Degradable male genital organ patch composite material with biological elasticity and preparation method thereof

A technology for male genitalia and composite materials, which is applied in the field of male genitalia patch composite materials and its preparation, can solve the problems of silicone displacement, uneven autologous fat, foreign body sensation, etc., and achieves easy bending, slow degradation, good elasticity and The effect of biocompatibility

Inactive Publication Date: 2016-09-07
李世荣 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In recent years, with the development of society and the improvement of living standards, more and more men hope to become more confident through male reproductive plastic surgery. However, traditional genital filling materials such as

Method used

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  • Degradable male genital organ patch composite material with biological elasticity and preparation method thereof
  • Degradable male genital organ patch composite material with biological elasticity and preparation method thereof
  • Degradable male genital organ patch composite material with biological elasticity and preparation method thereof

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Embodiment 1

[0040] The technical scheme of the present invention is described in detail by taking the submucosa of the small intestine as the raw material of the biofilm matrix.

[0041] The detailed preparation process of the biodegradable bioelastic male genital patch composite material is as follows:

[0042] 1) Preparation of biofilm: mechanically remove the serosa layer, serosa layer, and muscular layer of the porcine small intestine to obtain the submucosa of the small intestine, and wash it repeatedly for later use;

[0043] 2) Degreasing: Soak the obtained porcine small intestinal submucosa in a mixed solution of methanol and chloroform with a volume ratio of 1:1 for 12 hours, and rinse with deionized water for 3 times;

[0044] 3) Decellularization: place the degreased porcine small intestinal submucosa material in physiological saline containing trypsin and EDTA for 48 hours at 4°C, and wash it repeatedly with deionized water for 3 times; the mass percentage of trypsin and EDTA ...

Embodiment 2

[0050] The technical scheme of the present invention is described in detail by taking pig pericardium as the biofilm matrix raw material.

[0051] The detailed preparation process of the biodegradable bioelastic male genital patch composite material is as follows:

[0052] 1) Take the biofilm: mechanically separate the heart of the pig from the pericardium, scrape off the fat on the pericardium, and wash it repeatedly to get a nearly transparent pericardium for later use;

[0053] 2) Degreasing: soak the obtained pericardium in a mixed solution of methanol and chloroform with a volume ratio of 1:1 for 12 hours, and rinse with deionized water for 3 times;

[0054] 3) Decellularization: the pericardium material after degreasing was placed in physiological saline containing trypsin and EDTA for 48 h at 4° C., washed repeatedly with deionized water for 3 times; the mass percentage of trypsin and EDTA was 0.05%; the physiological saline is a sodium chloride solution with a mass fr...

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Abstract

The invention discloses a degradable male genital organ patch composite material with the biological elasticity and a preparation method thereof. The patch composite material is prepared from biomembrane substrate powder and a biodegradable high-molecular polymer according to the mass ratio of 4:1-1:4 and obtained through the steps that the biomembrane substrate powder and the biodegradable high-molecular polymer are dissolved into a solvent to prepare a solution, and the solution is poured into a mold to be molded and then taken out of the mold to be subjected to freeze drying, wherein the biomembrane substrate powder is powder prepared through the step that a biomembrane is degreased, decellularized and subjected to antigen removal. The composite material is good in mechanical property, easy to bend and capable of being metabolized. A natural biomembrane is adopted as a biomembrane substrate, and the biomembrane substrate has the good elasticity, biocompatibility and bioactivity; the adopted high-molecular polymer material is biodegradable high molecules and has the excellent slow degradation advantage.

Description

technical field [0001] The invention belongs to the field of material technology, and in particular relates to a degradable bioelastic male genital patch composite material and a preparation method thereof. Background technique [0002] In recent years, with the development of society and the improvement of living standards, more and more men hope to become more confident through male reproductive plastic surgery. However, traditional genital filling materials such as silica gel and autologous fat are metabolized quickly after filling. There will also be silica gel displacement, foreign body sensation, and uneven autologous fat, which make many patients and doctors feel that there is a fly in the ointment. Contents of the invention [0003] In view of this, the object of the present invention is to provide a biodegradable male genital patch composite material with bioelasticity and a preparation method thereof. The male genitalia patch composite material provided by the i...

Claims

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Application Information

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IPC IPC(8): A61L27/36A61L27/18A61L27/58A61B17/00
CPCA61L27/3604A61B17/00A61B2017/00862A61B2017/00893A61B2017/00964A61L27/18A61L27/362A61L27/3629A61L27/3687A61L27/58A61L2400/16A61L2430/34
Inventor 王秋玉李世荣李晓格
Owner 李世荣
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