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Probiotic fermentation calcium supplement and preparation method thereof

A technology of probiotics and preparations, which is applied in the field of probiotic fermented calcium supplement preparations and its preparation, can solve the problems of side effects, potential safety hazards, and limited efficacy value of calcium products, and achieve the effects of easy absorption by the human body, long shelf life, and stable state

Inactive Publication Date: 2016-12-07
SANZHU FUER PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] In order to solve the disadvantages of existing calcium products such as side effects, potential safety hazards, and limited efficacy and value, the present invention provides a calcium supplementation preparation fermented by probiotics. A large amount of water, after high-pressure extraction, enzymatic treatment, adding glucose, peptone, calcium carbonate, after sterilization, fermented by multiple strains of probiotics, centrifuged to get the centrifugate, added sweeteners, prebiotics, and sterilized to obtain probiotic fermentation Calcium Supplement

Method used

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  • Probiotic fermentation calcium supplement and preparation method thereof
  • Probiotic fermentation calcium supplement and preparation method thereof
  • Probiotic fermentation calcium supplement and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Example 1: Preparation of probiotic fermented calcium supplement preparation A

[0036] The specific preparation method is as follows:

[0037] (1) Extraction: Select 2kg of dry soybeans, sprout them, add 100L water to the bean sprouts, grind them with a colloid mill, and extract under high pressure at 115°C for 60 minutes;

[0038] (2) Enzymatic hydrolysis: when the temperature drops to 45±2°C, maintain a constant temperature, adjust the pH to 8.0 with sodium hydroxide, add 20 g of trypsin, when the pH drops to 7.5, add 2 g of neutral protease, and when the pH drops to At 7.0, end the enzymatic hydrolysis, add glucose 10% (weight g / volume ml), peptone 0.2% (weight g / volume ml), calcium carbonate 2% (weight g / volume ml), autoclave at 115°C for 60 minutes, Obtain sterile enzymatic hydrolyzate;

[0039] (3) Inoculation and fermentation: When the temperature of the sterile enzymatic hydrolyzate drops to 39±2°C, inoculate pre-cultured Bifidobacterium breve (AS 1.2213) bac...

Embodiment 2

[0041] Example 2: Preparation of probiotic fermented calcium supplement preparation B

[0042] The specific preparation method is as follows:

[0043] (1) Extraction: Select 4kg of dry soybeans, sprout them, add 100L water to the bean sprouts, grind them through a colloid mill, and extract under high pressure at 115°C for 60 minutes;

[0044] (2) Enzymatic hydrolysis: when the temperature drops to 45±2°C, maintain a constant temperature, adjust the pH to 8.0 with sodium hydroxide, add 40 g of trypsin, when the pH drops to 7.5, add 4 g of neutral protease, and when the pH drops to At 7.0, end the enzymatic hydrolysis, add glucose 8% (weight g / volume ml), peptone 0.4% (weight g / volume ml), calcium carbonate 3% (weight g / volume ml), autoclave at 115°C for 60 minutes, Obtain sterile enzymatic hydrolyzate;

[0045] (3) Inoculation and fermentation: When the temperature of the sterile enzymatic hydrolyzate drops to 39±2°C, inoculate under aseptic conditions pre-cultured Bifidobact...

Embodiment 3

[0047] Example 3: Preparation of probiotic fermented calcium supplement preparation C

[0048] The specific preparation method is as follows:

[0049] (1) Extraction: Select 6kg of dry soybeans, sprout them, add 100L water to the bean sprouts, grind them through a colloid mill, and extract under high pressure at 115°C for 60 minutes;

[0050] (2) Enzymatic hydrolysis: when the temperature drops to 45±2°C, maintain a constant temperature, adjust the pH to 8.0 with sodium hydroxide, add 60 g of trypsin, when the pH drops to 7.5, add 6 g of neutral protease, and when the pH drops to At 7.0, end the enzymatic hydrolysis, add glucose 6% (weight g / volume ml), peptone 0.5% (weight g / volume ml), calcium carbonate 4% (weight g / volume ml), autoclave at 115°C for 60 minutes, Obtain sterile enzymatic hydrolyzate;

[0051] (3) Inoculation and fermentation: When the temperature of the sterile enzymatic hydrolyzate drops to 39±2°C, inoculate pre-cultured Bifidobacterium breve (AS 1.2213) b...

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Abstract

The invention discloses a probiotic fermentation calcium supplement. The probiotic fermentation calcium supplement is obtained by selecting soybeans, germinating, grinding with a colloid mill, adding a certain amount of water, carrying out high pressure extraction and enzymolysis treatment, adding glucose, peptone and calcium, sterilizing, then fermenting by virtue of multiple probiotics, centrifuging and taking centrifugal liquid, adding a sweetening agent and prebiotics and sterilizing. The probiotic fermentation calcium supplement has the advantages that the probiotics are utilized for carrying out in vitro metabolism, secondary metabolites enter intestinal tracts to be directly absorbed by human body to take effect, negative effects brought about as thalli can not be colonized are avoided, and lactobacilli in the probiotics are utilized for natural metabolism on inorganic calcium to produce organic calcium lactate, so that calcium can be absorbed by the human body more easily, and the probiotic fermentation calcium supplement is a safe, green, environment-friendly, organic and healthy calcium supplement.

Description

technical field [0001] The invention relates to a probiotic fermented calcium supplement preparation capable of effectively promoting calcium absorption and a preparation method thereof, belonging to the technical field of functional foods. Background technique [0002] Calcium is the most abundant and indispensable inorganic element in the human body. 99% of the calcium in the human body is deposited in the bones and teeth to promote their growth and maintain their shape and hardness. l% exists in blood and soft tissue cells, such as calcium ions have an important effect on blood coagulation, blood coagulation disorder occurs when calcium is deficient, and various bleeding symptoms will appear in the human body; calcium ions have an important effect on nerve and muscle excitement and nerve impulse conduction Important role, when calcium is deficient, the human body will appear symptoms such as nerve conduction block and muscle tension abnormality; calcium ions play an impo...

Claims

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Application Information

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IPC IPC(8): A23L11/20A23L33/00A23L11/50A23L11/70
CPCA23V2002/00A23V2200/30
Inventor 吴炳新陆继臣孙筱林褚新红甄宗武
Owner SANZHU FUER PHARMA
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