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Traditional Chinese medicinal preparation for treating Parkinson's disease and preparation method thereof

A traditional Chinese medicine preparation and a technology for Parkinson's disease, which are applied in the field of traditional Chinese medicine preparations for treating Parkinson's disease and their preparation, can solve the problems of multiple side effects of Parkinson's disease, are prone to drug resistance, cannot prevent the disease, and achieve short cure time, The effect of convenient administration and short course of treatment

Inactive Publication Date: 2014-11-19
HANGZHOU JINPEI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current treatment methods are mainly to improve the symptoms, but they can not prevent the progress of the disease. Moreover, the treatment of Parkinson's disease with western medicine has many side effects, a long course of treatment, unsatisfactory curative effect, easy to develop drug resistance, and even delay the disease.

Method used

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preparation example Construction

[0078] In order to solve the above-mentioned technical problems, the present invention also provides a method for preparing a Chinese medicine preparation for the treatment of Parkinson's disease, wherein, when the dosage form of the Chinese medicine preparation is a tablet, the preparation method comprises the following steps:

[0079] The first step is to mix the raw materials in the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 85-95% 2-4 times the mass of the mixture, heat and reflux for 1-3 hours, extract, and filter to obtain the first Extraction solution; add ethanol with an alcohol concentration of 85-95% relative to the mass of the medicinal residues that is 1-2 times the mass of the medicinal residues obtained by filtering, heat and reflux for 1-3 hours, extract, and filter to obtain a second extraction solution; The first extract and the second extract are combined, concentrated under reduced pressure to remove t...

Embodiment 1

[0097] Embodiment 1 Tablet of the present invention

[0098] The preparation process of the oral tablet of the present invention is as follows: get 2000g of bitter fennel, 1800g of Chuanbei, 2000g of gualou, 2500g of Smilax smilax, 1800g of bamboo leek, 2200g of Tianzhuhuang, 2000g of broad tendon vine, 2500g of Morus alba, and Badu powder 2200g, Peucedanum 1800g, Platycodon grandiflora 1900g, Lishi 2000g, Black berry 1800g, Perilla seed 1800g, Cinnamon 2500g, Angelica 1800g, Magnolia officinalis 2000g, Coltsfoot flower 2200g, Polygala 1800g, Mother-of-pearl 2000g, Cucumber 1800g, Gastrodia elata 2000g , rutabaga 2500g, earthworm 1700g, silkworm 2500g, Qiangui drunken vine 1800g, agarwood 2000g, knotweed 1800g, tangerine peel 2200g, lingxiaohua 2000g, aster 2200g and commelina 1800g;

[0099] The first step is to mix the raw materials in the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 85% that is 3 times the mass of the ...

Embodiment 2

[0103] Embodiment 2 Capsules of the present invention

[0104] The preparation process of the oral medicine capsule of the present invention is: take 2500g of bitter fennel, 2200g of Chuanbei, 2000g of Trichosanthes, 1800g of Smilax smilax, 3000g of bamboo leek, 2700g of Tianzhuhuang, 2500g of broad tendon vine, 2800g of Morus alba, and Badu powder 2000g, Peucedanum 2500g, Platycodon grandiflora 2000g, Lime stone 2000g, Black berry 1800g, Perilla seed 1900g, Cinnamon 2200g, Angelica 2500g, Magnolia officinalis 3000g, Coltsfoot flower 2500g, Polygala 1900g, Mother of pearl 2000g, Cumin paste 1700g, Gastrodia elata 2000g , Ruin 2200g, Dilong 2000g, Silkworm 2800g, Guizhou Drunken Soul Vine 1900g, Agarwood 2200g, Polygonum cuspidatum 1700g, Tangerine peel 2000g, Ling Xiaohua 2500g, Aster 1800g and Commelina 3000g;

[0105] In the first step, bitter gourd, Chuanbei, melon, sarsaparilla, bamboo leek, Tianzhuhuang, broad tendon rattan, Morus alba, Badu powder, Peucedanum, Platycodon...

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Abstract

The invention discloses a traditional Chinese medicinal preparation for treating Parkinson's disease and a preparation method thereof. The traditional Chinese medicinal preparation comprises the following raw medicinal materials: physalis angulate, Sichuan fritillary bulb, snakegourd fruit, sheath smilax, bamboo juice, tabasheer, tinospora sinensis merr, white mulberry root-bark, the seed of cowherb, radix peucedani, platycodon grandiflorum, chlorite schist, Japanese cayratia herb, fructus perilla, cinnamon, angelica sinensis, mangonolia officinalis, coltsfoot flower, polygala, mother-of-pearl, sand badger fat, gastrodia elata, hedge prinsepia nut, earthworm, batryticated silkworm, vigna vexillata, agilawood, giant knotweed, dried tangerine or orange peel, trumpet creeper, aster and dayflower. The traditional Chinese medicinal preparation disclosed by the invention has the beneficial effects that the preparation is of the effects of clearing heat, reducing phlegm, regulating vital energy, and calming liver wind, can be used for treating Parkinson's disease phlegm-heat wind symptoms and directly removing the focus with short treatment time and curing the disease without recurrence; the preparation is simple and convenient in manufacturing technology, low in toxic and side effect, convenient to administrate, easy to manufacture, low in cost, strong in targeted performance, short in treatment course, good in curative effect, and not liable to generate tolerance; the preparation can treat the disease based on syndrome differentiation from the holism concept.

Description

[0001] technical field [0002] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine preparation for treating Parkinson's disease and a preparation method thereof. [0003] Background technique [0004] Parkinson's disease (PD) is a common neurodegenerative disease, more common in the elderly, with an average age of onset of around 60 years old, and young Parkinson's disease with onset under the age of 40 is rare. The prevalence of PD among people over 65 years old in my country is about 1.7%. Most patients with Parkinson's disease are sporadic cases, and less than 10% of patients have a family history. The main pathological change of Parkinson's disease is the degeneration and death of dopamine (DA) neurons in the substantia nigra of the midbrain, which leads to a significant decrease in the content of DA in the striatum and causes the disease. The exact cause of this pathological chang...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/899A61P25/16A61K33/26A61K35/64A61K35/56A61K35/12
Inventor 苏琳
Owner HANGZHOU JINPEI TECH
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