Amino acid peritoneal dialysis solution for dogs and cats and preparation method thereof

A peritoneal dialysate and amino acid technology, applied in the field of animal husbandry and veterinary aquaculture, can solve problems such as increasing the economic burden and emotional distress of dog owners, affecting the quality of life of pet dogs, peritoneal fibrosis, etc. Immunity, reduce irritation effect

Active Publication Date: 2017-07-14
永春县产品质量检验所福建省香产品质量检验中心国家燃香类产品质量监督检验中心福建
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the peritoneal dialysis solution of dogs and cats generally uses the dialysis solution used by humans with glucose as the main osmotic agent. Because of its high sugar, hypertonicity, low pH value and the production of glucose degradation products, it will cause changes in the structure and function of the peritoneum, and eventually

Method used

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  • Amino acid peritoneal dialysis solution for dogs and cats and preparation method thereof
  • Amino acid peritoneal dialysis solution for dogs and cats and preparation method thereof
  • Amino acid peritoneal dialysis solution for dogs and cats and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] An amino acid peritoneal dialysis solution for dogs and cats, every 1000 mL of the dialysis solution consists of the following components by weight: L-arginine 1.0 g, L-histidine 1.0 g, L-isoleucine 0.6 g, L- -Leucine 1.3 g, L-lysine 0.8 g, L-methionine 0.4 g, L-phenylalanine 0.7 g, L-threonine 0.4 g, L-tryptophan 0.2 g, L-valine Acid 0.8 g, taurine 0.1 g, vitamin B 6 0.2 g, astragalus polysaccharide 0.1 g and calcium chloride 0.1 g, and the balance is water for injection.

[0033] The specific steps for preparing each 1000 mL of dialysate are as follows:

[0034] (1) Use a graduated cylinder to measure an appropriate amount of water for injection, and add it to a 1000mL beaker;

[0035] (2) Weigh L-arginine, L-histidine, L-isoleucine, L-leucine, L-lysine, L-methionine, L-phenylalanine respectively according to the above weight Acid, L-threonine, L-tryptophan, L-valine, and taurine were added to the beaker, placed on a magnetic stirrer, and stirred to dissolve;

[...

Embodiment 2

[0040] An amino acid peritoneal dialysis solution for dogs and cats, every 1000 mL of the dialysis solution consists of the following components by weight: L-arginine 1.32 g, L-histidine 1.22 g, L-isoleucine 0.63 g, L- -Leucine 1.40 g, L-lysine 0.90 g, L-methionine 0.45 g, L-phenylalanine 0.72 g, L-threonine 0.58 g, L-tryptophan 0.20 g, L-valine Acid 0.80 g, taurine 0.20 g, vitamin B 6 0.20 g, astragalus polysaccharide 0.25 g and calcium chloride 0.15 g, and the balance is water for injection.

[0041] All the other are with embodiment 1.

Embodiment 3

[0043] An amino acid peritoneal dialysis solution for dogs and cats, every 1000 mL of the dialysis solution consists of the following components by weight: L-arginine 1.44 g, L-histidine 1.12 g, L-isoleucine 0.62 g, L- -Leucine 1.35 g, L-lysine 0.95 g, L-methionine 0.48 g, L-phenylalanine 0.70 g, L-threonine 0.48 g, L-tryptophan 0.25 g, L-valine Acid 0.88g, Taurine 0.25g, Vitamin B 6 0.25 g, astragalus polysaccharide 0.30 g and calcium chloride 0.20 g, and the balance is water for injection.

[0044] All the other are with embodiment 1.

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Abstract

The invention discloses an amino acid peritoneal dialysis solution for dogs and cats and a preparation method thereof, and belongs to the fields of animal husbandry, veterinarian and breeding industry. The peritoneal dialysis solution is composed of the following components by weight (for each 1000 mL): 1.0 to 2.0 grams of L-arginine, 1.0 to 1.6 grams of L-histidine, 0.6 to 0.9 gram of L-isoleucine, 1.3 to 1.5 grams of L-leucine, 0.8 to 1.0 gram of L-lysine, 0.4 to 0.6 gram of L-methionine, 0.7 to 0.8 gram of L-phenylalanine, 0.4 to 0.6 gram of L-threonine, 0.2 to 0.4 gram of L-tryptophan, 0.8 to 1.2 grams of L-valine, 0.1 to 0.3 gram of taurine, 0.2 to 0.3 gram of vitamin B6, 0.1 to 0.3 gram of astragalus polysaccharide, 0.1 to 0.3 gram of calcium chloride, and the balance being water for injection. The provided amino acid peritoneal dialysis solution can well relieve symptoms caused by kidney failure such as hyperitremia, hyperphosphatemia, hypoproteinemia, and the like, and can improve the ultrafiltration function of peritoneum and substance clearance rate.

Description

technical field [0001] The invention belongs to the field of animal husbandry and veterinary breeding, and particularly relates to an amino acid peritoneal dialysis solution for treating renal failure in dogs and cats. Background technique [0002] Renal failure is based on the occurrence of various kidney diseases. Due to the gradual damage of nephrons, the slow development of renal function decline leads to irreversible renal failure. The disease mainly manifests as decreased renal function, stagnation of metabolic waste (especially nitrogen-containing metabolites after protein decomposition), water, electrolyte and acid-base balance disorders, and various endocrine dysfunctions related to the kidneys, so that it cannot maintain A clinical syndrome caused by the stability of the internal environment of the body. In recent years, the problem of renal failure in dogs and cats has attracted more and more attention, and it is imperative to study new methods for effective trea...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61P13/12A61P7/08A61K31/4172A61K31/198A61K31/405A61K31/185A61K31/4415A61K31/715
CPCA61K31/185A61K31/198A61K31/405A61K31/4172A61K31/4415A61K31/715A61K33/14A61K2300/00
Inventor 陆江朱道仙卢炜刘静卢劲晔魏宁周红蕾颜卫李玲
Owner 永春县产品质量检验所福建省香产品质量检验中心国家燃香类产品质量监督检验中心福建
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