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Externally-used drug for treating senile vaginitis and preparation method thereof

A vaginitis and senile technology, applied in the field of pharmaceutical preparations, can solve the problems of destroying the pH value of the vagina and normal flora, curing the symptoms but not the root cause, and dysbacteriosis, and achieves simple preparation process and use method, excellent curative effect, and reduced The effect of pH

Inactive Publication Date: 2017-06-13
健务(上海)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, the above methods usually treat the symptoms but not the root cause, and are easy to repeat, and even directly destroy the pH value and normal flora in the vagina, leading to flora imbalance, which can lead to other vaginal diseases

Method used

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  • Externally-used drug for treating senile vaginitis and preparation method thereof
  • Externally-used drug for treating senile vaginitis and preparation method thereof
  • Externally-used drug for treating senile vaginitis and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0034] The external medicament for the treatment of senile vaginitis of the present embodiment is prepared according to the following steps:

[0035] 1. Preparation of traditional Chinese medicine medium: Weigh the traditional Chinese medicine, carbon source and water respectively according to the mass ratio, heat to 100°C after mixing, keep for 5 minutes, cool to 15°C, filter and remove the medicinal residues to prepare the traditional Chinese medicine medium;

[0036] Two, inoculation: the Chinese medicine culture medium that step 1 makes is transferred in the culture container, and bacterial classification is inoculated in the Chinese medicine culture medium of culture container;

[0037] 3. Fermentation: Seal the culture container with sterilized gauze, the thickness of the sealed gauze is 5 layers, then ferment for 30 days, the fermentation temperature is 15°C, and the external medicament for treating senile vaginitis of the present embodiment is obtained; See Table 1 for...

Embodiment 2

[0039] The external medicament for the treatment of senile vaginitis of the present embodiment is prepared according to the following steps:

[0040] 1. Preparation of traditional Chinese medicine medium: Weigh the traditional Chinese medicine, carbon source and water respectively according to the mass ratio, heat to 100°C after mixing, keep for 30 minutes, cool to 20°C, filter and remove the medicinal residues to prepare the traditional Chinese medicine medium;

[0041] Two, inoculation: the Chinese medicine culture medium that step 1 makes is transferred in the culture container, and bacterial classification is inoculated in the Chinese medicine culture medium of culture container;

[0042] 3. Fermentation: the culture container is sealed with a sterilized towel, the thickness of the sealed towel is 2 to 3 layers, and then fermented for 15 days at a fermentation temperature of 20°C to obtain the external use of the present embodiment for the treatment of senile vaginitis Med...

Embodiment 3

[0044] The external medicament for the treatment of senile vaginitis of the present embodiment is prepared according to the following steps:

[0045] 1. Preparation of traditional Chinese medicine medium: Weigh the traditional Chinese medicine, carbon source and water respectively according to the mass ratio, heat to 100°C after mixing, keep for 20min, cool to 1°C, filter and remove the medicinal residue to prepare the traditional Chinese medicine medium;

[0046] Two, inoculation: the Chinese medicine culture medium that step 1 makes is transferred in the culture container, and bacterial classification is inoculated in the Chinese medicine culture medium of culture container;

[0047] 3. Fermentation: Seal the culture container with sterilized gauze, the thickness of the sealed gauze is 8 layers, then ferment for 60 days, the fermentation temperature is 10°C, and the external medicament for treating senile vaginitis of the present embodiment is obtained; See Table 1 for the s...

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Abstract

The invention discloses an externally-used drug for treating senile vaginitis and a preparation method thereof, relates to a drug preparation prepared from an uncertain structure of the traditional herb through thallus fermentation and especially relates to the externally-used drug for senile vaginitis. The invention aims to provide the externally-used drug for treating senile vaginitis and the preparation method thereof. The drug can be directly externally used; the amount of the harmful bacteria can be reduced in the manner of adjusting the pH value in vagina, increasing the amount of effective microbial community and utilizing the antagonism effect of the acidic environment and beneficial bacteria to the harmful bacteria; and the inherent (special) properties of the Chinese herbal medicine and the secondary metabolite generated by the microbial fermented traditional Chinese medicine are utilized to reinforce the antibacterial function and repair the damaged vaginal wall, so that the effect of treating the senile vaginitis is obvious. The preparation method for the drug provided by the invention comprises the steps: preparing a culture medium, inoculating and fermenting. The invention belongs to the field of medicines.

Description

technical field [0001] The invention relates to a pharmaceutical preparation prepared by fermenting the undetermined structure of traditional herbal medicines, in particular to an external medicament for senile vaginitis. Background technique [0002] Senile vaginitis is common in postmenopausal elderly women. Due to ovarian function decline, estrogen level decreases, vaginal wall atrophy, mucous membrane becomes thinner, glycogen content in epithelial cells decreases, vaginal pH increases and becomes alkaline, local resistance At the same time, due to the atrophy of the vaginal mucosa, thin epithelium, and insufficient blood supply, the resistance of the vagina is reduced, which is convenient for the inflammatory lesions caused by bacterial invasion and reproduction. The main symptoms are increased vaginal discharge and genital itching and burning sensation. Examination showed that the vagina showed senile changes, epithelial atrophy, folds disappeared, and the epithelium ...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P15/02A61K35/747A61K35/744A61K35/741
CPCA61K36/489A61K9/0034A61K35/741A61K35/744A61K35/747A61K36/064A61K36/234A61K36/756A61K2236/19A61K2300/00
Inventor 刘金良
Owner 健务(上海)生物科技有限公司
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