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Composition of nervonic acid and bamboo leaf flavonoid as well as preparation method and application thereof

A technology of bamboo leaf flavonoids and nervonic acid, applied in application, food preparation, drug combination, etc.

Inactive Publication Date: 2015-05-06
彭秀英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Neural acid has good effects on the repair and nutrition of cranial nerves, the protection of brain tissue, and the prevention and treatment of cerebrovascular diseases. However, the adverse effect is that cardiovascular and cerebrovascular diseases usually occur together. There are many deficiencies in the overall control

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] Embodiment 1, nervonic acid bamboo leaf flavone emulsion and preparation method thereof

[0082] The prescription quantity is calculated by weight percentage and contains:

[0083] Nervous acid 0.05%~2.5%, preferably 1.5%,

[0084] Bamboo leaf flavonoids 0.5% to 5.5%, preferably 2.5%,

[0085] Lecithin 0.5~3.5%, preferably 0.2%,

[0086] Sweetener 0%~10%, preferably 0.015% sucralose,

[0087] Add purified water to 100%;

[0088] A preparation method comprising:

[0089] (1) Ingredients: weigh nervonic acid, bamboo leaf flavonoids, and sweeteners according to the formula, add them into purified water, stir, mix and disperse evenly, and set the volume to the required production volume;

[0090] (2) Emulsification: add lecithin to the liquid prepared in (1), and carry out emulsification operation for 5-35 minutes under the condition of liquid temperature of 35-65°C and stirring speed greater than 2000r / min, and let stand;

[0091] (3) Filling and sterilization: the emu...

Embodiment 2

[0093] Embodiment 2, ingot maple seed oil nervonic acid bamboo leaf flavone emulsion and preparation method thereof

[0094] The prescription quantity is calculated by weight percentage and contains:

[0095] Ingot maple seed oil with nervonic acid content ≥ 5.0% 0.5% to 10%, preferably 2.5%,

[0096] Bamboo leaf flavonoids 0.5% to 5.5%, preferably 3.5%,

[0097] Lecithin 0.5%~5%, preferably 3.5%,

[0098] Sweetener 0%~10%, preferably xylitol 7.5%,

[0099] Add purified water to 100%;

[0100] Preparation method: (1) Ingredients: Weigh ingot maple seed oil, bamboo leaf flavonoids, and sweetener according to the formula, add them into purified water, stir, mix and disperse evenly, and set the volume to the required production volume;

[0101] (2) Emulsification: add lecithin to the liquid prepared in (1), and carry out emulsification operation for 5-35 minutes under the condition of liquid temperature of 35-65°C and stirring speed greater than 2000r / min, and let stand;

[...

Embodiment 3

[0104] Embodiment 3, the soft capsule of nervonic acid bamboo leaf flavone and preparation method thereof

[0105] The prescription quantity is calculated by weight percentage and contains:

[0106] Nervous acid 0.05%~4.5%, preferably 5%,

[0107] Bamboo leaf flavonoids 0.5% to 5.5%, preferably 5%,

[0108] Add soybean oil to 100%;

[0109] The preparation method includes: weighing the prescribed amount of nervonic acid and adding soybean oil, stirring at 35-65°C to completely dissolve the nervonic acid in the soybean oil, then adding bamboo leaf flavonoids, stirring at a high speed to form a suspension, and then suspending The liquid is used as the content of the soft capsule, put it in a soft capsule molding machine, select the appropriate mold type, and use the molding method to wrap and compress it with gelatin film to form a soft capsule.

[0110] Among them, the preparation of the capsule material film, take 500g of gelatin, 80g of gum arabic, add 700g of distille...

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PUM

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Abstract

The invention provides a pharmaceutical composition containing nervonic acid and bamboo leaf flavonoid. The dosage form of the medicine is any pharmaceutically acceptable dosage form of medicines; the bamboo leaf flavonoid also comprises pharmaceutically acceptable salt or solvate; and nervonic acid and bamboo leaf flavonoid are combined at a weight ratio of (0.2-5):1. The preparation method comprises a step of mixing nervonic acid and bamboo leaf flavonoid with a pharmaceutically acceptable medicinal carrier to obtain any pharmaceutically acceptable dosage form of medicines. The invention further provides a collaborative application of the composition in protecting heart and cerebral vessels as well as heart and cerebral tissues, improving heart and cerebral ischemia and the like, and an application in reducing the risk of myocardial infarction, stroke or cardiovascular diseases.

Description

technical field [0001] The invention relates to a health product composition and a preparation method thereof, in particular to a composition of nervonic acid and bamboo leaf flavonoids, a preparation method and application thereof. The health product composition of the present invention includes but not limited to medicine, medical food, health food or functional food, common food and so on. Background technique [0002] Neural acid, cis-15-tetradecenoic acid, is a long-chain monounsaturated fatty acid, which is an important component of biological membranes in nervous tissue, a symbolic component of cerebroside medulla, cranial nerve fibers and nerve The core natural component of cells is also an essential nutrient for the growth, regeneration and function maintenance of nerve cells, especially brain cells, optic nerve cells, and peripheral nerves. It mainly exists in human brain tissue in the form of glycosphingolipids and sphingomyelin. It plays an important role in the...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K9/107A61K9/48A61P9/00A61P9/10A23L1/29A61K31/19A23L33/00
Inventor 张耿元王保红白东跃唐湘成
Owner 彭秀英
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