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Universal oral abdominal and gastrointestinal tract image examination development additive and preparation method thereof

A technology for imaging aids and gastrointestinal tract, which is applied in the field of general-purpose oral imaging aids for abdominal gastrointestinal tract imaging examination and its preparation, which can solve the problems of increasing metabolic burden and increasing medical expenses, and achieves the goal of increasing the effective inspection window time, The effect of good contrast and improved retention time

Inactive Publication Date: 2015-11-25
SHANDONG NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, in order to clarify a certain diagnosis, it is usually necessary to combine multiple imaging techniques for comprehensive analysis. For this reason, patients need to use multiple types of contrast agents in a short period of time, which not only increases medical expenses, but also increases the metabolic burden of the body.

Method used

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  • Universal oral abdominal and gastrointestinal tract image examination development additive and preparation method thereof
  • Universal oral abdominal and gastrointestinal tract image examination development additive and preparation method thereof
  • Universal oral abdominal and gastrointestinal tract image examination development additive and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Example 1: Preparation of a universal oral imaging aid for abdominal gastrointestinal tract imaging

[0044] Raw material formula: 35 parts of mannitol, 50 parts of gum arabic, 2 parts of defoamer, 20 parts of maltodextrin, 0.08 parts of flavoring agent;

[0045] Wherein, the flavoring agent is composed of stevioside and lemon essence in a mass ratio of 1:1.

[0046] Preparation method: After all the substances are dried, use a dry powder mixer to disperse evenly and directly to make a dry suspension.

[0047] Method of use: Pour the bagged dry suspension into bottled purified water and shake well (the ratio of dry suspension to water is 1g:1ml), check immediately after oral administration.

[0048] Dosage: Varies depending on the inspection site:

[0049] (1) Dosage for stomach and duodenum: the general dosage for adults is 400-600ml, and the dosage for children is reduced to 200-400ml according to age;

[0050] (2) Dosage for the small intestine: about 1.5-2 times ...

Embodiment 2

[0052]Example 2: Preparation of a universal oral imaging aid for abdominal gastrointestinal tract imaging

[0053] Raw material formula: 30 parts of xylitol, 60 parts of xanthan gum, 0.2 part of defoamer, 30 parts of maltodextrin, 0.02 part of flavoring agent.

[0054] Wherein, the flavoring agent is composed of stevioside and lemon essence in a mass ratio of 1:1.

[0055] The preparation method and usage method are the same as in Example 1.

Embodiment 3

[0056] Example 3: Preparation of a universal oral imaging aid for abdominal gastrointestinal tract imaging

[0057] Raw material formula: 40 parts of xylitol, 40 parts of polyvinylpyrrolidone, 5 parts of defoamer, 10 parts of maltodextrin, and 5 parts of flavoring agent.

[0058] The preparation method and usage method are the same as in Example 1.

[0059] Wherein, the flavoring agent is composed of stevioside and lemon essence in a mass ratio of 1:1.

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Abstract

The invention discloses a universal oral abdominal and gastrointestinal tract image examination development additive. The universal oral abdominal and gastrointestinal tract image examination development additive is prepared from the following components in parts by weight: 30 to 40 parts of high-permeability contrast substance, 40 to 60 parts of expansion substance, 0.2 to 5 parts of defoaming agent, 10 to 30 parts of stabilizing agent, and 0.02 to 5 parts of corrigent, wherein the high-permeability contrast substance is one or two of mannitol or xylitol; the expansion substance is one or multiple of polyvinylpyrrolidone, Arabic gum or xanthan gum; the stabilizing agent is maltodextrin; the corrigent is one or two of lemon essence or stevioside. The invention also discloses a preparation method of the development additive. The universal oral abdominal and gastrointestinal tract image examination development additive is used for the contrasting display of gastrointestinal tracts (stomach, duodenum and jejunum), rectum and sigmoid colon (enema) during the B-ultrasonic, CT (computed tomography) and magnetic resonance examination, the comparison and description of abdominal solid organs, retroperitoneal structures and diseases, and the elimination of gas and artifacts.

Description

technical field [0001] The invention relates to a general-purpose oral imaging aid for abdominal gastrointestinal tract imaging examination and a preparation method thereof, belonging to the technical field of medical image diagnosis. Background technique [0002] Imaging examination technology has developed from the 1950s to today. It can perform effective clinical diagnosis on various solid organs, blood vessels and soft tissues of the human body, and has become a necessary means of medical examination. [0003] However, since the human gastrointestinal tract is a hollow organ, it is overlapping and tortuous, and the content of the gastrointestinal tract coexists with gas and liquid, resulting in chaotic echoes and signals, which are not only difficult to display in a natural state, but also cause damage to the surrounding organs. Occlusion and artifacts affect the diagnostic ability and application range of medical images. [0004] At present, there are many types of ima...

Claims

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Application Information

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IPC IPC(8): A61K49/22A61K49/04A61K49/06A61K47/26A61K47/32A61K47/36A61K47/46
Inventor 桂维玲姚建姚桂翔
Owner SHANDONG NORMAL UNIV
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