Preparation method of lemon extract, product and application of lemon extract

A technology of lemon extract and lemon juice, applied in the field of biomedicine, can solve the problems of liver and kidney function damage, obvious side effects, poor patient compliance, etc., and achieve the effects of kidney function protection, clear drug efficacy, and consistent drug efficacy.

Active Publication Date: 2015-04-22
HUAZHONG AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs are synthetic drugs, long-term use has obvious side effects, serious damage to liver and kidney functions, and poor patient compliance

Method used

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  • Preparation method of lemon extract, product and application of lemon extract

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preparation example Construction

[0021] The preparation method of lemon extract provided by the invention comprises the following steps:

[0022] (1) Squeeze the fresh lemon after peeling and deseeding, and separate the solid phase and the liquid phase to obtain clarified lemon juice and lemon pulp. The specific method is as follows:

[0023] After the peeled and deseeded fresh lemons are crushed, the liquid filtered through gauze is preferably filtered twice with three layers of gauze, and then the filtrate is centrifuged. The supernatant after centrifugation is the lemon juice. The precipitate and the filtered precipitate are combined to be the lemon puree.

[0024] (2) freeze-drying the lemon juice obtained in step (1) to obtain a water-soluble freeze-dried product; freeze-drying the lemon pulp obtained in step (1), crushing it into powder, and then using Ethyl acetate is extracted at -8°C to -2°C, and the solvent is removed from the extracted fat-soluble substance to obtain a fat-soluble substance powder...

Embodiment 1

[0032] The preparation method of lemon extract provided by the invention comprises the following steps:

[0033] (1) Squeeze the fresh lemon after peeling and deseeding, and separate the solid phase and the liquid phase to obtain clarified lemon juice and lemon pulp. The specific method is as follows:

[0034] Peel and remove the seeds of fresh Urik lemons, cut them into small pieces, put them into the juicer three times and squeeze them for 10 minutes. The lemon components obtained are filtered twice with 3 layers of gauze, and the filtrate is centrifuged at 5000rpm centrifuged under conditions for 15 minutes, the centrifuged supernatant is the lemon juice, and the centrifuged precipitate is combined with the filtered precipitate to become the lemon puree.

[0035] (2) After the lemon liquid obtained in step (1) is freeze-dried in a freeze dryer, it is a yellow mass sticking dry solid to obtain a water-soluble substance freeze-dried product; the lemon pulp obtained in step (1...

Embodiment 2

[0039] (1) Squeeze the fresh lemon after peeling and deseeding, and separate the solid phase and the liquid phase to obtain clarified lemon juice and lemon pulp. The specific method is as follows:

[0040] Peel and remove the seeds of fresh Urik lemons, cut them into small pieces, put them into the juicer three times and squeeze them for 10 minutes. The lemon components obtained are filtered twice with 3 layers of gauze, and the filtrate is centrifuged at 5000rpm centrifuged under conditions for 15 minutes, the centrifuged supernatant is the lemon juice, and the centrifuged precipitate is combined with the filtered precipitate to become the lemon puree.

[0041] (2) After the lemon liquid obtained in step (1) is freeze-dried in a freeze dryer, it is a yellow mass sticking dry solid to obtain a water-soluble substance freeze-dried product; the lemon pulp obtained in step (1) is , blown into powder with nitrogen, and then extracted with ethyl acetate at -2°C, adding 30ml of ethy...

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Abstract

The invention discloses a preparation method of a lemon extract, a product and application of the lemon extract. The preparation method comprises the following steps: (1) crushing peeled and seed-removed fresh lemons, and separating a solid phase from a liquid phase to obtain clear lemon liquid and lemon pulp; (2) performing freeze-drying treatment on the lemon liquid obtained in the step (1), thereby obtaining a water-soluble freeze-dried substance; performing freeze-drying treatment on the lemon pulp obtained in the step (1), crushing the lemon pulp subjected to freeze-drying treatment into powder, extracting by use of ethyl acetate at a temperature ranging from -8 DEG C to -2 DEG C, removing the solvent from the fat-soluble substance obtained after extraction, thereby obtaining fat-soluble substance powder; and (3) blending the water-soluble freeze-dried substance and the fat-soluble substance powder both obtained in the step (2). The lemon extract prepared by use of the method is applied to preparation of uric acid health food or medicines with an excellent effect, and also has a certain protection effect on the renal function.

Description

technical field [0001] The invention belongs to the field of biomedicine, and more specifically relates to a preparation method of lemon extract, its product and application. Background technique [0002] Uric acid is the final product of purine catabolism in nucleic acid, which is mainly excreted by the kidneys. Increased uric acid production or decreased excretion can cause uric acid accumulation and lead to hyperuricemia. [0003] With the improvement of living standards, changes in lifestyle and diet structure, and population aging, the incidence of hyperuricemia in my country is gradually showing a younger trend, and the number of patients is rising linearly. A large number of studies have shown that hyperuricemia can not only cause gouty arthritis, urinary tract stones, renal dysfunction, etc., but also has a close relationship with hypertension, left ventricular hypertrophy, insulin resistance, obesity, hyperlipidemia, and impaired glucose tolerance. It is an import...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A23L1/29A61P19/06A61P13/12A23L33/00
Inventor 马兆成王红静邓秀新
Owner HUAZHONG AGRI UNIV
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