A kind of preparation method of oligomeric isomaltitol

Abstract

The invention belongs to the field of starch sugar derivative preparation, and particularly relates to a preparation method of high-quality oligomer isomaltitol, which is characterized by comprising the following steps: 1) 50-type isomaltooligosaccharide solution blending; 2) hydrogenation reaction; 3) decolorization and ion exchange; 4) chromatographic separation; and 5) concentration by evaporation to obtain the finished product. The 50-type saccharide has the characteristic of lower viscosity than the 90-type saccharide, and thus, has greatly lower stirring resistance in the hydrogenation process, thereby saving the stirring energy consumption. The chromatographic separation step is used for separating various alcohols and a small amount of saccharides, can obtain favorable separating effect under the conditions of low liquid viscosity and smaller water / material ratio, and has higher recovery rate.

Description

technical field

[0001] The invention belongs to the field of preparation of starch sugar derivatives, and in particular relates to a preparation method of oligomeric isomaltitol. Background technique

[0002] Isomaltooligosaccharide mainly contains isomaltose, isomaltotriose, panose, isomaltotetraose and other main components. Isomaltooligosaccharide is known as "bifidus factor" because it can improve constipation, reduce serum total cholesterol and low-density lipoprotein cholesterol, reduce physiological energy, and increase the number of bifidobacteria in the intestinal tract. One of the most popular functional oligosaccharides. Isomaltooligosaccharide has many excellent properties and physiological functional properties, but isomaltooligosaccharide is reducing and prone to Maillard reaction, which limits its application field.

[0003] Isomalt oligosaccharide is the reduction product of isomalto oligosaccharide. Compared with isomalt oligosaccharide, it has the charact...

Examples

Embodiment 1

[0018] 1) The 50-type isomaltooligosaccharide solution (the dry matter concentration is 35-55%, and the proportion of IMO in the total sugar is 45-55%) is slurried with sodium hydroxide, and the pH is adjusted to 7.0;

[0019] 2) Hydrogenation reaction, the temperature is controlled at 90°C, and then slowly raised to 110°C, the hydrogen pressure is 7MPa; the catalyst is skeleton nickel, and the addition amount is 6% of the dry matter; the stirring speed is 160r / min.

[0020] 3) decolorization, separation. Activated carbon decolorization, the amount of carbon added is 5%% of the dry matter, the decolorization temperature is 70°C, and the decolorization time is 60min; when the decolorization is performed, the decolorized feed solution is passed through a cation-anion-cation exchange column to remove ions and impurities.

[0021] 4) Chromatographic separation, using a strong acid resin, the feed concentration is 40%, the flow rate is 4L / h, and the feed liquid temperature is 50°C....

Embodiment 2

[0024] 1) The 50-type isomaltooligosaccharide solution (the dry matter concentration is 35-55%, and the proportion of IMO in the total sugar is 45-55%) is slurried with sodium hydroxide, and the pH is adjusted to 7.5;

[0025] 2) Hydrogenation reaction, the temperature is controlled at 100°C, and then slowly raised to 125°C, the hydrogen pressure is 8.5MPa; the catalyst is skeleton nickel, and the addition amount is 8% of the dry matter; the stirring speed is 190r / min r / min.

[0026] 3) decolorization, separation. For activated carbon decolorization, the amount of carbon added is 8% of the dry matter, the decolorization temperature is 80°C, and the decolorization time is 45 minutes; when decolorizing, the decolorized feed liquid is passed through a cation-anion-cation exchange column to remove ions and impurities.

[0027] 4) Chromatographic separation, using a strong acid resin, the feed concentration is 50%, the flow rate is 3L / h, and the feed liquid temperature is 60°C.

...

Embodiment 3

[0030] 1) The 50-type isomaltooligosaccharide solution (the dry matter concentration is 35-55%, and the proportion of IMO in the total sugar is 45-55%) is slurried with sodium hydroxide, and the pH is adjusted to 7.9;

[0031] 2) For hydrogenation reaction, the temperature is controlled at 110°C, then slowly raised to 140°C, and the hydrogen pressure is 10MPa; the catalyst is skeleton nickel, and the addition amount is 11% of the dry matter; the stirring speed is 220r / min.

[0032] 3) decolorization, separation. Activated carbon decolorization, the amount of carbon added is 10% of the dry matter, the decolorization temperature is 90°C, and the decolorization time is 30 minutes; when decolorizing, the decolorized feed solution is passed through a cation-anion-cation exchange column to remove ions and impurities.

[0033] 4) Chromatographic separation, using a strong acid resin, the feed concentration is 60%, the flow rate is 2L / h, and the feed liquid temperature is 70°C.

[00...

technical field

[0001] The invention belongs to the field of preparation of starch sugar derivatives, and in particular relates to a preparation method of oligomeric isomaltitol. Background technique

[0002] Isomaltooligosaccharide mainly contains isomaltose, isomaltotriose, panose, isomaltotetraose and other main components. Isomaltooligosaccharide is known as "bifidus factor" because it can improve constipation, reduce serum total cholesterol and low-density lipoprotein cholesterol, reduce physiological energy, and increase the number of bifidobacteria in the intestinal tract. One of the most popular functional oligosaccharides. Isomaltooligosaccharide has many excellent properties and physiological functional properties, but isomaltooligosaccharide is reducing and prone to Maillard reaction, which limits its application field.

[0003] Isomalt oligosaccharide is the reduction product of isomalto oligosaccharide. Compared with isomalt oligosaccharide, it has the charact...

Examples

Embodiment 1

[0018] 1) The 50-type isomaltooligosaccharide solution (the dry matter concentration is 35-55%, and the proportion of IMO in the total sugar is 45-55%) is slurried with sodium hydroxide, and the pH is adjusted to 7.0;

[0019] 2) Hydrogenation reaction, the temperature is controlled at 90°C, and then slowly raised to 110°C, the hydrogen pressure is 7MPa; the catalyst is skeleton nickel, and the addition amount is 6% of the dry matter; the stirring speed is 160r / min.

[0020] 3) decolorization, separation. Activated carbon decolorization, the amount of carbon added is 5%% of the dry matter, the decolorization temperature is 70°C, and the decolorization time is 60min; when the decolorization is performed, the decolorized feed solution is passed through a cation-anion-cation exchange column to remove ions and impurities.

[0021] 4) Chromatographic separation, using a strong acid resin, the feed concentration is 40%, the flow rate is 4L / h, and the feed liquid temperature is 50°C....

Embodiment 2

[0024] 1) The 50-type isomaltooligosaccharide solution (the dry matter concentration is 35-55%, and the proportion of IMO in the total sugar is 45-55%) is slurried with sodium hydroxide, and the pH is adjusted to 7.5;

[0025] 2) Hydrogenation reaction, the temperature is controlled at 100°C, and then slowly raised to 125°C, the hydrogen pressure is 8.5MPa; the catalyst is skeleton nickel, and the addition amount is 8% of the dry matter; the stirring speed is 190r / min r / min.

[0026] 3) decolorization, separation. For activated carbon decolorization, the amount of carbon added is 8% of the dry matter, the decolorization temperature is 80°C, and the decolorization time is 45 minutes; when decolorizing, the decolorized feed liquid is passed through a cation-anion-cation exchange column to remove ions and impurities.

[0027] 4) Chromatographic separation, using a strong acid resin, the feed concentration is 50%, the flow rate is 3L / h, and the feed liquid temperature is 60°C.

...

Embodiment 3

[0030] 1) The 50-type isomaltooligosaccharide solution (the dry matter concentration is 35-55%, and the proportion of IMO in the total sugar is 45-55%) is slurried with sodium hydroxide, and the pH is adjusted to 7.9;

[0031] 2) For hydrogenation reaction, the temperature is controlled at 110°C, then slowly raised to 140°C, and the hydrogen pressure is 10MPa; the catalyst is skeleton nickel, and the addition amount is 11% of the dry matter; the stirring speed is 220r / min.

[0032] 3) decolorization, separation. Activated carbon decolorization, the amount of carbon added is 10% of the dry matter, the decolorization temperature is 90°C, and the decolorization time is 30 minutes; when decolorizing, the decolorized feed solution is passed through a cation-anion-cation exchange column to remove ions and impurities.

[0033] 4) Chromatographic separation, using a strong acid resin, the feed concentration is 60%, the flow rate is 2L / h, and the feed liquid temperature is 70°C.

[00...

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