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A kind of traditional Chinese medicine composition for treating kidney cancer

A technology of composition and traditional Chinese medicine, which is applied in the direction of drug combination, medical formula, antineoplastic drugs, etc., can solve the problems of lost operation opportunities, long-term treatment difficulties, and unsustainable curative effect, so as to avoid recurrence and metastasis, reduce adverse reactions, and improve The effect of medicine

Inactive Publication Date: 2019-04-09
MUDANJIANG MEDICAL UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Surgical treatment is the most commonly used and most effective method, and it is also the only method currently recognized as a possible cure for renal cancer, but most patients have lost the best opportunity for surgery when they are diagnosed; Drug properties make renal cancer insensitive to radiotherapy, chemotherapy and hormone therapy; α-interferon (INF-α) and interleukin 2 (IL-2) are biological immunotherapeutic preparations that have been studied more at present. Chemotherapy has a certain curative effect, but only some patients have achieved good curative effect, and the curative effect is not long-lasting, and the treatment has brought many adverse reactions, such as nausea, vomiting, bone marrow suppression, etc., which have brought difficulties to long-term treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1 Preparation of capsules

[0020] Preparation of astragalus water extract: pulverize astragalus into coarse powder, add 7 times of water to soak for 1 hour, reflux for 2 hours, filter, and use the filtrate for later use. Add the medicine residue to 5 times of water, reflux and extract for 1.5 hours, filter, and combine the two filtrates , Concentrated to one-third of the original volume, add 95% ethanol until the alcohol concentration reaches 70%, stand still, precipitate, filter, dry the resulting precipitate, superfinely pulverize to 300 mesh, to obtain the astragalus water extract .

[0021] Preparation of ethanol extract of Solanum sinensis: pulverize Solanum sinensis into coarse powder, add 8 times the amount of 75% ethanol solution to heat and reflux for extraction, extract for 1.5h, filter, and use the filtrate for later use, add 6 times the amount of 75% of the medicine residue The ethanol solution was heated and refluxed for extraction, extracted for 1 h, ...

Embodiment 2

[0025] Example 2 Efficacy test of Chinese medicine composition in treating renal cell carcinoma

[0026] normal information

[0027] Thirty-eight renal cancer patients receiving chemotherapy were randomly selected, including 26 males and 12 females, aged 41.6-70.3 years old, with an average age of 55.7 years. The 38 patients were randomly divided into two groups, the test group and the control group. There was no statistical difference between the two groups in terms of age, gender, and kidney cancer stage.

[0028] Treatment method: The control group maintains the original chemotherapy administration method, and the test group additionally takes the capsule prepared in Example 1, 3 times a day, 3-5 capsules each time, for 3 months.

[0029] Evaluation method: After taking the medicine for 3 months, the liver and kidney function and hematuria of all patients are routinely checked to evaluate the side effects of the treatment. During the follow-up of the patients, B-ultrasound, CT, ch...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for treating kidney cancer, and belongs to the field of a traditional Chinese medicine. The traditional Chinese medicine composition is made from radix astragali, solanum nigrum and an alcohol extract / aqueous extract of salvia chinensis. The effective component content of the composition is increased, thereby increasing the medicine efficacy. During treatment of kidney cancer through combined chemotherapy, recurrence and metastasis of kidney cancer can be effectively prevented, an effect of toxicity reduction and effect increase is achieved, the adverse reaction occurring when a patient who suffers from kidney cancer uses chemotherapic agents for a long time is prevented, and the life quality of the patient is improved.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine composition for treating kidney cancer and belongs to the field of traditional Chinese medicine. Background technique [0002] Renal cancer is also known as renal cell carcinoma. This disease originates from renal tubular epithelial cells and can occur in any part of the kidney parenchyma, but it is more common at the upper and lower levels. In my country, renal cancer accounts for about 3% of all adult malignant tumors. It is the urinary system. One of the most common malignant tumors, its incidence is second only to bladder cancer, and the older the age, the higher the incidence. The etiology of kidney cancer is not yet clear. On the one hand, it is related to lifestyle factors such as smoking, drinking, food, obesity, and drugs; on the other hand, it is related to environmental factors, such as occupational exposure to chemicals, radiation, kidney dialysis, etc., and also related to family History, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/81A61P35/00
CPCA61K36/481A61K36/53A61K36/81A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2300/00
Inventor 邸彦橙王书惠解颖田河白吉祥
Owner MUDANJIANG MEDICAL UNIV