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A kind of liquid dressing prepared with pure natural plant extract and preparation method thereof

A technology of liquid dressings and natural plants, applied in medical preparations containing active ingredients, pharmaceutical formulas, medical science, etc., can solve problems such as allergies, unsafe for children, irritating, etc., and achieve the effect of rich sources

Active Publication Date: 2020-12-01
北京紫藤医创医药信息技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The functions of the existing functional dressings and liquid dressings are relatively single or limited, and there are many shortcomings as follows:
It has certain side effects and irritation; when used on a large area or frequently used, these ingredients will be absorbed by the body, resulting in toxic and side effects, especially unsafe for children
Some functional dressings that use silver or other heavy metals as bactericides can also cause heavy metal residues, and even cause chronic poisoning (for example, the Chinese invention patent application with application number 200610083191.8)
[0006] 2. Most of the existing liquid dressings use organic solvents as solvents, which are irritating, can cause allergies, or cause patients to feel pain
[0007] 3. The functions of existing liquid dressings are limited to sterilization and antibacterial effects, but lack the effects of hemostasis and wound healing, so they are actually general disinfectants
[0008] 4. Although the existing liquid dressings are added with chitosan or honeysuckle and other traditional Chinese medicine extracts to produce bactericidal or antibacterial functions, chemical compounds or chemical agents (such as polyvinyl alcohol or polyvinyl butyral) are often added. , polyethylene glycol, etc.) as a film-forming material, the hemostatic effect is poor
[0009] 5. Some existing imported liquid dressings (such as 3M Cavilon or 3M painless protective film spray, liquid dressing Saifurun), although they can form a lipid protective film on the skin surface, they can play the role of covering, isolating and protecting the skin , can promote the repair of injured skin or skin in risky areas, but its function is limited to skin protection, low antibacterial function, no bactericidal, antibacterial effect, and no hemostatic and wound healing effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] (1) Grind the dried bletilla striata pieces, pass through a 10-20 mesh sieve, dry in an oven at 50°C for 1 hour, weigh 200g, add 10 times the amount, namely 2.0L of distilled water, stir evenly, and place overnight. Continue to add water the next day, the ratio of solid to liquid is 1:20, stir and extract in a water bath at 60°C for 1 hour, filter and separate the filter residue, and extract the residue twice. The second water addition is 10 times, the extraction temperature is 60°C and 1 h, and filtered; the third water addition is 5 times, the extraction temperature is 90°C, 0.5 h, cooled to a temperature of 45-50°C, and adjusted When the pH is 5.0, add 250 U / mg cellulase solution, incubate and shake at 45 °C for 5 h, and boil for 5 min to inactivate the enzyme. Combine the filtrates for 3 times, concentrate until viscous, cool to room temperature, add 3 times the volume of ethanol and stir evenly while stirring, so that the alcohol content reaches 70%, let it stand o...

Embodiment 2

[0046] (1) Crush the dried bletilla striata pieces, pass through a 10-20 mesh sieve, dry in an oven at 50°C for 1 hour, weigh 200g, add 10 times the amount (2.0L) of distilled water, stir evenly, and place overnight. Continue to add water the next day, the ratio of solid to liquid is 1:20, stir and extract in a water bath at 60°C for 1 hour, filter and separate the filter residue, and extract the residue twice. The second water addition is 10 times, the extraction temperature is 60°C and 1 h, and filtered; the third water addition is 5 times, the extraction temperature is 90°C, 0.5 h, cooled to a temperature of 45-50°C, and adjusted When the pH is 5.0, add 250 U / mg cellulase solution, incubate and shake at 45 °C for 5 h, and boil for 5 min to inactivate the enzyme. Combine the filtrates for 3 times, concentrate until viscous, then use papain 8-10mg / g at a temperature of 45-50°C and a pH value of 7.0-7.5, refine the treatment for 120-150min, inactivate the enzyme, cool to room ...

Embodiment 3

[0051] (1) Crush the dried bletilla striata pieces, pass through a 10-20 mesh sieve, dry in an oven at 50°C for 1 hour, weigh 200g, add 10 times the amount (2.0L) of distilled water, stir evenly, and place overnight. Continue to add water the next day, the ratio of solid to liquid is 1:20, stir and extract in a water bath at 60°C for 1 hour, filter and separate the filter residue, and extract the residue twice. The second water addition is 10 times, the extraction temperature is 60°C and 1 h, and filtered; the third water addition is 5 times, the extraction temperature is 90°C, 0.5 h, cooled to a temperature of 45-50°C, and adjusted When the pH is 5.0, add 250 U / mg cellulase solution, incubate and shake at 45°C for 5 h, and boil for 5 min to inactivate the enzyme. Combine the filtrates for 3 times, concentrate until viscous, cool to room temperature, add 3 times the volume of ethanol and stir evenly while stirring, so that the alcohol content reaches 75%, let stand overnight, ...

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PUM

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Abstract

The invention discloses a liquid dressing for preparing a pure natural plant extract. The liquid dressing is prepared from aliphatic ester, linoleic acid, bletilla hydroalcoholic extract, melaleuca oil and plant alpha-vitamin E. The liquid dressing comprises the following components in parts by weight: 800-860 parts of aliphatic ester, 80-90 parts of linoleic acid, 20-50 parts of bletilla hydroalcoholic extract, 20-50 parts of melaleuca oil, 0.1-0.3 part of plant alpha-vitamin E and 20-50 parts of purified water. Various raw materials of the product disclosed by the invention are selected from natural plants, the source is abundant and the extraction and refining processes are safe and nontoxic; the components are simple; the liquid dressing is fine and smooth; the time for forming film is short; the antibacterial effect is excellent; the liquid dressing is free from drug resistance; the common curative effects of antibiosis, wound protection, healing promotion, and the like, of the dressing are kept, and meanwhile, the hemostatic performance of the dressing is promoted; and the five effects of wound protection, bacteriostat, hemostasis, tissue regeneration promotion, anticorrosion and wound regeneration and healing promotion are achieved.

Description

technical field [0001] The invention relates to the field of medical dressings, in particular to a liquid dressing prepared from pure natural plant extracts. Background technique [0002] Human skin is an important organ that is most vulnerable to trauma caused by various external factors (such as burns, bumps, solar dermatitis, etc.), and is often damaged by various dipping or friction, such as bedsores, pressure sores, sunburn, infants, etc. Diaper dermatitis (red buttocks and diaper rash) leads to microbial growth, bacterial infection, various complications, increased medical costs and psychological burden on patients, and even life-threatening in severe cases. Therefore, the effective care of skin wounds is an important content of research in the field of medicine, and it is also an important measure for daily personal skin care at home. [0003] The traditional treatment and care methods for skin wounds are to cover them with powdered drugs, or make them into band-aids...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61L26/00
CPCA61L26/0057A61L26/0066A61L2300/30A61L2300/404A61L2300/412
Inventor 张国成胡志林钟迪钟建平
Owner 北京紫藤医创医药信息技术有限公司
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