Components and preparation of vitamin C effervescent tablets
A technology for vitamins and effervescent tablets, applied in the field of medicine, can solve the problems of high local concentration, effervescent materials are easily restricted by the external environment, damage gastric mucosa, etc., and achieve the effects of low local concentration, smooth appearance, and high effervescent strength.
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Embodiment 1
[0013] A vitamin C effervescent tablet, characterized in that its component content is: vitamin C 2%-3%, citric acid 30%-35%, sodium carbonate / sodium bicarbonate (1:9) 20%-25%, Lactose / mannitol (10:1) 40%-45%, orange flavor 0.2%-0.5%, polyethylene glycol 4000 2%-5%.
Embodiment 2
[0015] A vitamin C, the preferred content of each component is: vitamin C 2%, citric acid 33.3%, sodium carbonate / sodium bicarbonate (1:9) 20%, lactose / mannitol (10:1) 41.7%, orange Flavor essence 0.2%, polyethylene glycol 4000 2.8%.
[0016] 1. Weigh the crushed vitamin C and citric acid, mix them evenly, add an appropriate amount of soft material containing 5% PVP absolute ethanol, granulate with a 20-mesh nylon screen, and dry at 45°C (the temperature should not be too high to prevent the deterioration of vitamin C ), 18 mesh whole grains.
[0017] 2. Weigh the crushed sodium carbonate / sodium bicarbonate, lactose / mannitol, and polyethylene glycol according to the prescription, mix well and add soft material containing 1% PVP anhydrous ethanol (soft material principle: hold lightly to form a ball , lightly press to disperse), granulate with 20-mesh nylon screen, dry at 60°C, and granulate with 30-mesh.
[0018] 3. Weigh and combine the above two kinds of granules in propor...
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