethanol solution, stirring, desalting, removing saponin, and centrifuging or extraction filtering to collect a first solid insoluble substance; (4) repeatedly performing the steps (3) on the first solid insoluble substance for twice or three times to obtain a second solid insoluble substance without salt and the saponin; (5) adding the second solid insoluble substance to a 90-95% ethanol solution to stir, degreasing, extraction filtering to collect a third solid insoluble substance, and drying the third solid insoluble substance to obtain a second solid powder; (6) adding the second solid powder to purified water, heating and extracting to obtain an extract solution; (7) centrifuging the extract solution, removing sediment, filtering liquid supernatant, collecting filtrate, and drying the filtrate to obtain the glycoprotein with function of increasing white blood cells. The method for extracting the glycoprotein by utilizing the sea cucumber treatment blanching liquid is applied to preparation of medicines for increasing the white blood cells.

The invention provides an application of ursolic acid saponin and oleanolic acid saponin with a general formula I in the preparation of medicines for increasing leucocyte and / or blood platelet. The invention also provides a medicine combination with the chemical compound. The invention adopts the low-cost ursolic acid and oleanolic acid which is easily available from natural products and introduces monosaccharide and oligosaccharyl through structure modification. Pharmacology experiments prove that the invention can notably increase the leucocyte and / or the blood platelet.

The invention discloses α - Application of melanocyte-stimulating hormone in preparing medicine for treating elevated white blood cells and preventing radiation damage. The prevention of radiation damage refers to: melanocyte-stimulating hormone promotes the proliferation of bone marrow and spleen cells. The elevated leukocytes refers to leukopenia caused after chemotherapy. The prophylactic administration of the present invention can effectively improve the 30-day survival rate of mice irradiated with a lethal dose. Simultaneous prophylactic administration has obvious protective effect on chemotherapy-induced leukopenia and thrombocytopenia without obvious toxic and side effects.

The invention relates to a traditional Chinese medicine for treating tumors and a preparation method thereof, which is composed of the following components (according to weight ratio): fennel: windproof: white mustard seed: rhubarb: plantain seed: hanging golden lamp: almond: nightshade : Amaranthus: Sunflower seeds: Cantaloupe seeds: Water chestnut: Hawthorn: Red dates: Rock sugar: Walnuts: Soybeans: Sorghum: Peanuts: Red beans: Mung beans: Mushrooms: Fungus: Kelp: Seaweed = 1:2:1:2:2:2 :2:2:2:2:2:2:2:30:6:4:6:6:6:2:2:1:1:1:1. The advantages of the present invention are: the selection of raw materials and the preparation process are simple and easy, and the drugs are screened for the treatment of tumors in modern medicine, and have the functions of softening hard masses, clearing away heat and detoxification, promoting blood circulation and removing blood stasis, eliminating phlegm and eliminating tumors, and improving the body's immunity. It can effectively improve the immune function of the body, increase white blood cells, reduce the toxic reaction of radiotherapy and chemotherapy, improve clinical symptoms, improve the quality of life, and strengthen the body to eliminate cancer pain. It has achieved remarkable results in the treatment of various tumors and cancers. curative effect, and has important significance.