Traditional Chinese medicine gel for treating keratitis and preparation method and application thereof

A technology of keratitis and traditional Chinese medicine, which is applied in the field of medical applications, can solve the problems of damaging the body's immune mechanism, preventing virus reproduction, and damaging corneal tissue, so as to achieve the effects of no toxic and side effects, repairing the damaged immune system, and enhancing the body's resistance

Inactive Publication Date: 2016-03-09
刘可
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the clinical treatment methods for herpes simplex virus keratitis mainly include: focus debridement, suitable for superficial cases, the principle is to remove infected cells and viruses through physical or chemical methods, including mechanical debridement, chemical debridement, etc. Debridement, freezing debridement, photoinactivation therapy, debridement of the lesion can only remove infected cells but not prevent virus reproduction, may damage the corneal epithelial basement membrane and stromal layer, and promote the development of lesions to the deep, cryotherapy has no effect on the vitality of HSV Antiviral drugs, such as iodinidine, cytarabine, trifluo...

Method used

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  • Traditional Chinese medicine gel for treating keratitis and preparation method and application thereof
  • Traditional Chinese medicine gel for treating keratitis and preparation method and application thereof
  • Traditional Chinese medicine gel for treating keratitis and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A traditional Chinese medicine gel for treating keratitis, which is composed of the following raw materials in parts by weight: 30 parts of honeysuckle, 30 parts of Budisma, 20 parts of Fangfeng, 20 parts of Hagi chinensis, 10 parts of Gongluomu, 10 parts of Vitex, 8 parts of nepeta, 6 parts of loofah, 6 parts of red peony, 3 parts of Caulis Spatholobus, and 3 parts of star anise gold plate.

[0025] The preparation method of the Chinese medicine gel for the treatment of keratitis, the specific steps are as follows:

[0026] (1) take each raw material according to parts by weight;

[0027] (2) Add water to decoct the raw material medicine twice, add 6 times of water for the first time, decoct for 2 hours, filter out the medicinal liquid, continue adding 6 times of water to the medicinal residue, decoct for 2 hours, filter out the medicinal liquid, and discard the medicinal residue Remove; the filtrates are combined and concentrated to a relative density of 110 to obtai...

Embodiment 2

[0031] A traditional Chinese medicine gel for treating keratitis is composed of the following raw materials in parts by weight: 32 parts of honeysuckle, 32 parts of Budisma, 22 parts of Fangfeng, 22 parts of Hagi chinensis, 12 parts of Gongluomu, 12 parts of Vitex, and Vitex 9 parts of mustard ears, 7 parts of loofah, 7 parts of red peony, 4 parts of Caulis Spatholobus, and 3.5 parts of star anise gold plate.

[0032] The preparation method of the Chinese medicine gel for the treatment of keratitis, the specific steps are as follows:

[0033] (1) take each raw material according to parts by weight;

[0034] (2) Add water to decoct the raw material drug for two times, add 6.5 times of water for the first time, decoct for 2.5 hours, filter out the medicinal liquid, continue to add 6.5 times of water to the medicinal residue, decoct for 2.5 hours, filter out the medicinal liquid, and The slag was discarded; the filtrates were combined and concentrated to a relative density of 11...

Embodiment 3

[0038] A traditional Chinese medicine gel for treating keratitis is composed of the following raw materials in parts by weight: 35 parts of honeysuckle, 35 parts of Budisma, 25 parts of Fangfeng, 25 parts of Hagi, 15 parts of Gongluomu, 15 parts of Vitex, and Vitex 10 parts mustard ears, 8 parts loofah, 8 parts red peony root, 5 parts Caulis Spatholobus, 4 parts star anise gold plate.

[0039] The preparation method of the Chinese medicine gel for the treatment of keratitis, the specific steps are as follows:

[0040] (1) take each raw material according to parts by weight;

[0041](2) Add water to decoct the raw material drug for two times, add 7 times of water for the first time, decoct for 3 hours, filter out the medicinal liquid, continue adding 7 times of water to the medicinal residue, decoct for 3 hours, filter out the medicinal liquid, and discard the medicinal residue Remove; the filtrates were combined and concentrated to a relative density of 113 to obtain a clear ...

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Abstract

The invention discloses traditional Chinese medicine gel for treating keratitis and a preparation method and application thereof. The raw materials of the Chinese medicine gel for treating the keratitis include honeysuckles, flos buddlejae, divaricate saposhnikovia roots, securinega suffruticosa, mahoniae caulis, fructus viticis, herba schizonepetae, loofah sponges, common peony roots, caulis spatholobi and fatsia japonica. In preparation, a moisturizing agent, a pH regulating agent and a buffer agent are added, wherein the moisturizing agent is glycerin or propylene glycol, and the buffer agent is sodium citrate/a citric acid buffer pair, a phosphate buffer pair, a tris-hydrochloric buffer pair or a glycine-triethylamine buffer pair. The traditional Chinese medicine gel achieves the keratitis treating purpose through transdermal absorption of the medicines, rapidly eliminates symptoms including photophobia, tearing, aching pain and the like caused by the keratitis, repairs a damaged immune system, improves the body resistance, fundamentally treats the keratitis, directly acts on the eyes, is free of toxic and side effects and provides a new choice for clinical keratitis treatment and alleviation of the symptoms caused by the keratitis.

Description

technical field [0001] The invention relates to the technical field of medical application, in particular to a traditional Chinese medicine gel for treating keratitis, a preparation method and application thereof. Background technique [0002] Herpes simplex virus keratitis is the most serious common corneal disease at present, and it has a clear rising and aggravating trend in recent years. Due to recurrent attacks and increasing number of severe cases, it seriously threatens visual function, so strengthening the research on this disease has become an urgent problem to be solved in ophthalmology. The clinical manifestations of this disease are complicated. In addition to the typical shape of branches, maps and disc-shaped corneal lesions, there are also some atypical clinical changes, which bring great difficulties to diagnosis and treatment. Each type not only has unique clinical characteristics, but also has different pathogenesis and treatment principles. The various ty...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61K9/06A61K47/10A61P27/02A61P31/22
CPCA61K36/85A61K9/0048A61K9/06A61K36/238A61K36/25A61K36/29A61K36/355A61K36/42A61K36/47A61K36/486A61K36/538A61K36/56A61K36/65A61K36/71A61K47/10A61K2236/331A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 刘可
Owner 刘可
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