Medicament for preventing and treating reproductive organ cancer and application thereof

A reproductive organ and drug technology, applied in the field of medicine, can solve problems such as low selectivity, damage to normal tissues and cells, and patient pain, and achieve the effect of promoting cell apoptosis and DNA repair

Inactive Publication Date: 2014-12-10
GUANGZHOU HYBRIBIO TECH
View PDF1 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The selectivity of chemical drugs and radiopharmaceuticals is not high. For patients with stage Ib-IIa, surgery is the last treatment, but the inability to completely remove the micrometastases becomes the root cause of postoperative recurrence.
The selectivity of chemical drugs and radiopharmaceuticals is not high. They can not only inhibit and kill tumor cells, but also damage normal tissues and cells in the body. There are obvious toxic and side effects in the treatment, and there are disadvantages such as drug resistance and high cost. However, there are quite a few Patients can not tolerate adverse reactions and give up treatment
However, physical therapy, such as laser, freezing, electrocautery and other treatments, often causes active diarrhoea, causing dull pain and discomfort in the lower abdomen, side effects such as vaginal discharge and even infection, and brings great physical and psychological pain to patients.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicament for preventing and treating reproductive organ cancer and application thereof
  • Medicament for preventing and treating reproductive organ cancer and application thereof
  • Medicament for preventing and treating reproductive organ cancer and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1. The preparation of gel

[0030] Prescription: Chloroquine Phosphate 150g

[0031] Carboxymethylcellulose 20g

[0032] Ethylparaben 0.2g

[0033] Glycerin 300ml

[0034] Water up to 1000ml

[0035]Full volume 1000ml

[0036] Preparation method: Take the prescribed carboxymethyl cellulose and add it to an appropriate amount of aqueous solution, then add the prescribed amount of glycerin, stir evenly until it is fully swollen. Take the prescribed amount of chloroquine phosphate, dissolve it with an appropriate amount of water, add it to the gel matrix in portions and stir, add the prescribed amount of ethylparaben, and add water to 1000ml.

Embodiment 2

[0037] Embodiment 2. Preparation of gel

[0038] Prescription: Chloroquine Phosphate 110g

[0039] Hydroxychloroquine Sulfate 50g

[0040] Sodium Alginate 15g

[0041] Ethylparaben 0.2g

[0042] Propylene glycol 300ml

[0043] Laurocaprazine 50ml

[0044] Triethanolamine Adjust pH to 7-8

[0045] Water up to 1000ml

[0046] Full volume 1000ml

[0047] Preparation method: Take the prescribed amount of sodium alginate, add propylene glycol while grinding until the ungelled matrix is ​​fully swollen, take laurocaprazine and add appropriate amount of water to mix, add the prescribed amount of chloroquine phosphate, hydroxychloroquine sulfate, and ethylparaben and stir After dissolving, add the gel base step by step, and add water to the full amount.

Embodiment 3

[0048] Embodiment 3. The preparation of ointment

[0049] Prescription: Chloroquine Phosphate 70g

[0050] Amodiaquine Hydrochloride 50g

[0051] Stearic acid 20g

[0052] Ethylparaben 0.1g

[0053] White Vaseline 20g

[0054] Liquid paraffin 160g

[0055] Triethanolamine 10g

[0056] Glycerin 50g

[0057] Lanolin 60g

[0058] Water up to 1000ml

[0059] Full volume 1000ml

[0060] Preparation method: take the prescribed amount of stearic acid, white vaseline, liquid paraffin, triethanolamine, glycerin, lanolin, ethylparaben, add appropriate amount of water and mix together to make an ointment base, take the prescribed amount of chloroquine phosphate and amodex hydrochloride Quinoquine is dissolved in water, added to the ointment base in portions, and fully stirred.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a medicament for preventing and treating a reproductive organ cancer. The medicament is characterized by containing one or more of salt-base compounds of chloroquine, hydroxychloroquine and amodiaquine. The medicament can be used for preventing and treating the reproductive organ cancer caused by human papillomavirus (HPV) infection.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicine capable of eliminating HPV virus and treating reproductive organ cancer caused by HPV infection and its application. Background technique [0002] The reproductive system is a general term for organs that produce germ cells, reproduce offspring, and secrete sex hormones to maintain secondary sexual characteristics. According to the different parts, it can be divided into two parts: internal genitalia and external genitalia. The male internal genitalia includes the testes, epididymis, vas deferens, ejaculatory ducts, prostate, seminal vesicles, and bulbourethral glands. Female genitalia consists of two parts: internal genitalia (ovaries, fallopian tubes, uterus, and vagina) and external genitalia (labia, clitoris, and vaginal vestibule). In addition, for female reproduction, there is also a very important organ breast, and canceration of these organs is genital canceration. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4706A61P35/00
Inventor 卢宏恭谢龙旭袁曼莉
Owner GUANGZHOU HYBRIBIO TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap