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Starch-base plant empty capsules and preparation technology thereof

A plant hollow capsule and hollow capsule technology, which can be used in capsule delivery, food science, medical preparations of non-active ingredients, etc., can solve the problems of poor moisture retention of starch film, difficulty in industrialization, and difficulty in making strength, etc., to achieve inhibition The effect of starch retrogradation, improving mechanical properties, improving moisture retention and friability

Active Publication Date: 2015-07-22
湖南素囊健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] To sum up, although the prior art attempts to improve the water retention of starch by derivatizing and modifying the molecular structure of starch and introducing hydrophilic functional groups, strong intramolecular and intermolecular hydrogen are easily formed between starch molecules. Key, the starch film made of modified starch is still poor in moisture retention, brittle and brittle, and it is difficult to make capsules with high strength and resistance to filling
Therefore, although there are many patents, it is difficult to realize industrialization and form products

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Sol: First, pour 60 parts by weight of purified water into the sol tank and heat to 100 o C; subsequently, add the hydroxypropyl starch of 80 weight parts, 100 o C conditions, heat preservation and stirring for 60 minutes; then, turn off the heating device, add 5 parts by weight of liquid auxiliary materials (comprising 98wt% gum arabic and mannan, 2wt% sodium tartrate), stir and mix, and keep the temperature at 80 o Stir at C for 30 minutes; finally, add 0.1 part of propylene glycol, and stop the reaction after 5 minutes of airtight stirring, vacuumize at -0.04~-0.10MPa until no bubbles obviously emerge in the glue to obtain starch coarse glue; finally, open the sol Tank bottom valve, the glue is filtered through a 160-240 mesh filter bag and temporarily stored in the insulation barrel, and the viscosity of the glue is measured to be 2465mPa s;

[0038] Heat preservation: Add the glue obtained in the sol process to the glue barrel A and glue barrel B of the automatic ho...

Embodiment 2

[0044] Sol: First, pour 150 parts by weight of purified water into the sol tank and heat to 60 o C; subsequently, add the pregelatinized starch of 80 weight parts, at 60 o C conditions, insulation and stirring for 180 minutes; then, turn off the heating device, add 15 parts by weight of liquid auxiliary materials (comprising 98.5wt% carrageenan, trehalose and mannan, 1.5wt% sodium phosphate and sodium citrate) and 16 Parts of glycerin and triethyl citrate, stir and mix, keep the temperature at 60 o C and stirred for 60 minutes; finally, add 2 parts of sorbitol and propylene glycol, stop the reaction after 10 minutes of airtight stirring, and vacuumize under -0.04~-0.10MPa until no bubbles obviously emerge in the glue to obtain the starch coarse glue; finally , Open the seabed valve of the sol tank, the glue is filtered through a 160-240 mesh filter bag, and then temporarily stored in the insulation barrel, and the viscosity of the glue is measured to be 1186mPa·s;

[0045] H...

Embodiment 3

[0051] Sol: First, pour 100 parts by weight of purified water into the sol tank and heat to 80 o C; subsequently, add the carboxymethyl hydroxypropyl starch of 70 weight parts, at 80 o C conditions, heat preservation and stirring for 120 minutes; then, turn off the heating device, add 10 parts by weight of liquid auxiliary materials (including 97wt% carrageenan and gellan gum, 3wt% potassium citrate and sodium tartrate) and 7 parts of sorbitol and manna Alcohol, stir and mix, keep the temperature at 70 o Stir at C for 30 minutes; finally, add 1 part of PEG-400 and sodium lactate, and stop the reaction after 5 minutes of airtight stirring, and vacuumize at -0.04~-0.10MPa until no bubbles obviously emerge from the glue to obtain the coarse starch glue; Finally, open the seabed valve of the sol tank, the glue is filtered through a 160-240 mesh filter bag, and then temporarily stored in the insulation barrel, and the viscosity of the glue is measured to be 827mPa·s;

[0052] Hea...

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Abstract

The invention discloses starch-base plant empty capsules used in the fields of food, health care products and medicine, and a preparation technology of the empty capsules. The starch-base plant empty capsules mainly comprise starch, starch derivatives, water, a solidification system as well as other optional auxiliary materials of a humectant, a plasticizer, and the like, and from the preparation technology comprises the procedures of batching, solating, billet producing, cutting, embedding. Compared with the products in the prior art, the starch-based plant empty capsules has the advantages of being safe, reliable, high in friability and humectancy, convenient to store, and high in stability.

Description

technical field [0001] The invention relates to a starch-based vegetable hollow capsule used in the fields of food, medicine and the like and a preparation process thereof. Background technique [0002] Capsules have been made from animal-derived gelatin for nearly 200 years. In the past 100 years, various capsules made of gelatin have been sold well in the international pharmaceutical market for a long time. At the end of the last century, the outbreak of mad cow disease finally dragged gelatin capsules into an unprecedented crisis of confidence. In April 2012, the "poisonous capsule" incident that broke out in my country undoubtedly aggravated the crisis of trust in gelatin capsules. In addition, gelatin capsule itself also has many disadvantages, such as: it is easy to breed microorganisms and is fragile, and the high ambient humidity is easy to adhere to the drug, while the low ambient humidity is poor in flexibility and fragile; in addition, the gelatin molecular chai...

Claims

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Application Information

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IPC IPC(8): A61K9/48A61K47/36A23P1/04
Inventor 帅放文王向峰章家伟
Owner 湖南素囊健康科技有限公司
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