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A kind of preparation method of broccoli sprout extract capsule

A technology for broccoli sprouts and extracts, applied in the field of medicine, can solve the problems of low extraction yield, ignoring that the sulforaphane monomer is easily degraded, etc., and achieves the effects of simple operation, solving the scarcity of supply and saving costs.

Active Publication Date: 2018-07-31
WANNAN MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But above-mentioned two kinds of methods are all only for sulforaphane monomer, and above-mentioned two kinds of extraction methods all do not take into account that sulforaphane monomer is very easy to degrade under normal temperature, so extraction yield is low

Method used

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  • A kind of preparation method of broccoli sprout extract capsule
  • A kind of preparation method of broccoli sprout extract capsule
  • A kind of preparation method of broccoli sprout extract capsule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A preparation method of broccoli sprout extract capsule, comprising the following steps:

[0031] ⑴Wash the impurities on the surface of the seedling tray, soak it in 0.1% potassium permanganate solution for one hour, then rinse it and dry it for later use;

[0032] ⑵Put broccoli seeds in a seed soaking bag, soak the seeds and water at a mass ratio of 1:3 for 12 hours, change the water twice during this period to keep the seeds clean, rinse the seeds with pure water after soaking, and drain the water spare;

[0033] ⑶ Spread a layer of seedling paper on the bottom of the sterilized and dried seedling tray, wet the seedling paper with a watering can, spread the broccoli seeds evenly on the seedling paper, keep the seeds from overlapping, and spray the seeds with the watering can again after spreading. Seedling paper spray wet;

[0034] (4) Cut the clean gauze to be larger than the seedling tray, moisten it with water until it does not drip, cover it on the seedling tra...

Embodiment 2

[0051] Example 2: Analysis of the influence of different extraction conditions on the extraction rate of broccoli sprouts by response surface optimization method

[0052] Using Design-Expert 8.050b response surface analysis software, according to the Box-behnken center combination as the experimental design principle, through single factor experiments, the optimal value point is the center, and a horizontal value is taken for the upper and lower regions as the response surface experimental design level. Select the response value of the extraction rate of broccoli sprout extract, and select three factors that have a significant impact on the extraction rate: the solid-liquid ratio (X1) is 1:2, 1:3, 1:4; the enzymatic hydrolysis temperature (X2 ) at 20, 25, and 30°C; enzymatic hydrolysis time (X3) at 4, 6, and 8 hours for a three-factor three-level response surface analysis test.

[0053] The specific test steps are as follows:

[0054] (1) The seedling raising process conditio...

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Abstract

The invention discloses a preparation method of broccoli sprout extract capsules. The steps are: (1) After the broccoli seeds are cultivated without soil, the sprouts taken out for 3 days are dried, crushed and sieved at low temperature; (2) The sprout powder is added to Vit. C, use deionized water to adjust the ratio of material to liquid to 1:3, adjust the pH to 5, and make the cells broken by ultrasonic oscillation; (3) add acetone, oscillate under magnetic stirring, and fully enzymatically hydrolyze; (4) extract by ultrasonic oscillation, suction filtration, Rotary evaporation concentrates and freeze-dries to obtain broccoli sprout extract powder; (5) Broccoli sprout extract powder is prepared according to the ratio of 1 (powder): 4 (starch): 4 (sucrose): 1 (microcrystalline cellulose) Alcohol is used as a wetting agent to make granules; (6) capsules are filled to obtain broccoli sprout extract capsules. Compared with the prior art, the invention has simple operation and low cost, and the extract capsule contains 2 mg of active ingredient sulforaphane, which has anti-cancer, anti-oxidation and other functions, and has good application prospects.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a method for preparing broccoli sprout extract capsules. Background technique [0002] Broccoli contains a lot of glucosinolates. In the presence of water, after the cells are damaged, myrosinase can contact with glucosinolates and undergo hydrolysis reaction to produce isothiocyanates. , referred to as ITCs). Complete glucosinolates have almost no anticancer activity. When broccoli is harvested, processed, chewed, or plant hydrolyzed, plant cells are broken and endogenous myrosinase is released to hydrolyze glucosinolates into ITCs. The main component of ITCs is sulforaphane (SFN for short). SFN is abundant in broccoli, but the highest content of SFN is found in sprouts. SFN can inhibit the expression of phase I metabolic enzymes, reduce the metabolic activation of carcinogen precursors, and can also reduce foreign poisons, carcinogens and some active substances by up-regulating the e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/31A61K9/48A61P35/00A01C1/00
Inventor 刘晓平王天珩陈亚娟陈光海刘丁峰
Owner WANNAN MEDICAL COLLEGE