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Pharynx-heat-clearing and larynx-moistening soft capsule preparation and method for preparing pharynx-heat-clearing and larynx-moistening soft capsule preparation

A soft capsule preparation, throat clearing and throat moisturizing technology, applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of unsuitable tablet dosage forms, slow drug effect, and difficulty in removing lesions, etc. , to achieve the effect of easy to swallow, neat appearance, easy to store and carry

Inactive Publication Date: 2016-09-28
WANNAN MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Throat disease is a common multiple disease. In modern medicine, pharyngitis is generally divided into chronic pharyngitis and acute pharyngitis. Acute pharyngitis generally uses non-drug treatments such as lasers, microwaves, or atomized inhalation, or uses chemical drugs. However, for chronic pharyngitis, although non-drug treatment or chemical drug treatment can improve the symptoms, it is difficult to remove the cause of the disease, and it is easy to relapse after the symptoms are relieved.
[0003] In recent years, there have been many throat-clearing and throat-moistening products of Chinese patent medicines, such as watermelon cream throat tablets, grass coral buccal tablets, etc. These Chinese patent medicine products have a certain effect on alleviating the symptoms of chronic pharyngitis. However, currently on the market Throat-clearing and throat-clearing products are mostly tablets, and their medicinal effects are slow. For those traditional Chinese medicine extracts that contain more volatile components and are bitter in taste, tablet dosage forms are not suitable. Throat-clearing and moisturizing preparations with beautiful shape, uniform dispersion, stability, accurate device, high bioavailability, and the ability to mask the bitterness of traditional Chinese medicine are urgently needed in the market

Method used

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  • Pharynx-heat-clearing and larynx-moistening soft capsule preparation and method for preparing pharynx-heat-clearing and larynx-moistening soft capsule preparation
  • Pharynx-heat-clearing and larynx-moistening soft capsule preparation and method for preparing pharynx-heat-clearing and larynx-moistening soft capsule preparation
  • Pharynx-heat-clearing and larynx-moistening soft capsule preparation and method for preparing pharynx-heat-clearing and larynx-moistening soft capsule preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] A clear throat and throat soft capsule preparation, which is mainly made of the following materials and parts by weight:

[0045]

[0046] The preparation method of the above-mentioned Qingyan Moistening Soft Capsule is:

[0047] (1) Preparation of traditional Chinese medicine extract: 10 parts of honeysuckle, 15 parts of forsythia, 10 parts of licorice, 5 parts of dandelion, 5 parts of mosquitoes, 4 parts of wolfberry, 4 parts of sclerotium, 3 parts of lotus seed heart, 2 parts of bitter melon root Mix with 2 parts of spearmint, add water 20 times the mixing weight, reflux and extract for 7 hours, filter, repeat this process 2 to 3 times, combine the filtrate, concentrate and dry the filtrate to obtain the Chinese medicine extract powder.

[0048] (2) Add 60 parts by weight of Chinese medicinal material extract powder to 25 parts of sesame oil, stir and heat to 95°C, until completely dissolved;

[0049] (3) Add 2 parts of olive oil to the product of step (1), and stir evenly; ...

Embodiment 2

[0053] A clear throat and throat soft capsule preparation, which is mainly made of the following materials and parts by weight:

[0054]

[0055] The preparation method of the above-mentioned Qingyan Moisturizing soft capsule preparation is:

[0056] (1) Preparation of traditional Chinese medicine extract: 15 parts of honeysuckle, 10 parts of Forsythia, 15 parts of licorice, 3 parts of dandelion, 3 parts of Mosquito, 6 parts of Lycium barbarum, 3 parts of Strawberry, 3 parts of Lotus Seed Heart, 3 parts of Bitter Melon Root Mix with 3 parts of spearmint, add a 95% ethanol solution of 25 times the mixed weight, reflux for 6 hours, filter, repeat this process 2 to 3 times, combine the filtrate, concentrate and dry the filtrate to obtain a traditional Chinese medicine extract powder.

[0057] (2) Add 90 parts by weight of Chinese medicinal material extract powder to 30 parts of sesame oil, stir and heat to 100°C, until completely dissolved;

[0058] (3) Add 1 part of olive oil to the pro...

Embodiment 3

[0062] A clear throat and throat soft capsule preparation, which is mainly made of the following materials and parts by weight:

[0063]

[0064] The preparation method of the above-mentioned Qingyan Moisturizing soft capsule preparation is:

[0065] (1) Preparation of traditional Chinese medicine extract: 5 parts of honeysuckle, 10 parts of forsythia, 5 parts of licorice, 5 parts of dandelion, 8 parts of mosquito, 6 parts of medlar, 2 parts of sclerotium, 4 parts of lotus heart, 4 parts of bitter melon Mix with 4 parts of spearmint, add 25 times the mixed weight of 75% ethanol aqueous solution, reflux and extract for 5 hours, filter, repeat the process 2 to 3 times, combine the filtrate, concentrate and dry the filtrate to obtain the Chinese medicine extract powder.

[0066] (2) Add 80 parts by weight of Chinese medicinal material extract powder to 25 parts of sesame oil, stir and heat to 105°C, until completely dissolved;

[0067] (3) Add 4 parts of olive oil to the product of step ...

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Abstract

The invention discloses a pharynx-heat-clearing and larynx-moistening soft capsule preparation and a method for preparing the pharynx-heat-clearing and larynx-moistening soft capsule preparation. The soft capsule preparation is prepared from the following substances in parts by weight: 60 to 90 parts of traditional Chinese medicinal extract, 20 to 30 parts of sesame oil, 1 to 4 parts of olive oil, 2 to 4 parts of snow pear juice and 1 to 4 parts of white granulated sugar; the traditional Chinese medicinal extract is formed by extracting the following traditional Chinese medicinal materials of flos lonicerae, fructus forsythiae, radix glycyrrhizae, herba taraxaci, semen oroxyli, fructus lycii, boat-fruited scaphium seed, lotus plumule, radix momordicae charantiae and whole herb of mentha spicata. The pharynx-heat-clearing and larynx-moistening soft capsule preparation is scientific in the compatibility of components, is easy to take, has the advantages of being attractive in appearance, uniform and stable in dispersion, accurate in placement and high in bioavailability, moreover, can be used for covering ingredients, with bitter and astringent properties and flavors, in traditional Chinese medicines, has an obvious curative effect on chronic pharyngitis and laryngitis, and can be used for enhancing the anti-infectious immunity of a respiratory tract when being taken for a long time.

Description

Technical field [0001] The invention relates to a clear throat and throat soft capsule preparation and a preparation method thereof. Background technique [0002] Throat disease is a common multiple disease. In modern medicine, pharyngitis is generally divided into chronic pharyngitis and acute pharyngitis. Acute pharyngitis is generally treated with non-drug treatment methods such as laser, microwave, or atomized inhalation, or chemical drugs Treatment, but for chronic pharyngitis, although non-drug treatment or chemical treatment can improve the symptoms, it is difficult to remove the cause of the disease, and it is easy to relapse after the symptoms are relieved. [0003] In recent years, many Chinese patent medicines for clearing throat and moisturizing throat products, such as watermelon cream moisturizing throat tablets, grass coral lozenges, etc., have been effective in relieving symptoms of chronic pharyngitis. However, the current market Most throat clearing and throat pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61K9/48A61P11/04
CPCA61K36/355A61K9/4858A61K36/185A61K36/288A61K36/42A61K36/484A61K36/534A61K36/62A61K36/634A61K36/73A61K36/815A61K2300/00
Inventor 熊延靖李怀斌董群陈京刘辉杨成蔡天鑫刘安臧开林单东方杨雅倩方毓楠
Owner WANNAN MEDICAL COLLEGE