Hyaluronic-acid-containing hemostatic gauze and preparation method thereof

A technology of hyaluronic acid and hemostatic gauze, which is applied in the field of medicine, can solve the problems of complex waste treatment process, foreign body rejection, poor antibacterial and antibacterial ability, etc., and achieve good biocompatibility, no toxic side effects, and easy absorption Effect

Inactive Publication Date: 2015-04-01
ANHUI JIANYUAN MEDICAL APP & INSTR EQUIP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional hemostatic gauze is generally made of cotton, linen, etc., which has poor antibacterial and antibacterial ability, gauze fibers are easy to cause foreign body rejection and affect wound healing, and are easy to adhere to wound tissue during use, causing secondary damage. The generated waste has a complicated treatment process and is easy to pollute the environment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0021] Non-limiting examples of the present invention are as follows:

[0022] A hemostatic gauze containing hyaluronic acid, prepared from the following components by weight (kg):

[0023] Artemisia argyi 3, calendula 1.5, white fungus 3, peach gum 1.5, gelatin 10, hyaluronic acid 0.4, sodium alginate 3, carboxymethylcellulose sodium 4, sodium dihydrogen phosphate 0.4, edetate disodium 0.3 , polyvinylpyrrolidone 0.15, excipients 1.5, water 200;

[0024] Among them, the auxiliary materials are made of raw materials with the following weights (kg):

[0025] Soy lecithin 0.8, glycerin 3, polyethylene glycol 1.5, bletilla striata superfine powder 1.5, mannitol 3, chlorhexidine gluconate 1.5, vitamin C 1.5, water 18;

[0026] Preparation method of excipients:

[0027] Add soybean lecithin into water at 60°C and stir at 1000r / min for 1 hour, then add glycerin, polyethylene glycol, superfine powder of Bletilla striata and mannitol and stir for 15 minutes under the same conditions...

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Abstract

The invention discloses hyaluronic-acid-containing hemostatic gauze. The hyaluronic-acid-containing hemostatic gauze is characterized by being prepared from the following raw materials in parts by weight: 2-4 parts of folium artemisiae argyi, 1-2 parts of calendula, 2-4 parts of tremella, 1-2 parts of peach gum, 8-12 parts of gelatin, 0.3-0.5 part of hyaluronic acid, 2-4 parts of sodium alginate, 3-5 parts of sodium carboxymethylcellulose, 0.3-0.5 part of sodium dihydrogen phosphate, 0.2-0.4 part of ethylene diamine tetraacetic acid, 0.1-0.2 part of polyvinylpyrrolidone, 1-2 parts of auxiliary materials, and 200-250 parts of water. The soluble hemostatic gauze disclosed by the invention is collaboratively prepared from natural high polymer materials, is good in hemostatic function, is easy absorbed by human body, is good in biocompatibility, and is free from toxic and side effects; the soluble hemostatic gauze is capable of astringing to stop bleeding, and inhibiting bacteria and resisting inflammation by extracting and compounding the natural effective ingredients of calendula and folium artemisiae argyi, has a controlled-release function, effectively prolongs the action time, and achieves a better use effect.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a hemostatic gauze containing hyaluronic acid and a preparation method thereof. Background technique [0002] With the continuous advancement of medical technology, new medical materials and related technologies have been well developed. Among them, the development and improvement of hemostatic materials are conducive to improving the problems of surgical bleeding and bleeding, which is of great significance and has become a hot research topic in the field of medicine. Traditional hemostatic gauze is generally made of cotton, linen, etc., which has poor antibacterial and antibacterial ability, gauze fibers are easy to cause foreign body rejection and affect wound healing, and are easy to adhere to wound tissue during use, causing secondary damage. The generated waste has a complicated treatment process and is easy to pollute the environment. [0003] Soluble hemostatic gauze is a new ty...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/40A61L15/32A61L15/28A61L15/44A61L15/24A61L15/20A61L15/18
Inventor 朱来全
Owner ANHUI JIANYUAN MEDICAL APP & INSTR EQUIP
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