Traditional Chinese medicinal galactagogue for treating hypogalactia after cesarean delivery and preparation method of galactagogue

A technology of postpartum lactation deficiency and prolactin, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of aggravated maternal psychological pressure, low feasibility and compliance, and unfavorable milk secretion. To achieve the effect of no toxic side effects, no allergic reactions, and safe use

Inactive Publication Date: 2015-05-13
孙丽云
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many reasons for the lack of milk. Because the breastfeeding mother can not use drugs indiscriminately, the effect of massage and dietary supplements is not obvious, and the effect is slow, which invisibly aggravates the psychological pressure of the mother, and is not conducive to the secretion of milk, forming a malignant tumor. cycle
At present, postpartum lactation mainly relies on massage, prolactin soup, breast pump, acupuncture, traditional Chinese medicine and other methods, but the curative effect is uneven, the effect is slow, the prolactin cycle is long, the prolactin process is complicated, and the feasibility and compliance are low

Method used

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preparation example Construction

[0045] The present invention further provides a preparation method of the above-mentioned traditional Chinese medicine prolactin for treating post-cesarean hypogalactia, the dosage form of the traditional Chinese medicine prolactin is granule, which comprises the following steps:

[0046] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 4 to 6 times that of the mixture and 85% to 95% ethanol, heat to boiling and reflux for 3 to 5 hours, filter, and use percolation to remove Slowly percolate at a speed of 1-2ml per minute, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C, spray dry, spray dry The air inlet temperature of the machine is 160-175°C, and the outlet air temperature is 80-85°C, and then crushed into powder to make dry cream powder;

[0047] Step 2: Add 0.2-0.4 times of sucrose powder and 0.1-0...

Embodiment 1

[0060] Embodiment 1: the granule prepared by the present invention

[0061] Hydrangea Fangfeng 130g, Bergamot 170g, Gold Leaf 130g, Suanzaoren 210g, Paogan Ginger 220g, White Mustard Seed 180g, Magnolia Officinalis 200g, Cornus officinalis 170g, Ground Bamboo Shoots 200g, Toad Oil 240g, Red Hair Zouma 170g, Cherry Root 190g, Blood Wind rattan 230g, soil Codonopsis 210g, scissors rattan 190g and Lung sinensis 210g.

[0062] Its preparation method comprises the following steps:

[0063] Step 1: Mix all raw medicinal materials according to the above ratio, add ethanol with an alcohol concentration of 85% that is 5 times that of the mixture, heat to boiling and reflux for 4 hours, filter, and slowly percolate at a rate of 2ml per minute by percolation method , collect the percolation liquid, then concentrate under reduced pressure at 0.08Mpa to a paste with a relative density of 1.10 at 60°C, spray dry, the air inlet temperature of the spray dryer is 160°C, and the air outlet tem...

Embodiment 2

[0065] Embodiment 2: the capsule prepared by the present invention

[0066] Hydrangea Fangfeng 120g, Bergamot 180g, Gold Leaf 125g, Suanzaoren 230g, Paogan Ginger 200g, White Mustard Seed 160g, Magnolia Officinalis 210g, Dogwood 160g, Dizhu 180g, Toad Oil 220g, Red Hair Zouma 160g, Cherry Root 170g, Blood Wind rattan 210g, soil Codonopsis 200g, scissors rattan 170g and small lung sinensis 200g.

[0067] Its preparation method comprises the following steps:

[0068] The first step is to mix hydrangea fangfeng, bergamot, gold leaf, jujube seed, dried ginger, white mustard seed, and magnolia bark according to the above ratio, add 6 times the water to the mixture to extract the volatile oil, and paste the obtained volatile oil with β-cyclo Fine clathrate, the ratio of volatile oil to β-cyclodextrin is 1:5, stir for 80 minutes, temperature 40°C, get volatile oil clathrate, set aside; in addition, when the water extract is concentrated to 60°C, the relative density is 1.15~1.17 cl...

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PUM

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Abstract

The invention provides a traditional Chinese medicinal galactagogue for treating hypogalactia after cesarean delivery and a preparation method of the galactagogue. The traditional Chinese medicinal galactagogue consists of the following crude medicinal materials: ciliate leucas, bergamot, gold foil, wild jujube seed, baked dried ginger, semen brassicae, mangnolia officinalis, dogwood, lycopus lucidus, oviductus ranae, ardisia mamillata, cherry root, ventilago leiocarpa benth, radix campanumoeae, annular holostemma and spike aletris herb. The traditional Chinese medicinal galactagogue for treating hypogalactia after cesarean delivery disclosed by the invention has the following beneficial effects: the traditional Chinese medicinal galactagogue is safe in using, free from pain, free from toxic or side effect, free from allergic reaction, short in lactagogue cycle, high in curing rate and convenient in using. The traditional Chinese medicinal galactagogue, as a relatively ideal galactagogue, provides a safe, feasible, effective and highly compliant method for the lactagogue after cesarean delivery, and the galactagogue is simple and practical in preparation process.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine prolactin for treating hypogalactia after cesarean section and a preparation method thereof. Background technique [0002] Postpartum hypogalactia refers to the fact that a woman produces little or no milk after giving birth, which is not enough to feed her baby. It mostly occurs within two or three days to half a month after delivery, and may also occur throughout the lactation period. With the increase of cesarean section, the incidence of this disease has an upward trend. [0003] Studies have shown that breast milk is the best food for babies. Breast milk is rich and complete in nutrients and can meet the nutrition needs of babies in the first six months of age. In addition, the composition of breast milk will change with the baby's age and feeding time. Breast milk whey protein can prevent infants from gastroi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P15/14A61K35/65A61K33/24
Inventor 孙丽云李雪君高存良孟凡娟
Owner 孙丽云
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