Oral ulcer film and method for preparing same

Abstract

The invention provides an oral ulcer film. 1000-1500 parts of oral ulcer film comprise, by weight, 3-10 parts of hexadecylpyridinium chloride, 3-10 parts of clotrimazole, 3-10 parts of dyclonine hydrochloride, 3-10 parts of lidocaine, 3-15 parts of chitosan, 0.005-0.015 part of betamethasone sodium phosphate, 15-25 parts of polyvinyl alcohol, 25-50 parts of sodium alginate, 100-150 parts of ethyl alcohol and the balance distilled water. The invention further provides a method for preparing the oral ulcer film. The oral ulcer film and the method have the advantages that the oral ulcer film is high in adhesive ability, medicines can be directly applied to ulcer positions, can directly reach focuses and can quickly act, direct effects can be realized, inflammation can be quickly diminished, pain can be quickly relieved, and the ulcer positions can be quickly healed; the oral ulcer film cannot be easily washed away by saliva and can resist elimination effects of the saliva and swallowing to a certain extent, and accordingly the action time of the medicines in lesion regions can be prolonged; the medicines cannot easily reach positions except for the focuses, and accordingly negative influence on internal environments of oral cavities can be prevented; the oral ulcer film is stable in efficacy and convenient to carry and has unique treatment merits.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an oral ulcer film and a preparation method thereof, which are used for treating oral ulcer. Background technique [0002] Oral ulcers, commonly known as "oral ulcers", are the most common oral mucosal diseases. They can occur in men, women, and children all year round. There are various types, including recurrent oral ulcers, traumatic oral ulcers, Behçet's disease, and chemoradiotherapy-induced oral ulcers. , can occur in any part of the oral mucosa, and is more common in areas with poor oral mucosal keratosis, such as lips, cheeks, tongue, soft palate, vestibular groove, etc. In severe cases, it can also affect the pharyngeal mucosa. The clinical manifestations of oral ulcers are isolated round or oval ulcers, single or multiple, with a central depression of the ulcer, covered with a yellow pseudomembrane, surrounded by a congested red halo zone, with clear border...

AI Technical Summary

Problems solved by technology

Due to the particularity of the oral environment, there is saliva in the oral cavity, as well as the activities of the tongue and the swallowing activities of the patient. After the traditional drug dosage forms for the treatment of oral ulcers, such as powders and sprays, are used on the ulcers in the oral cavity, they are easily absorbed by saliva. Dilutes and washes down, so works for less time and is less effective

And some buccal tablets, antibacterial mouthwash, etc. not only make the ulcer absorb the medicine, but also make the whole oral mucosa absorb the medicine, which is easy to cause the imbalance of oral flora.

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