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Foam dressing containing composite silver-zinc antibacterial material and preparation method of foam dressing

A technology of antibacterial materials and foam plastics, applied in medical science, bandages, absorbent pads, etc., can solve problems such as uneven distribution of drugs and hinder drug efficacy, reduce local bacterial proliferation or local metal poisoning, and protect the end Nervous, concentration-maintaining effects

Active Publication Date: 2015-06-03
SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the foaming agent prepared in this way, the drug is likely to be unevenly distributed in the foam or the drug is directly wrapped in the foam, which greatly hinders the efficacy of the drug.

Method used

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  • Foam dressing containing composite silver-zinc antibacterial material and preparation method of foam dressing

Examples

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preparation example Construction

[0041] 3) Preparation of foam dressings containing antibacterial materials: 10.0-20.0 parts by weight of polyether polyol, 0.5-1.5 parts by weight of stannous octoate, 0.5-1.4 parts by weight of dimethylethanolamine, and 0.5-1.8 parts by weight of silicon surfactant , 0.5-1.6 parts by weight of dichloromethane and 0.8-2.6 parts by weight of water are mixed, stirred quickly and evenly, added to the above-mentioned viscous prepolymer, stirred at high speed immediately, after mixing evenly, quickly poured into a foaming mold to foam, and matured for 24 - After 28 hours, the foam dressing containing the composite silver-zinc antibacterial material was obtained.

[0042] The second method for preparing the foam dressing containing the composite silver-zinc antibacterial material comprises the following steps:

[0043] 1) Preparation of composite silver-zinc antibacterial material;

[0044] 2) Preparation of prepolymer: Mix 40.0-53.0 parts by weight of dehydrated polyethylene glyco...

Embodiment 1

[0051] Embodiment 1: adopt method one to prepare the foam dressing containing composite silver-zinc antibacterial material

[0052] 1) Take 220g nanoscale Ag 2 O, 500g nano-ZnO, 280g nano-calcium carbonate, stir and mix evenly, place in a porcelain dish, put in a high-temperature furnace and burn at 800°C for 3 hours, pass through a 200-mesh sieve after cooling, and then obtain a composite silver-zinc antibacterial material ;

[0053] 2) Add 45.0g of dehydrated polyethylene glycol, 2.0g of glycerin, 31.5g of toluene diisocyanate and 1g of the above-mentioned composite silver-zinc antibacterial material into the three-necked bottle, heat and stir, and keep warm at 85°C for 80 minutes to obtain a viscous antibacterial material containing shape prepolymer;

[0054] 3) Take 15g of polyether polyol, 0.9g of stannous octoate, 1.1g of dimethylethanolamine, 1.0g of silicon surfactant, 1.0g of methylene chloride and 1.5g of deionized water, stir quickly and evenly, and add to the abo...

Embodiment 2

[0055] Embodiment 2: Adopt method two to prepare the foam dressing containing composite silver-zinc antibacterial material

[0056] 1) Take 220g nanoscale Ag 2 CO 3 , 500g nanoscale ZnO, 280g nanoscale diatomite, stir and mix evenly, place in a porcelain dish, put in a high temperature furnace and burn at 800°C for 3 hours, pass through a 200-mesh sieve after cooling, and the composite silver-zinc antibacterial Material;

[0057] 2) Add 45.0 g of dehydrated polyethylene glycol, 2.0 g of glycerin, and 31.5 g of toluene diisocyanate into the three-necked flask, heat and stir, and keep the temperature at 80°C for 120 minutes to obtain a viscous prepolymer;

[0058] 3) Get 15g polyether polyol, 0.9g stannous octoate, 1.1g dimethylethanolamine, 1.0g silicon surfactant, 1.0g methylene chloride and 1.5g deionized water and 1g of the above composite silver-zinc antibacterial material, quickly Stir evenly, add to the above viscous prepolymer, then add and immediately stir at high sp...

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Abstract

The invention provides a foam dressing containing a composite silver-zinc antibacterial material and a preparation method of the foam dressing. The foam dressing containing the composite silver-zinc antibacterial material comprises polyurethane foaming plastic and the composite silver-zinc antibacterial material, wherein the composite silver-zinc antibacterial material is adhered to the inside of the polyurethane foaming plastic, comprises the following raw materials in content: nano silver, nano zinc and a nano inorganic carrier; and the composite silver-zinc antibacterial material contains the following raw materials in percentage by mass: 10%-20% of silver and 20%-40% of zinc. The composite silver-zinc antibacterial material is dispersed into the foam dressing in a manner of foam molding or ultrasonic dipping together with foam. The foam dressing containing the composite silver-zinc antibacterial material is capable of effectively absorbing diffusate of the wound surface, and effectively inhibiting growth and breeding of staphylococcus aureus, pseudomonas aeruginosa and candida albicans.

Description

technical field [0001] The invention relates to a medical dressing and a preparation method thereof in the technical field, in particular to a medical dressing containing a composite silver-zinc antibacterial material and a preparation method thereof. Background technique [0002] The skin is the first immune barrier of human beings. After the skin is wounded, burned or ulcerated, the skin wounds are prone to produce exudate, pus, toxins and toxic products. The exudate contains a large number of inflammatory factors, proteases and Free radicals, etc. If these harmful substances stay on the skin surface for a long time, they will slow down the healing of the wound. [0003] Foam-type medical dressings are suitable for wound granulation stage. Foam-type dressings can absorb excess wound exudate, block external foreign bodies and some bacteria, protect exposed nerve endings, and relieve pain. At the same time, because the foam dressing keeps moist, it avoids the excessive evap...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/26A61L15/44A61L15/42
Inventor 刘磊高培军刘龙清马杰曾孔仙
Owner SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
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