Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Bacillus subtilis preparation for spraying and application thereof

A technology of Bacillus subtilis and sprays, which is applied in aerosol delivery, medical preparations containing active ingredients, drug combinations, etc. It can solve the problems of poor film-forming effect, poor hemostatic effect, and single effect, and achieve accelerated speed , prevent infection aggravation, inhibit growth effect

Active Publication Date: 2015-09-09
H H T WHITE SWAN PHARMACY GRP
View PDF2 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] One of the objectives of the present invention is to solve the problem of low survival rate and poor film-forming effect when the Bacillus subtilis inoculum is applied to the treatment of burns in order to solve the problem of drug resistance in the existing treatment of burns, and to provide a Bacillus subtilis spray agent
[0010] Another purpose of the present invention is to solve the problem that the existing Bacillus subtilis inoculum has too single effect and poor hemostatic effect when applied to burn treatment, and provides a kind of application of Bacillus subtilis spray

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Bacillus subtilis preparation for spraying and application thereof
  • Bacillus subtilis preparation for spraying and application thereof
  • Bacillus subtilis preparation for spraying and application thereof

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0022] Specific embodiment one: this embodiment is a kind of Bacillus subtilis spray, and it is made up of Bacillus subtilis and matrix; The bacterial content of Bacillus subtilis in described Bacillus subtilis spray is 5.6~5.9×10 8 CFU / mL; the matrix is ​​composed of 85-94% nutrient solution, 5-10% glycerin and 1-5% dispersant by mass percentage, and the nutrient solution is composed of carbon source, nitrogen source, It is made by mixing inorganic salt and water, wherein the concentration of carbon source in the nutrient solution is 3-5mg / mL, the concentration of nitrogen source in the nutrient solution is 10-13mg / mL, and the concentration of inorganic salt in the nutrient solution is 0.05-0.1mg / mL The carbon source is composed of glucose, aloe polysaccharide and mint polysaccharide in a mass ratio of 1: (2-3): (2-3); the nitrogen source is soybean peptone, yeast powder, beef extract or soybean powder; the dispersant is sodium naphthalenesulfonate formaldehyde condensate or ...

specific Embodiment approach 2

[0033] Specific embodiment two: the difference between this embodiment and specific embodiment one is that the inorganic salt is composed of 0.05% by mass percentage of calcium chloride solution, 0.05% by mass percentage of manganese chloride solution, The magnesium sulfate solution with a mass percentage of 0.1% and the disodium hydrogen phosphate solution with a mass percentage of 0.2% are mixed in equal proportions. Other steps are the same as in the first embodiment.

specific Embodiment approach 3

[0034] Embodiment 3: The difference between this embodiment and Embodiment 1 or 2 is that the carbon source is composed of glucose, aloe polysaccharide and mint polysaccharide in a mass ratio of 1:2:2. Other steps are the same as those in Embodiment 1 or 2.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
Login to View More

Abstract

The invention relates to a preparation for spraying and application thereof, in particular to a bacillus subtilis preparation for spraying and application thereof. The problems to be solved are that existing burn treating medicines have tolerance, and a bacillus subtilis preparation is low in survival rate, poor in membrane forming effect and hemostatic effect and single in effect when applied to burn treatment. The bacillus subtilis preparation for spraying comprises bacillus subtilis, 85-94% of nutrient solution, 5-10% of glycerol and 1-5% of dispersant and is used for resisting bacterial infection of burns. The bacillus subtilis (BS224) preparation for spraying serves as a biological barrier and has an antibacterial effect on wound surfaces of the burns by implanting dominant bacteria into the wound surfaces to form a bacterial membrane rapidly and by the aid of biological antagonism.

Description

technical field [0001] The invention relates to a spray and its application. Background technique [0002] Burns are common sores both in peacetime and in wartime, and are generally treated with thermal burns (including hot liquids, such as water, soup, oil, etc., steam, high-temperature gas, flames, hot metal or plastic liquids and solids, such as molten steel, steel ingots, etc.) High temperature plastics, etc.) mainly. With the development of modern industrial and agricultural production technology, chemical and electronic burns show an increasing trend, which can cause batches of wounded in forest fires, flammable and explosive, fires in public places and modern wars. [0003] Burn infection is an important cause of wound deepening and sepsis, so prevention and control of wound infection is a content of burn research. Due to the tissue necrosis caused by burns, a good culture environment for the growth and reproduction of microorganisms is formed, and the local circula...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/742A61K9/12A61P17/02A61K31/715A61K31/717A61K31/734
Inventor 芦旭升杨慧冯媛肖颖于凯陈竹王巍董志玲吕雪
Owner H H T WHITE SWAN PHARMACY GRP
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com